Results 141 to 150 of about 319,606 (332)

Identification of an obesity quantitative trait locus on mouse chromosome 2 and evidence of linkage to body fat and insulin on the human homologous region 20q. [PDF]

open access: bronze, 1997
A. V. Lembertas   +10 more
openalex   +1 more source

The Evolutionarily Conserved TPM1 Super‐Enhancer Drives Skeletal Muscle Regeneration via Mechanotransduction Signaling

open access: yesAdvanced Science, EarlyView.
By integrating biomechanical and epigenetic cues, the evolutionarily conserved TPM1 super‐enhancer drives myogenesis via TEAD4‐mediated chromatin looping. This mechanism produces species‐specific outputs (linear TPM1 mRNA in mice and CircTPM1 in bovine) that activate PI3K/AKT mechanotransduction and the MYH10/MYL3 axis to execute cytoskeletal ...
Ruimen Zhang   +27 more
wiley   +1 more source

Decay of homologous chromosome pairs and discovery of males in the thelytokous fungus-growing ant Mycocepurus smithii. [PDF]

open access: yesSci Rep, 2022
Barros LAC   +5 more
europepmc   +1 more source

Material‐Induced Nuclear Deformation Controls Chromatin Architecture in Adipose Stem Cells

open access: yesAdvanced Science, EarlyView.
Tuning cell and cytoskeleton mechanics modulated nuclear shape and heterochromatin organization in ASCs. Distinct cytoskeletal architectures induced nuclear morphologies from oblate to prolate ellipsoids. Large elongated cells with a structured actin cap exhibited high nuclear strain, driving nuclear envelope deformation and heterochromatin ...
Carlo F. Natale   +6 more
wiley   +1 more source

The Essential Function of SETDB1 in Homologous Chromosome Pairing and Synapsis during Meiosis. [PDF]

open access: yesCell Rep, 2021
Cheng EC   +7 more
europepmc   +1 more source

Identification of 5P Chromosomes in Wheat-Agropyron cristatum Addition Line and Analysis of Its Effect on Homologous Pairing of Wheat Chromosomes [PDF]

open access: gold, 2022
Cuili Pan   +8 more
openalex   +1 more source

Reference‐Guided Chromosome‐by‐Chromosome de novo Assembly at Scale Using Low‐Coverage High‐Fidelity Long‐Reads with HiFiCCL

open access: yesAdvanced Science, EarlyView.
HiFiCCL, as the first assembly framework specifically designed for low‐coverage high‐fidelity reads, improves the assembly quality of existing assemblers and also enhances downstream applications such as large structural variant (SV) detection (>10 000 bp), synteny analysis, pangenome graph construction, and graph‐based individual‐specific germline SVs
Zhongjun Jiang   +9 more
wiley   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

open access: yesAdvanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong   +5 more
wiley   +1 more source

KARYOLOGY OF KARI SHEEP [PDF]

open access: yesPakistan Veterinary Journal, 2007
Kari sheep is an important genetic resource of Pakistan endemic to Chitral in North Western Frontier Province of Pakistan. The objective of the present study was to establish karyotype of this breed.
S. AHMAD AND M. S. KHAN
doaj  

Biochemical and cytological studies of genetic transfer from the Mv genome of Aegilops ventricosa into hexaploid wheat [PDF]

open access: yes, 1978
A double interspecific oross {Triticum turgidum (AB) var. rubroatrum H-l-1 x Ae. ventvicosa (DM°) AP-l} x T.aestivum (ABD) cv. Almatense H-10-1S was carried out in 1950 by M.
Delibes Castro, Angeles   +2 more
core   +1 more source

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