Results 121 to 130 of about 314,723 (346)
Advanced Science, EarlyView.This study reveals the molecular mechanism by which the transcription factor FgSge1 regulates mycotoxin biosynthesis and virulence in Fusarium graminearum. FgSge1 binds to the TAARGTTT cis‐element, enabling self‐activation. It recruits the SAGA complex, promotes histone acetylation, and facilitates jet‐like chromatin remodeling, thereby activating ...
Yueqi Zhang +6 more
wiley +1 more source
PLoS Genetics, 2012 Fragile sites are loci of recurrent chromosome breakage in the genome. They are found in organisms ranging from bacteria to humans and are implicated in genome instability, evolution, and cancer.
Nadia Hashash +2 more
doaj +1 more source
Biochemical and cytological studies of genetic transfer from the Mv genome of Aegilops ventricosa into hexaploid wheat [PDF]
, 1978 A double interspecific oross {Triticum turgidum (AB) var. rubroatrum H-l-1 x Ae. ventvicosa (DM°) AP-l} x T.aestivum (ABD) cv. Almatense H-10-1S was carried out in 1950 by M.
Delibes Castro, Angeles +2 more
core +1 more source
Advanced Science, EarlyView.Fluorescent BODIPY‐conjugated thiosemicarbazone ligands and their Ga(III), In(III), and Fe(III) complexes, inspired by Triapine, are developed as theranostic agents. Multiphoton FLIM and confocal microscopy in cancer cells and zebrafish reveal real‐time uptake, mitochondrial localisation, and whilst spectroscopic assays indicated preserved complex ...
Megan J. Green +15 more
wiley +1 more source
Meiotic chromosome movement: what’s lamin got to do with it?
Nucleus, 2019 Active meiotic chromosome movements are a universally conserved feature. They occur at the early stages of prophase of the first meiotic division and support the chromosome pairing process by (1) efficiently installing the synaptonemal complex between ...
Dimitra Paouneskou, Verena Jantsch
doaj +1 more source
The canonical non-homologous end joining factor XLF promotes chromosomal deletion rearrangements in human cells [PDF]
, 2019 Ragini Bhargava +3 more
openalex +1 more source
Advanced Science, EarlyView.In this study, the orange‐muscle giant abalone (Haliotis gigantea) is used as a model to identify a non‐coding SNP that disrupts the interaction between ITGA8 pre‐mRNA and the splicing factor ILF2, leading to altered ITGA8 splicing. These splicing changes promote carotenoid accumulation in abalone muscle through the regulation of tissue remodeling ...
Xiaohui Wei +17 more
wiley +1 more source
MJL-1 is a nuclear envelope protein required for homologous chromosome pairing and regulation of synapsis during meiosis in C. elegans. [PDF]
Sci Adv, 2023 Kim HJ, Liu C, Zhang L, Dernburg AF.
europepmc +1 more source
Packing ellipsoids with overlap
, 2012 The problem of packing ellipsoids of different sizes and shapes into an ellipsoidal container so as to minimize a measure of overlap between ellipsoids is considered. A bilevel optimization formulation is given, together with an algorithm for the general
Uhler, Caroline, Wright, Stephen J.
core +1 more source
T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities
Advanced Science, EarlyView.T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu +7 more
wiley +1 more source