Results 141 to 150 of about 297,547 (335)
Advanced Science, EarlyView.Targeting eRNAs from TNFα‐associated super‐enhancers with ASOs effectively reduces TNFα expression and inflammatory responses in both mouse models and patient‐derived immune cells. The conserved nature of these regulatory regions between species highlights the potential of eRNA‐targeted approaches as a therapeutic strategy for chronic inflammatory ...
Minjeong Cho +12 more
wiley +1 more source
Packing ellipsoids with overlap
, 2012 The problem of packing ellipsoids of different sizes and shapes into an ellipsoidal container so as to minimize a measure of overlap between ellipsoids is considered. A bilevel optimization formulation is given, together with an algorithm for the general
Uhler, Caroline, Wright, Stephen J.
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The homœologous nature of the non-homologous meiotic pairing in Triticum æstivum deficient for chromosome V (5B) [PDF]
, 1963 Ralph Riley, C. Kempanna
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The Essential Function of SETDB1 in Homologous Chromosome Pairing and Synapsis during Meiosis. [PDF]
Cell Rep, 2021 Cheng EC +7 more
europepmc +1 more source
The behavior of homologous chromosomes during meiosis.
PLANT MORPHOLOGY, 2006 Summary:As the results of the isolation of considerable number of tagged mutants defbctive in meiosis from Arabidopsis and other plants, and the introduction of a variety of techniques to analyze chromosomes and proteins in meiocytes into research of these plants, it has become possible to study meiosis at molecular level in plants.
openaire +2 more sources
Advanced Science, EarlyView.This study investigates subgenome evolution and polyploidy in Cypriniformes fish, revealing complex phylogenetic relationships and genomic dynamics. By applying advanced subgenome partitioning methods, it uncovers novel insights into transposon activity and gene fractionation.
Yunyun Lv +14 more
wiley +1 more source
EGFR: New Insights on Its Activation and Mutation in Tumor and Tumor Immunotherapy
Advanced Science, EarlyView.This review provides new perspectives on EGFR's activation, mutations, and their impact on tumor immunotherapy. It summarizes how EGFR is activated and the current EGFR targeting strategy, evaluates their clinical outcomes in combination with immunotherapy, highlighting differential responses in tumors with EGFR wild‐type and different mutants.
Yuanzhuo Gu +7 more
wiley +1 more source
Discrimination of homologous chromosomes of maize with giemsa staining [PDF]
, 1975 Gy. Hadlaczky, László Kálmán
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Advanced Science, EarlyView.In Arabidopsis, the homeostasis of full‐ and hemi‐methylation is mainly regulated by maintenance methylation. The maintenance methylation at hemi‐methylated dyads is highly efficient but the efficiency differs at euchromatic or heterochromatic regions. Nucleosomes impair the hemi‐ to full‐methylation transition. Lagged methylation maintenance after DNA
Hengye Chen, Chenhuan Xu
wiley +1 more source
Pakistan Veterinary Journal, 2007 Kari sheep is an important genetic resource of Pakistan endemic to Chitral in North Western Frontier Province of Pakistan. The objective of the present study was to establish karyotype of this breed.
S. AHMAD AND M. S. KHAN
doaj