Reduced chromatin accessibility underlies gene expression differences in homologous chromosome arms of diploid Aegilops tauschii and hexaploid wheat. [PDF]
Gigascience, 2020 Lu FH +5 more
europepmc +1 more source
Random Assortment in Inheritance of Distinguishable Homologous Chromosomes
, 1922 Max Coulter
openalex +2 more sources
Existence of several homologous sequences in the Escherichia coli chromosome to the gene for the major outer membrane lipoprotein [PDF]
, 1982 Yao-Xuan Huang +3 more
openalex +1 more source
Mutation update for the ACTN2 gene
Human Mutation, Volume 43, Issue 12, Page 1745-1756, December 2022., 2022 Abstract ACTN2 encodes alpha‐actinin‐2, a protein expressed in human cardiac and skeletal muscle. The protein, located in the sarcomere Z‐disk, functions as a link between the anti‐parallel actin filaments. This important structural protein also binds N‐terminal titins, and thus contributes to sarcomere stability.
Johanna Ranta‐aho +13 more
wiley +1 more source
Direct Evidence for Homologous Sequences on the Paracentric Regions of Human Chromosome 1 [PDF]
, 1994 Bhushan D. Hardas +3 more
openalex +1 more source
Spider Eye Development Editing and Silk Fiber Engineering Using CRISPR‐Cas
Angewandte Chemie International Edition, Accepted Article.CRISPR‐Cas9 gene editing represents an effective and precise technology to induce mutations in the genome, and it has been applied to a wide range of organisms for diverse purposes. However, CRISPR‐based gene editing in spiders has not been reported to date.
Edgardo Santiago Rivera, Thomas Scheibel
wiley +1 more source
Rare surfactant‐related variants in familial and sporadic pulmonary fibrosis
Human Mutation, Volume 43, Issue 12, Page 2091-2101, December 2022., 2022 Abstract The role of constitutional genetic defects in idiopathic pulmonary fibrosis (IPF) is increasingly appreciated. Monogenic disorders associated with IPF affect two pathways: telomere maintenance, accounting for approximately 10% of all patients with IPF, and surfactant biology, responsible for 1%–3% of cases and often co‐occurring with lung ...
Rachel M. Sutton +10 more
wiley +1 more source
Use of homologous expression-secretion signals and vector-free stable chromosomal integration in engineering of Lactobacillus plantarum for alpha-amylase and levanase expression [PDF]
, 1994 Pascal Hols +4 more
openalex +1 more source
Human Mutation, Volume 43, Issue 12, Page 2205-2221, December 2022., 2022 Mutation frequency heat map of spontaneous PTPN11 variants show spatial clustering in the testis due to germline selection explaining the high birth incidence of Noonan syndrome. Some somatic PTPN11 cancer mutations are similarly clustered in testis. Abstract Some spontaneous germline gain‐of‐function mutations promote spermatogonial stem cell clonal ...
Jordan Eboreime +6 more
wiley +1 more source
Shennong 1 Chicken 40K Liquid Chip: Advancing Genetic Research in Chinese Indigenous Chickens
Animal Research and One Health, EarlyView.Based on comprehensive genomic data of Chinese indigenous chickens, we developed a specialized genotyping array for this population. Comparative analyses with published mainstream arrays and evaluations, including genetic assessment of diverse chicken types and gene mining analyses, demonstrated its superior applicability to Chinese indigenous chickens.
Chaoqun Gao +14 more
wiley +1 more source