Results 61 to 70 of about 1,056,106 (302)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Chemical Compositions, Traditional Applications, and Biological Activities of Gnaphalium affine D. Don: A Comprehensive Review

open access: yesMolecules
Gnaphalium affine D. Don (G. affine), a genus within the genus Gnaphalium of the Asteraceae family, is recognized as a significant medicinal resource. Phytochemical investigations identified various bioactive compounds in G. affine, including flavonoids,
Chen Ding   +4 more
doaj   +1 more source

The onset of homologous chromosome pairing during Drosophila melanogaster embryogenesis. [PDF]

open access: yes, 1993
We have determined the position within the nucleus of homologous sites of the histone gene cluster in Drosophila melanogaster using in situ hybridization and high-resolution, three-dimensional wide field fluorescence microscopy.
Agard, DA   +5 more
core  

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Multi-wavelength fluorescence polarization immunoassays for simultaneous detection of amantadine and ribavirin in chicken and human serum

open access: yesFood and Agricultural Immunology, 2021
In this study, a homologous multi-wavelength fluorescence polarization immunoassays (MWFPIA) for rapid determination of amantadine (AMD) and ribavirin (RVB) simultaneously was established.
Liuchuan Guo   +4 more
doaj   +1 more source

Altering symplectic manifolds by homologous recombination [PDF]

open access: yes, 2010
We use symplectic cohomology to study the non-uniqueness of symplectic structures on the smooth manifolds underlying affine varieties. Starting with a Lefschetz fibration on such a variety and a finite set of primes, the main new tool is a method, which ...
Abouzaid, Mohammed, Seidel, Paul
core  

Homology stratifications and intersection homology [PDF]

open access: yesGeometry & Topology Monographs, 1999
A homology stratification is a filtered space with local homology groups constant on strata. Despite being used by Goresky and MacPherson [Intersection homology theory: II, Inventiones Mathematicae, 71 (1983) 77-129] in their proof of topological invariance of intersection homology, homology stratifications do not appear to have been studied in any ...
Rourke, Colin, Sanderson, Brian
openaire   +2 more sources

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Efficacy of Double versus Single Homologous Intrauterine Insemination in Mild Male Factor Infertility and Pregnancy Outcome: A Randomised Controlled Trial [PDF]

open access: yesJournal of Clinical and Diagnostic Research
Introduction: Intrauterine Insemination (IUI) is a cost-effective, minimally invasive, and widely accepted Assisted Reproductive Technology (ART) procedure used to treat infertility.
M Roopa   +4 more
doaj   +1 more source

Safety and immunogenicity of a third-dose homologous BBIBP-CorV boosting vaccination: interim results from a prospective open-label study

open access: yesEmerging Microbes and Infections, 2022
A COVID-19 booster vaccination is being comprehensively evaluated globally due to the emerging concern of reduced protection rate of previous vaccination and circulating Variants of Concern (VOC).
Jingwen Ai   +13 more
doaj   +1 more source

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