Results 181 to 190 of about 773,827 (377)
A two-phase approach for detecting recombination in nucleotide sequences
, 2007 Genetic recombination can produce heterogeneous phylogenetic histories within a set of homologous genes. Delineating recombination events is important in the study of molecular evolution, as inference of such events provides a clearer picture of the ...
Beiko, Robert G. +2 more
core
Homologous pairing in genetic recombination: complexes of recA protein and DNA.
, 1979 Takahiro Shibata +3 more
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Advanced Science, EarlyView.This study developed mAb‐5F2, a monoclonal antibody targeting conserved GP4 residues (Q48/I50), which blocks the GP4‐CD163 interaction, resulting in a 78–85% reduction in viral entry. Porcineized 5F2‐pFc prevented mortality in infected piglets, reduced pulmonary viral loads, and minimized lesions. This broad‐spectrum antibody platform overcomes vaccine
Xu Chen +12 more
wiley +1 more source
Homologous recombination of SV4O DNA in COS7 cells occurs with high frequency m a gene dose independent fashion [PDF]
, 1988 W Rommerskirch +3 more
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Advanced Science, EarlyView.Appressoria are specialized penetration structures for many plant pathogenic fungi, demanding precise cell cycle control. This study unveils MoMtg1 as a transcriptional repressor of MoSwi6, orchestrating MoCYC1 expression during turgor‐driven cell cycle progression to enable appressorium‐mediated penetration. Moreover, a small‐molecule inhibitor ZS1619
Xingyu Wang +11 more
wiley +1 more source
Evolutionary Bioinformatics, 2009 Homologous recombination is a pervasive biological process that affects sequences in all living organisms and viruses. In the presence of recombination, the evolutionary history of an alignment of homologous sequences cannot be properly depicted by a ...
Bastien Boussau +2 more
doaj +2 more sources
Stimulation of recombination between homologous sequences on plasmid DNA and chromosomal DNA in Escherichia coli by N-acetoxy-2-acetylaminofluorene. [PDF]
, 1984 C Luisi-DeLuca +2 more
openalex +1 more source
Mixed Lineage Kinase Domain‐Like Protein (MLKL): From Mechanisms to Therapeutic Opportunities
Advanced Science, EarlyView.The mixed lineage kinase domain‐like protein (MLKL) acts as the executioner in the necroptosis pathway, transitioning from an inactive to active state through phosphorylation, oligomerization, membrane recruitment, and membrane insertion, ultimately forming membrane hotpots.
Lijuan Xu, Chunlin Zhuang
wiley +1 more source
Advanced Science, EarlyView.This review summarizes recent advances in cGAS‐STING agonist‐based nanotherapeutics for cancer combination therapy. It explores nanoparticle‐mediated delivery strategies, underlying molecular mechanisms, and combinatorial applications with chemotherapy, radiotherapy, targeted therapy, phototherapy, sonodynamic therapy, and immunotherapy.
Zhaomeng Wang +3 more
wiley +1 more source
Homologous Recombination and the Repair of Double-Strand Breaks During Cotransformation of Dictyostelium discoideum [PDF]
, 1988 Kenneth Katz, David I. Ratner
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