Results 91 to 100 of about 774,237 (309)
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
We introduce the notion of "covering homology" of a commutative ring spectrum with respect to certain families of coverings of topological spaces. The construction of covering homology is extracted from Bokstedt, Hsiang and Madsen's topological cyclic homology.
Brun, Morten +2 more
openaire +3 more sources
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
ObjectiveTo determine the drug sensitivity and molecular typing characteristics of Klebsiella pneumoniae isolated from meat and diarrhea samples in a local area.MethodsSeventy-one strains of K.pneumoniae were isolated from 118 meat food (chicken and pork)
QUE Fengxia +5 more
doaj +1 more source
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Platelet-rich fibrin, the coagulated plasma fraction of blood, is commonly used to support natural healing in clinical applications. The rat calvaria defect is a standardized model to study bone regeneration.
Karol Ali Apaza Alccayhuaman +7 more
doaj +1 more source
The author is concerned with the following question: Does every closed, orientable, irreducible 3-manifold M with \(\pi_ 1(M)\) infinite have a finite sheeted cover \(\tilde M\) with infinite \(H_ 1(\tilde M) ?\) Such an \(\tilde M\) would be a Haken manifold, so the positive answer to this question would imply existence of finite sheeted Haken covers ...
openaire +2 more sources
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Xia Yu,1,* Yingxia He,2,* Yuzhen Gu,1,* Tingting Zhang,1 Fengmin Huo,1 Qian Liang,1 Jing Wu,1 Yan Hu,2 Xuan Wang,2 Wei Tang,2 Hairong Huang,1 Guan Liu2 1National Clinical Laboratory on Tuberculosis, Beijing Key Laboratory on Drug-Resistant ...
Wu J +11 more
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