Results 201 to 210 of about 1,130,741 (368)

Ubiquitination in cancer: mechanisms and therapeutic opportunities

open access: yesCancer Communications, EarlyView.
Abstract Ubiquitination, a key post‐translational modification, plays an essential role in tumor biology by regulating fundamental cellular processes, such as metabolism and cell death. Additionally, it interacts with other post‐translational modifications, which are closely linked to tumorigenesis, tumor progression, the tumor microenvironment, and ...
Susi Zhu   +7 more
wiley   +1 more source

Promising Prodiginins Biological Activities

open access: yesChemistry &Biodiversity, EarlyView.
ABSTRACT Prodiginins are a large family of at least 34 pyrrolic compounds, including the well‐studied red pigment prodigiosin. Prodiginins are produced by several microorganisms displaying broad biological activities, including antimicrobial, antiviral, antiparasitic, antiproliferative, and immunosuppressive activities.
María F. Ladetto   +6 more
wiley   +1 more source

Characterization of Button Loci that Promote Homologous Chromosome Pairing and Cell-Type-Specific Interchromosomal Gene Regulation. [PDF]

open access: yesDev Cell, 2019
Viets K   +13 more
europepmc   +1 more source

Potential Herbicidal and Insecticidal (Beneficial) Properties of Nepalese Lemongrass Essential Oil

open access: yesChemistry &Biodiversity, EarlyView.
ABSTRACT Cymbopogon citratus (DC.) Stapf, commonly known as lemongrass, is a member of the Poaceae family and is native to tropical and subtropical regions, including South Asia. The species is renowned for its diverse applications in culinary arts, perfumery, and traditional medicinal practices.
Beáta Baranová   +13 more
wiley   +1 more source

The Molecular Properties of Honey Bee Acetylcholinesterase Reveal Opportunities to Avoid Off‐Target Effects in Insecticide Discovery

open access: yesChemistry – A European Journal, EarlyView.
The structure, dynamics, and kinetics of the essential enzyme acetylcholinesterase (AChE) of honey bee have been studied and compared to AChEs in mosquitoes and mammalians. Profiling of the active sites with selected substrates and AChE inhibitors revealed dramatic differences between the species.
Cecilia Lindgren   +5 more
wiley   +1 more source

Developmental regulation of SPO13, a gene required for separation of homologous chromosomes at meiosis I.

open access: green, 1987
H T Wang   +4 more
openalex   +1 more source

Disruption of salt bridge interactions in the inter‐domain cleft of the tubulin‐like protein FtsZ of Escherichia coli makes cells sensitive to the cell division inhibitor PC190723

open access: yesCytoskeleton, EarlyView.
Abstract FtsZ forms a ring‐like assembly at the site of division in bacteria. It is the first protein involved in the formation of the divisome complex to split the cell into two halves, indicating its importance in bacterial cell division. FtsZ is an attractive target for developing new anti‐microbial drugs to overcome the challenges of antibiotic ...
Sakshi Mahesh Poddar   +3 more
wiley   +1 more source

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