Results 41 to 50 of about 27,038 (208)

Generalized FitzHugh-Nagumo equations with Caputo gH-differentiability: A novel fuzzy fractional approach to digital memristor networks.

PLoS ONE
The fuzzy fractional generalized FitzHugh-Nagumo differential equations (FFGFH-NDEs) is a well-known and generalized model that plays a significant role in biological systems, including complex synchronization in brain networks, cardiac dynamics ...
Muhammad Yousuf, Uzma Ahmad, Ghulam Muhammad, Hamed Alsulami   +3 more
doaj   +1 more source

Egg production evaluation of laying hens by multivariate analysis

Arquivo Brasileiro de Medicina Veterinária e Zootecnia
This study aimed to verify the existence of differences between hens from the Barred Plymouth Rock (PRB) breed and White Plymouth Rock (PRW) breed by multivariate analysis of weekly egg production and cumulative during the years of 1998 and 2010, from ...
P.B. Ferreira, P.R.N. Rorato, F.C.B. Mello, B. Bevilaqua, A. Macedo, L.B.P. Brittes   +5 more
doaj   +1 more source

Cell Cycle Control of Nuclear Metabolism Couples Phosphatidylinositol Signaling to Histone Methylation

Advanced Science, EarlyView.
Nuclear metabolism oscillates during cell cycle progression. Quantitative chromatome proteomics and imaging reveal phase‐specific dynamics of PIP5K1A and nuclear PIP2, linking phosphatidylinositol metabolism to histone methylation. This work identifies nuclear lipid metabolism as a previously unrecognized regulatory axis coordinating chromatin ...
Antoni Gañez‐Zapater, Savvas Kourtis, Camilla Reiter Elbæk, Lorena Espinar, Carolina Toro‐Márquez, Albert Coll‐Manzano, Alfredo Smiriglia, Laura García‐López, Laura Wiegand, Maria Guirola, Frédéric Fontaine, Andrea Morandi, André C. Müller, Sara Sdelci   +13 more
wiley   +1 more source

Zinc Exposure Causes Disulfidptosis to Induce Miscarriage by Up‐Regulating GATA1/METTL1/SLC7A11 Axis

Advanced Science, EarlyView.
Zn exposure up‐regulates GATA1, promoting GATA1‐mediated METTL1 and SLC7A11 transcription. It also enhances METTL1‐mediated m7G modification on SLC7A11 mRNA, increasing SLC7A11 mRNA stability. Ultimately, Zn exposure up‐regulates SLC7A11 at both transcriptional and post‐transcriptional levels, causing disulfidptosis. Knockdown of murine Slc7a11, Gata1,
Wenxin Huang, Yi Sun, Yanxin Wang, Haijun Yan, Xiaoping Yue, Weidong Wu, Xueyu Chen, Jinfang Zhang, Yanbing Lin, Qiong Lei, Nan Ji, Shuaishuai Xing, Liqin Zeng, Qingzheng Kang, Depeng Zhao, Geng Guo, Huidong Zhang   +16 more
wiley   +1 more source

A Multidimensional Comparative Analysis of Black Sea Coastal Cities: An Urban Planning Perspective

Land
Coastal cities are complex spatial systems shaped by intertwined economic, environmental, demographic, and governance pressures. This study develops a multidimensional comparative framework to analyze coastal cities in the Black Sea basin across five ...
Merve Sipahi, Serkan Sipahi, Elife Büyüköztürk, Ahmet Emre Dinçer   +3 more
doaj   +1 more source

Essential Factors Determining the Quality of Population Life

Socialiniai Tyrimai, 2018
The purpose of the article is to generalize methods used in the world practice for assessing the quality of life, to identify the main factors of differentiation of the quality of life in the regions of the Republic of Belarus.
Valentina Ivanovna Lialikova, Jelena Nikolajevna Kalinina, Skaidrė Žičkienė   +2 more
doaj   +1 more source

Dissecting the Ecological Structure of Health and Disease in the Global Gut Microbiome

Advanced Science, EarlyView.
We introduce Wiredancer, a framework that identifies three continuous ecological factors of the gut microbiota. These factors exhibit distinct patterns across health and disease, jointly capturing disrupted ecological stability and offering a new perspective for precision diagnostics and therapeutic strategies.
Baoyuan Zhu, Shuhao Chen, Yunheng Diao, Wei Wang, Yuanyuan Huang, Liqin Liang, Xiaodan Lu, Rui Han, Minxin Guo, Zhaobo Li, Shuhong Wang, Hehua Li, Chenyu Liu, Jing Zhou, Dongsheng Xiong, Xiaobo Li, Yuping Ning, Xuetao Shi, Fengchun Wu, Kai Wu   +19 more
wiley   +1 more source

Differences in concentration of neuron-specific enolase (NSE), neutrophil elastase (NE), and calcium-binding protein S100B in viral diseases: a pilot study focused on normoglycemic COVID-19 patients

Frontiers in Molecular Biosciences
SARS-CoV-2 infection is characterized by a wide spectrum of clinical severity. Despite more than 2 years having passed since the end of the COVID-19 pandemic, the virus’s properties continue to form the basis for developing diagnostic and therapeutic ...
Joanna Adamiec-Mroczek, Agnieszka Bronowicka-Szydełko, Łukasz Lewandowski, Beata Nowak, Anna Turno-Kręcicka, Marta Misiuk-Hojło, Marta Stanek, Agnieszka Matera-Witkiewicz, Magdalena Krupińska, Kinga Gostomska-Pampuch, Edwin Kuźnik, Maciej Rabczyński, Małgorzata Matusiewicz, Izabela Berdowska, Martyna Korbecka, Daria Mykhailova, Zuzanna Przystupa, Beata Smyk, Anna Wojakowska, Amedeo Amedei, Małgorzata Trocha, Katarzyna Madziarska   +21 more
doaj   +1 more source

Diversity of Pharmaceuticals Enhances Antibiotic Resistance in the Invertebrate Gut via Biofilm‐Mediated Mechanisms

Advanced Science, EarlyView.
Pharmaceutical diversity acts as an independent driver of antibiotic resistance in soil invertebrates. While bulk soil remains unaffected, the collembolan gut microbiome exhibits significant resistance gene enrichment under complex chemical exposure and diurnal warming.
Yi‐Fei Wang, Ya‐Ning Wang, Da Lin, Jia‐Yang Xu, Feng‐Yuan Qi, Hui‐Ling Cui, Hui‐Jie Lu, Min Qiao, Edward Topp, Dong Zhu, Matthias C. Rillig, Yong‐Guan Zhu   +11 more
wiley   +1 more source

Tetrastigma Hemsleyanum Polysaccharide Suppresses Triple‐Negative Breast Cancer by Disrupting the Hippo‐YAP/TEAD4‐PDIA4 Axis and Endoplasmic Reticulum Stress Adaptation

Advanced Science, EarlyView.
ABSTRACT Triple‐negative breast cancer (TNBC) exhibits addiction to chronic endoplasmic reticulum (ER) stress, which sustains an aggressive metastatic phenotype through activation of the unfolded protein response (UPR). Here, we identify a previously unrecognized “ER‐stress addiction” axis in which the Hippo pathway effector TEAD4 directly ...
Yini Shang, Wentao Si, Youxue Zhang, Jialin Liu, Huaixi Zhang, Yafei Li, Hongmeng Su, Wei Jiang, Zhishan Ding, Lihong Wang   +9 more
wiley   +1 more source