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Gene conversions and their relation to homologous chromosome pairing
Philosophical Transactions of the Royal Society of London. B, Biological Sciences, 1986Abstract Gene conversion is the non-reciprocal transfer of DNA sequences from one gene to a related gene elsewhere in the genome. Molecular evidence for its occurrence in higher eukaryotes was first described by our laboratory in 1980 in the two linked human foetal y-globin genes.
O, Smithies, P A, Powers
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On determining the parental origins of homologous chromosomes
Annals of Human Genetics, 1981SUMMARYGiven sets of measurements on a pair of homologous chromosomes from an individual and both his/her parents, methods for estimating the probability that the individual has inherited any particular two of the four parental homologues are discussed and compared. A new method with several desirable properties is proposed.
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Homologous chromosome recognition via nonspecific interactions
2023Abstract In many organisms, most notably Drosophila , homologous chromosomes in somatic cells associate with each other, a phenomenon known as somatic homolog pairing. Unlike in meiosis, where homology is read out at the level of DNA sequence complementarity, somatic homolog pairing
Wallace F. Marshall, Jennifer C. Fung
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Simulation of chromosomal homology searching in meiotic pairing
Journal of Theoretical Biology, 1995A cellular automaton model has been developed to simulate some aspects of chromosome behaviour during meiotic prophase when homologous chromosomes search for each other so that they can pair. Simulations allow one to compare the relative efficiencies of random searching by chromosome shuffling along the inner nuclear membrane or within the lumen of the
D, Dorninger, G, Karigl, J, Loidl
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Phase separation drives pairing of homologous chromosomes
Current Genetics, 2020Pairing of homologous chromosomes is crucial for ensuring accurate segregation of chromosomes during meiosis. Molecular mechanisms of homologous chromosome pairing in meiosis have been extensively studied in the fission yeast Schizosaccharomyces pombe.
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Homologous Association of Oppositely Imprinted Chromosomal Domains
Science, 1996Human chromosome 15q11-q13 encompasses the Prader-Willi syndrome (PWS) and the Angelman syndrome (AS) loci, which are subject to parental imprinting, a process that marks the parental origin of certain chromosomal subregions. A temporal and spatial association between maternal and paternal chromosomes 15 was observed in human T lymphocytes by three ...
J M, LaSalle, M, Lalande
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Homologous chromosome pairing in Schizosaccharomyces pombe
Yeast, 2006AbstractHomologous chromosome pairing is a central feature of meiosis I, contributing to the correct segregation of chromosomes during meiosis. The fission yeast, Schizosaccharomyces pombe, has been widely used to study meiotic chromosome dynamics, partly because studies in this yeast are simplified due to the lack of post‐pairing synaptic structures ...
Jennifer L, Wells +2 more
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The cytogenetics of homologous chromosome pairing in meiosis in plants
Cytogenetic and Genome Research, 2008Three activities hallmark meiotic cell division: homologous chromosome pairing, synapsis, and recombination. Recombination and synapsis are well-studied but homologous pairing still holds many black boxes. In the past several years, many studies in plants have yielded insights into the mechanisms of chromosome pairing interactions.
C G, Bozza, W P, Pawlowski
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Chromosome banding homologies in Swamp and Murrah buffalo
Journal of Heredity, 1981Silver staining of Swamp buffalo (2n = 48) metaphase chromosomes revealed telomeric nucleolus organizer regions (NOR's) located on five pairs of autosomes identified by R-banding as numbers 4 p (submetacentric), 8, 20, 22, and 23 (acrocentrics); interphase nuclei also showed no more than five nucleoli.
D, Di Berardino, L, Iannuzzi
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A study of homologous chromosomes using a morphometric approach
Genome, 1993A previous study of 100 karyotyped metaphase cells has demonstrated the utility of a graphic arts tool in deriving chromosome measurements for relative length determination. In the present study we utilize this same approach to address the question: "What are the average differences in relative lengths between apparently normal homologous chromosomes?"
H F, Mark +6 more
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