Results 161 to 170 of about 1,318,508 (390)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

One parameter Viscosity-Temperature Correlation for Homologous n-Alkanes Series from CH4 to C20H42

Journal of Engineering and Sustainable Development, 2012
The main aim of this paper is to establish a correlation for prediction the dynamic viscosity of homologous n-alkanes from CH4 to C20H42 at isobaric condition within a given temperature range.
Harith Hasoon Jasim
doaj  

Heterologous booster vaccination enhances antibody responses to SARS-CoV-2 by improving Tfh function and increasing B-cell clonotype SHM frequency

Frontiers in Immunology
Heterologous prime-boost has broken the protective immune response bottleneck of the COVID-19 vaccines. however, the underlying mechanisms have not been fully elucidated.
Yanli Song, Jiaolei Wang, Zhihui Yang, Qian He, Chunting Bao, Ying Xie, Yufang Sun, Shuyan Li, Yaru Quan, Huijie Yang, Changgui Li   +10 more
doaj   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Structural and Thermodynamic Origins of Ligand Specificity in Homologous PDZ Domains from the Tiam-Family of Guanine Exchange Factors [PDF]

, 2011
Ernesto J. Fuentes, Tyson R. Shepherd
openalex   +1 more source

Learning normal asymmetry representations for homologous brain structures [PDF]

, 2023
Duilio Deangeli, Emmanuel Iarussi, Juan Pablo Princich, Mariana Bendersky, Ignacio Larrabide, José Ignacio Orlando   +5 more
openalex   +1 more source

Protein O‐glycosylation in the Bacteroidota phylum

FEBS Open Bio, EarlyView.
Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns, Dennis Svedberg, André Mateus   +2 more
wiley   +1 more source

T and B cell responses in different immunization scenarios for COVID-19: a narrative review

Frontiers in Immunology
Vaccines against COVID-19 have high efficacy and low rates of adverse events. However, none of the available vaccines provide sterilizing immunity, and reinfections remain possible.
Eva Piano Mortari, Francesca Ferrucci, Irini Zografaki, Rita Carsetti, Luciano Pacelli   +4 more
doaj   +1 more source

supplementary data. "Homologous recombination deficiency and Cyclin E1 amplification are correlated with immune cell infiltration and survival in high-grade serous ovarian cancer"

, 2022
Bart A. van Wagensveld
openalex   +2 more sources

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

FEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić, Darija Putar, Lucija Mijanović, Igor Weber   +3 more
wiley   +1 more source