A methylated human 9-kb repetitive sequence on acrocentric chromosomes is homologous to a subtelomeric repeat in chimpanzees. [PDF]
Didier Thoraval+10 more
openalex +1 more source
Modeling homologous chromosome recognition via nonspecific interactions. [PDF]
Marshall WF, Fung JC.
europepmc +1 more source
From Genome to Geroscience: How DNA Damage Shapes Systemic Decline
Persistent DNA damage triggers systemic secretory responses including damage‐associated molecular patterns (DAMPs), the senescence‐associated secretory phenotype (SASP), and extracellular vesicles (EVs). This non‐cell‐autonomous signaling disrupts intercellular communication, driving organism‐wide dysfunction and aging, and offering new therapeutic ...
Athanasios Siametis, George A. Garinis
wiley +1 more source
Analysis of homologous chromosome pairing in mouse oocytes using a novel microchromosome [PDF]
C. Tease, Graham Fisher
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E2F1, DIAP1, and the presence of a homologous chromosome promote while JNK inhibits radiation-induced loss of heterozygosity in Drosophila melanogaster. [PDF]
Brown J, Su TT.
europepmc +1 more source
ABSTRACT Cyanobacteria are photoautotrophic microorganisms with significant applications in biotechnology. Although many cyanobacteria, including Picosynechococcus sp. (formerly called Synechococcus sp.) PCC 11901 (Picosynechococcus) and Synechocystis sp.
Cecilia Salvagnini+7 more
wiley +1 more source
Caseinolytic mitochondrial matrix peptidase X is essential for homologous chromosome synapsis and recombination during meiosis of male mouse germ cells. [PDF]
Feng HW, Zhao Y, Gao YL, Liu DT, Huo LJ.
europepmc +1 more source
Meiotic cohesin-based chromosome structure is essential for homologous chromosome pairing in Schizosaccharomyces pombe. [PDF]
Ding DQ+5 more
europepmc +1 more source
This review highlights the complex roles of cellular senescence in cancer progression and suppression, discusses the mechanisms and regulatory pathways involved, and evaluates the efficacy of the “One‐Two punch” sequential treatment approach while addressing emerging challenges in this novel therapeutic strategy.
Qiuming Pan+12 more
wiley +1 more source
Ubiquitination in cancer: mechanisms and therapeutic opportunities
Abstract Ubiquitination, a key post‐translational modification, plays an essential role in tumor biology by regulating fundamental cellular processes, such as metabolism and cell death. Additionally, it interacts with other post‐translational modifications, which are closely linked to tumorigenesis, tumor progression, the tumor microenvironment, and ...
Susi Zhu+7 more
wiley +1 more source