Results 161 to 170 of about 581,114 (248)

Sperm‐Derived CircRNA‐1572 Regulates Embryogenesis and Zygotic Genome Activation by Targeting CCNB2 via Bta‐miR‐2478‐L‐2

open access: yesAdvanced Science, EarlyView.
Sperm‐derived circRNA‐1572 competitively binds to bta‐miR‐2478‐L‐2 through a “sponge” mechanism to regulate cyclin B2 (CCNB2) expression, thereby modulating the distribution of fibrous actin (F‐actin) in early pig embryos, ensuring proper chromosome segregation during mitosis, and facilitating normal embryo cleavage and zygotic genome activation.
Yanfang Wu   +10 more
wiley   +1 more source

Frozen Cadaveric Rib Grafts in Primary or Revision Rhinoplasty: A Systematic Review and Meta-analysis. [PDF]

open access: yesPlast Reconstr Surg Glob Open
Mrad MA   +8 more
europepmc   +1 more source

Assessment and Mitigation of CRISPR‐Cas9‐Induced Nontargeted Translocations

open access: yesAdvanced Science, EarlyView.
Various inverted repeat elements are dispersed throughout genomes. This study reveals that these elements can cause significant chromosomal rearrangements when CRISPR editing occurs in their proximity. The risk can be mitigated by incorporating inverted repeat‐homologous segments into the CRISPR system, which represents a promising strategy for ...
Zhiyang Hou   +6 more
wiley   +1 more source

Ultraviolet Irradiation of Human Plasma to Control Homologous Serum Jaundice [PDF]

open access: bronze, 1948
Albert M. Wolf   +4 more
openalex   +1 more source

De Novo Reconstruction of 3D Human Facial Images from DNA Sequence

open access: yesAdvanced Science, EarlyView.
This study introduces Difface, a novel deep‐learning model for reconstructing 3D facial images only from DNA data. By integrating transformer networks, spiral convolutions, and a diffusion model, Difface directly aligns high‐dimensional SNP data with 3D facial structures.
Mingqi Jiao   +11 more
wiley   +1 more source

Application of a replicative targetable vector system for difficult-to-manipulate streptomycetes. [PDF]

open access: yesAppl Microbiol Biotechnol
Gomez-Escribano JP   +6 more
europepmc   +1 more source

BAG2 Inhibits Cervical Cancer Progression by Modulating Type I Interferon Signaling through Stabilizing STING

open access: yesAdvanced Science, EarlyView.
Based on IP‐MS analysis, BAG2 is confirmed to be essential for ubiquitination and protein homeostasis regulation of STING in cervical cancer. BAG2 inhibits the ubiquitination and degradation of STING by forming a complex with STUB1, thereby activating the type I IFN signaling pathway and inhibiting the development of cervical cancer.
Shijie Yao   +6 more
wiley   +1 more source

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