Results 11 to 20 of about 15,681 (187)
Clausius/Cosserat/Maxwell/Weyl Equations: The Virial Theorem Revisited [PDF]
, 2015 In 1870, R. Clausius found the virial theorem which amounts to introduce the trace of the stress tensor when studying the foundations of thermodynamics, as a way to relate the absolute temperature of an ideal gas to the mean kinetic energy of its ...
Pommaret, Jean-François
core +3 more sources
Localisation and colocalisation of KK-theory at sets of primes
, 2010 Given a set of prime numbers S, we localise equivariant bivariant Kasparov theory at S and compare this localisation with Kasparov theory by an exact sequence.
A. Neeman +16 more
core +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
, 2013 Quantum codes with low-weight stabilizers known as LDPC codes have been actively studied recently due to their simple syndrome readout circuits and potential applications in fault-tolerant quantum computing.
Freedman M., Hatcher A., Tillich J.-P.
core +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Forgotten Motives: the Varieties of Scientific Experience
, 2014 Personal recollections about Alexandre Grothendieck and early days of his theory of motivesComment: 10 pages. Small corrections inserted. Published in: "Alexandre Grothendieck: A Mathematical Portrait." Ed.
Manin, Yuri I.
core +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Matrix factorizations via Koszul duality
, 2013 In this paper we prove a version of curved Koszul duality for Z/2Z-graded curved coalgebras and their coBar differential graded algebras. A curved version of the homological perturbation lemma is also obtained as a useful technical tool for studying ...
Bondal +3 more
core +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source