Results 161 to 170 of about 773,827 (377)
Topological requirements for homologous recombination among DNA molecules transfected into mammalian cells. [PDF]
, 1985 C T Wake +2 more
openalex +1 more source
Advanced Science, EarlyView.This study presents telomere‐to‐telomere genome assemblies for two populations of Larimichthys crocea. We identified centromere‐specific tandem repeats invaded by LTR/ERV1 retrotransposons, unique 5S rRNA enrichment patterns, and population‐specific structural variants. Comparative genomic analyses further reveal distinct adaptive mechanisms in the MYD
Yu Cui +9 more
wiley +1 more source
Germ-line transmission of a planned alteration made in a hypoxanthine phosphoribosyltransferase gene by homologous recombination in embryonic stem cells. [PDF]
, 1989 Beverly H. Koller +8 more
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Genomic Insights into the Origin, High Fecundity and Environmental Adaptation of Hu Sheep
Advanced Science, EarlyView.The Hu sheep diverged from the Small‐tailed Han sheep ≈1330 years ago, and subsequently migrated from northern to warm and humid southern regions. The genes BMPR1B, UNC5C, and GRID2 play a synergistic role in the superior reproductive traits of Hu sheep.
Zexuan Liu +12 more
wiley +1 more source
Efficient repair of HO-induced chromosomal breaks in Saccharomyces cerevisiae by recombination between flanking homologous sequences. [PDF]
, 1988 Norah Rudin, James E. Haber
openalex +1 more source
Advanced Science, EarlyView.Understanding the virus‐host arms race has been a fascinating topic in virology; contributing significantly to the development of treatments and control strategies for viral diseases. CHV1 employs a sophisticated counter‐defense mechanism in its fungal host by utilizing a viral silencing suppressor to inhibit fungal FMN reductase; thereby modulating ...
Shiyu Zhai +8 more
wiley +1 more source
Production of chimaeric mice containing embryonic stem (ES) cells carrying a homoeobox Hox 1.1 allele mutated by homologous recombination [PDF]
, 1989 Andreas Zimmer, Peter Gruss
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Advanced Science, EarlyView.As an m6A reader, hnRNPA2B1 predominantly regulates specific transcripts (e.g., Ep400, Rrs1) that are essential for chromosome organization and remodeling in an m6A‐dependent manner. Furthermore, it is demonstrated to interact with factors involved in mRNA processing and translation. This dual functionality is pivotal for ensuring the proper occurrence
Lisha Yin +11 more
wiley +1 more source
ACSS2/AATF Drives Soluble FasL‐Mediated CD8+ T Cell Apoptosis in Pancreatic Neuroendocrine Tumors
Advanced Science, EarlyView.This study unveils that ACSS2‐driven acetate metabolism fuels histone pan‐acetylation in pancreatic neuroendocrine tumors (PNETs), remodeling the epigenetic landscape. The ACSS2/AATF axis transcriptionally activates soluble FasL (sFasL), which engages Fas receptors on infiltrating CD8+ T cells to trigger caspase‐8/3‐mediated apoptosis.
Qin Dang +14 more
wiley +1 more source