Results 181 to 190 of about 341,184 (291)

miR-181d coordinates homologous recombination and anti-tumor immune responses in glioblastoma. [PDF]

iScience
Singh G, Singh S, Mohapatra I, Hou J, Ni A, Barik D, Zheng H, Kim S, Sharma M, Lawler S, Vasudevan S, Kokkoli E, Sarangi S, Elinzano H, Wong ET, Martinez-Moreno M, Gokaslan Z, El-Deiry W, Chen CC.   +18 more
europepmc   +1 more source

Carbon Dots for Cancer Theranostics: Synthesis Strategies, Luminescence Properties, and Advances in Bioimaging‐Guided Diagnosis and Therapy

Chemistry – A European Journal, EarlyView.
Lighting up the path to precision oncology: This review comprehensively summarizes the rational design of carbon dots (CDs), elucidating how core size, surface chemistry, and heteroatom doping dictate their luminescence mechanisms. Special emphasis is placed on engineering NIR‐II emissive CDs for deep‐tissue imaging.
Zekun Yan, Yupeng Liu, Jinyun Tan, Songnan Qu   +3 more
wiley   +1 more source

Prevalence and spectrum of homologous recombination repair mutations in patients with metastatic prostate cancer from India. [PDF]

Oncologist
Baskarane H, Jain R, Divakar MK, Seth A, Nayak B, Bakhshi S, Sahoo RK, Kumar A, Sharma A, Kaushal S, Haresh KP, Hooda V, Vasudeva P, Singh PP, Agarwal R, Vasundhara S, Agarwal N, Batra A.   +17 more
europepmc   +1 more source

PEK14: A Kinesin‐4 Necessary for Male‐Derived Fertility in Arabidopsis thaliana

Cytoskeleton, EarlyView.
ABSTRACT Of the 61 kinesins annotated in Arabidopsis thaliana, many are still without assigned function. Here, we have screened an insertional mutant library of Arabidopsis pollen‐expressed kinesins for fertility defects. Insertional mutants for three kinesins showed a significant reduction in seed set.
Isabella N. Mendes, Norman R. Groves, Jessica Z. Li, Lily N. Thompson, Brian J. Smith, Aman Y. Husbands, Iris Meier   +6 more
wiley   +1 more source

The Potential of DNA Polymerase Theta (POLQ) Inhibitors as Cancer Therapy for Homologous Recombination (HR)-Deficient Tumors. [PDF]

ACS Med Chem Lett
Abdel-Magid AF.
europepmc   +1 more source

Nuclear Entanglement: New Insights Into the Role of Cytoskeleton and Nucleoskeleton in Plant Nuclear Function

Cytoskeleton, EarlyView.
ABSTRACT Of the three types of cytoskeleton known in animals—actin, microtubules, and intermediate filaments—only actin and microtubules exist in plants. Both play important roles in cellular shaping, organelle movement, organization of the endomembrane system, and cell signaling.
Norman R. Groves, Katelyn Amstutz, Lily A. Schumacher, Iris Meier   +3 more
wiley   +1 more source

A comprehensive genomic framework for identifying genes predisposing to homologous recombination repair-deficient breast or ovarian cancer. [PDF]

BJC Rep
Camacho-Valenzuela J, Matis T, Roca C, Cuamatzi Flores JL, Hamel N, Rivera B, Gravel S, Polak P, Robles-Espinoza CD, Foulkes WD.   +9 more
europepmc   +1 more source

In Vivo Cytoskeletal AMPA Receptor Transport Imaging in C. elegans

Cytoskeleton, EarlyView.
ABSTRACT Long‐distance intracellular transport of ionotropic glutamate receptors (iGluRs) is essential for proper excitatory synaptic function underlying learning and memory. Many neuropsychiatric and neurodegenerative conditions have abnormal iGluR transport and trafficking, leading to an intense interest in the mechanisms and factors regulating these
Michaelis A. K., Hoerndli F. J.
wiley   +1 more source

Development of a lactate metabolism signature for predicting homologous recombination repair status in breast cancer. [PDF]

Sci Rep
Lin Y, Jiang L, Hu S, Zhang Y, Luo M.
europepmc   +1 more source

The Influence of Drosophila Spire and Myosin V During Mid‐Oogenesis Is Independent of Their Direct Interaction

Cytoskeleton, EarlyView.
ABSTRACT Cooperativity between cytoskeletal proteins is crucial for spatiotemporal coordination in biological processes, like oogenesis. In mammalian and Drosophila oogenesis, proper assembly and function of actin networks require coordination between actin assembly factors Spire and formins, as well as actin‐associated proteins like myosins and Rab ...
Joseph Y. Ong, Hannah M. Bailey, Emma Carley, Michelle Panzica, Merin Rixen, Neil Billington, Rong Liu, Margot E. Quinlan   +7 more
wiley   +1 more source