Results 181 to 190 of about 345,396 (332)

An Efficient CO2‐Upcycling Platform Based on Engineered Halomonas TD with Enhanced Acetate‐Utilizing Capacity via Adaptive Laboratory Evolution

open access: yesAdvanced Science, EarlyView.
An electrochemical system is designed to convert CO2 into CO2‐derived electrolytes (CDE), mainly containing acetate and formate. The underlying mechanism of acetate metabolism in Halomonas TD80 is explored via ALE. Engineered TD80 produced high‐yield diversified products from CDE.
Chi Wang   +18 more
wiley   +1 more source

Homologous Recombination in Thyroid Tumor Samples. [PDF]

open access: yesInt J Mol Sci
Spirina LV   +4 more
europepmc   +1 more source

Dual Disruption of the Immune Cytokine Spätzle Facilitates Fungal Infection of Diverse Insect Hosts

open access: yesAdvanced Science, EarlyView.
The Toll pathway is essential for insect defense against fungal pathogens. This works reports that fungal parasites employ two divergent virulent effectors to target the Toll receptor ligand Spätzle: a metalloprotease degrading it and a hairpin‐like effector hijacking it to block signal transduction. This dual strategy enables the fungus to kill a wide
Shuangxiu Song   +7 more
wiley   +1 more source

Comprehensive Measurement of Inter‐Individual Variation in DNA Repair Capacity in Healthy Individuals

open access: yesAdvanced Science, EarlyView.
Susceptibility to the health effects of DNA damage depends on a person's ability to repair DNA damage, but DNA repair has been difficult to measure in populations. A functional assay called FM‐HCR is used to measure DNA repair in 6 major pathways across 56 individuals.
Ting Zhai   +7 more
wiley   +1 more source

Emerging Nanozyme Strategies for Precision Breast Cancer Treatment

open access: yesAdvanced Science, EarlyView.
Different types of nanozymes‐mediated chemotherapy, photothermal therapy, immunotherapy, and multiple combined therapies for the effective treatment of breast cancer. Abstract Breast cancer, the most common malignant tumor among women worldwide, poses a significant challenge to public health due to its high incidence and mortality rates.
Jian Zang   +6 more
wiley   +1 more source

Functional characterization of BRCA1 variants of unknown significance using homologous recombination repair assays. [PDF]

open access: yesBreast Cancer Res
Martín-Bejarano P   +6 more
europepmc   +1 more source

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