Advanced Science, EarlyView.Marker metabolite‐based multi‐omics (genome, transcriptome, and metabolome) analysis is conducted firstly to unravel the genetic basis of thousand seed weight (TSW) in Brassica napus. The released metabolite‐QTL‐gene network represents a valuable genetic resource, and the newly validated BnaTGA6 is a promising target for the improvement of TSW in ...
Long Li +10 more
wiley +1 more source
Homologous alpha satellite sequences on human acrocentric chromosomes with selectivity for chromosomes 13, 14 and 21: implications for recombination between nonhomologues and Robertsonian translocations [PDF]
, 1988 K. H. Andy Choo +4 more
openalex +1 more source
Ex Vivo Spatiotemporal Characterization of Spermatogenesis in Mouse Testicular Organoids
Advanced Science, EarlyView.To date, in vitro spermatogenesis remains a challenge in reproductive medicine. In this study, Sun et al. developed a promising in vitro strategy to generate testicular organoids that enable germ cells from newborn mice to enter meiosis, complete chromosome recombination and synapsis, and develop into haploid spermatids.
Jiachen Sun +9 more
wiley +1 more source
RNA G‐Quadruplex RIBOTAC‐Mediated Targeted Degradation of lncRNA TERRA
Advanced Science, EarlyView.This study introduces a selective RNA degradation strategy targeting long noncoding RNA (lncRNA) TERRA, upregulated in ALT (alternative lengthening of telomeres) cancer cells. Using ribonuclease‐targeting chimeras (RIBOTACs), RNase L is recruited to catalytically degrade TERRA, uncovering a novel approach to affect a disease associated lncRNA in ALT ...
Elias Khaskia +2 more
wiley +1 more source
Cognate homeo-box loci mapped on homologous human and mouse chromosomes. [PDF]
, 1986 Mark Rabin +3 more
openalex +1 more source
Advanced Science, EarlyView.An electrochemical system is designed to convert CO2 into CO2‐derived electrolytes (CDE), mainly containing acetate and formate. The underlying mechanism of acetate metabolism in Halomonas TD80 is explored via ALE. Engineered TD80 produced high‐yield diversified products from CDE.
Chi Wang +18 more
wiley +1 more source
Reduced chromatin accessibility underlies gene expression differences in homologous chromosome arms of diploid Aegilops tauschii and hexaploid wheat. [PDF]
Gigascience, 2020 Lu FH +5 more
europepmc +1 more source
Random Assortment in Inheritance of Distinguishable Homologous Chromosomes
, 1922 Max Coulter
openalex +2 more sources
Amplified DNA in Y1 mouse adrenal tumor cells: isolation of cDNAs complementary to an amplified c-Ki-rasgene and localization of homologous sequences to mouse chromosome 6 [PDF]
, 1984 Donna L. George +3 more
openalex +1 more source
Advanced Science, EarlyView.Genomic data offer a powerful tool for studying the molecular interactions between parasites and their hosts, but they remain scarce for parasitic monogenean flatworms. This study presents the first high‐quality phased genome assembly for monogeneans (Gyrodactylus kobayashii), and uses it to predict key interacting proteins between monogenean parasite ‐
Dong Zhang +17 more
wiley +1 more source