Results 311 to 320 of about 1,084,291 (336)

In Vivo DNA Assembly in <i>Yarrowia lipolytica</i>. [PDF]

ACS Synth Biol
Jiang W, Georgiadis I, Fumagalli T, Wang S, Vasileiou C, Dahlin J, Borodina I.   +6 more
europepmc   +1 more source

Pathogenicity of Mediator Complex Subunit 27 (MED27) in a Neurodevelopmental Disorder with Cerebellar Atrophy

Advanced Science, EarlyView.
MED27 is one of the 26 subunits in the human Mediator complex (MED). Neurodevelopmental disorder‐causing MED27 genetic variants induce instability of MED, leading to disrupted DNA occupancy, altered chromatin interaction, and subsequent transcriptional dysregulation of critical downstream genes, including master regulatory transcription factors ...
Nuermila Yiliyaer, Xiaocheng Li, Tianyu Guo, Haiying Zhou, Lihai Gong, Luowei Yuan, Yang Fu, Yulong Qiao, Ying Lam Lui, Nuo Chen, Pengfei Lin, Hoi Hung Cheung, Ho Ko, Linyan Meng, Xiao Chen, Yong Lei, Kin Ming Kwan, Huating Wang, Shen Gu   +18 more
wiley   +1 more source

A novel ST-GCN model based on homologous microstate for subject-independent seizure prediction. [PDF]

Sci Rep
Shi W, Shi Y, Chen F, Zhang L, Wan J.
europepmc   +1 more source

BLOC1S1 Attenuates B. Melitensis 16M LPS‐Triggered Autophagy by Spatial Confinement of TDP‐43

Advanced Science, EarlyView.
This study explores how B. melitensis 16M LPS and BLOC1S1 regulate autophagy in goat spermatogonial stem cells. The 16M LPS is activating AMPK‐dependent autophagy, increasing LC3B‐II/I ratios and lysosomal genes, while Escherichia coli LPS shows no effect.
Shicheng Wan, Miao Han, Mengfei Zhang, Wenbo Chen, Fangde Xie, Xuan Luo, Wenping Wu, Congliang Wang, Donghui Yang, Bin Han, Haijing Zhu, Haisheng Yu, Na Li, Jinlian Hua   +13 more
wiley   +1 more source

Assembly and comparative analysis of the first complete mitochondrial genome of <i>Citrus medica</i> (Rutaceae). [PDF]

Front Plant Sci
Wu X, Liu H, Liao S, Liu X, Xie T, Zheng L, Hong Y, Chen W, Li T.   +8 more
europepmc   +1 more source

Gene Editing of a Susceptibility LncRNA Enhances Broad‐Spectrum Disease Resistance in Rice without Developmental Trade‐Offs

Advanced Science, EarlyView.
Editing susceptibility lncRNAs offers a strategy to enhance disease resistance without yield loss. RESIS, a domestication‐acquired, pathogen‐induced lncRNA, promotes protein N‐terminal acetylation through its interaction with NatA complex. Knockout of RESIS increases translation and confers broad‐spectrum resistance to both fungal and bacterial ...
Wen‐long Zhao, Ye Cheng, Jia‐hui Huang, Jun‐jie Feng, Hui‐yin Pang, Yi‐chao Qin, Zheng‐tong Chen, Yu Cheng, Jian‐ping Lian, Yan‐fei Zhou, Rui‐rui He, Meng‐qi Lei, Zi‐qin Cao, Lu Yang, Chao Yuan, Jie Jiang, Yue‐qin Chen, Yu‐chan Zhang   +17 more
wiley   +1 more source

Discovery of novel radioligand [¹⁸F]AZD9574 for selective imaging of PARP1 in the CNS. [PDF]

Acta Pharm Sin B
Zhou X, Chen K.
europepmc   +1 more source

Litchi LcAP1-1 and LcAP1-2 Exhibit Different Roles in Flowering Time. [PDF]

Plants (Basel)
Gui Q, Wei J, Wu Z, Mo X, Qing H, Shi Y, Guo H, Sheng J, Ding F, Zhang S.   +9 more
europepmc   +1 more source

Homologous Recombination Proficiency in High-Grade Serous Epithelial Ovarian Cancer Tumors: The Dark Side of the Moon. [PDF]

Curr Issues Mol Biol
Pavanello M, Vieira CM, Arenhardt MP, Nogueira-Rodrigues A.   +3 more
europepmc   +1 more source