Results 121 to 130 of about 774,237 (309)

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

open access: yesFEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar   +4 more
wiley   +1 more source

Overexpression of a Ran GTPase homologous gene, FaRan from tall fescue, in transgenic Arabidopsis

open access: yes, 2011
We isolated and characterized a novel Ran GTPase homologous gene, FaRan from tall fescue (Festuca arundinacea Schreb.). Reverse transcriptase polymerase chain reaction (RT-PCR) analysis indicated that FaRan is broadly expressed in old mature leaves ...
Y. L. Fan, S. H. Lü, C. X. Jin
core   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

open access: yesFEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu   +5 more
wiley   +1 more source

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

open access: yesFEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

One parameter Viscosity-Temperature Correlation for Homologous n-Alkanes Series from CH4 to C20H42

open access: yesJournal of Engineering and Sustainable Development, 2012
The main aim of this paper is to establish a correlation for prediction the dynamic viscosity of homologous n-alkanes from CH4 to C20H42 at isobaric condition within a given temperature range.
Harith Hasoon Jasim
doaj  

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

open access: yesFEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson   +2 more
wiley   +1 more source

Glycoprotein B homologous recombination.

open access: yes, 2015
The putative C genogroup shows full identity with either genogroup A or B partial gB nt sequence according to the portion of the hypervariable region considered. This arrangement is consistent with the outcome of homologous recombination. The highlighted
David C. Bloom (75605)   +10 more
core   +1 more source

Heterologous booster vaccination enhances antibody responses to SARS-CoV-2 by improving Tfh function and increasing B-cell clonotype SHM frequency

open access: yesFrontiers in Immunology
Heterologous prime-boost has broken the protective immune response bottleneck of the COVID-19 vaccines. however, the underlying mechanisms have not been fully elucidated.
Yanli Song   +10 more
doaj   +1 more source

Homology and persistent homology

open access: yes, 2020
Treballs Finals de Grau de Matemàtiques, Facultat de Matemàtiques, Universitat de Barcelona, Any: 2020, Director: Francisco Belchí ...
openaire   +1 more source

The homology of a lattice

open access: yesDiscrete Mathematics, 1971
AbstractWith each bounded lattice L is associated a simplicial complex KL. If X is a cross-cut of L, then a simplicial complex KX is defined. It is shown that the geometric realizations of KX and KL are homotopy equivalent.
openaire   +2 more sources

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