Homologous pairing in genetic recombination: complexes of recA protein and DNA.
Takahiro Shibata+3 more
openalex +1 more source
Homologous recombination can restore normal immunoglobulin production in a mutant hybridoma cell line. [PDF]
Mark D. Baker+3 more
openalex +1 more source
Abstract Liver cancer stem cells (CSCs) account for tumor initiation, heterogeneity and therapy resistance. However, the role of small nucleolar RNAs (snoRNAs) in the regulation of liver CSCs remains largely unclear. Here, this work identifies a conserved H/ACA box snoRNA SNORA74A which is highly expressed in liver CSCs.
Ziheng Zhou+12 more
wiley +1 more source
FOXM1 maintains mitochondrial bioenergetic function by inhibiting MKRN1‐mediated ubiquitination of LKB1 in cardiomyocytes. Loss of FOXM1 in cardiomyocytes results in upregulation of MKRN1, which enhances LKB1 ubiquitination and disrupts AMPK signaling and energy metabolism pathways. Conversely, FOXM1 overexpression preserves mitochondrial bioenergetics
Shuai Song+17 more
wiley +1 more source
Homologous recombination of SV4O DNA in COS7 cells occurs with high frequency m a gene dose independent fashion [PDF]
W Rommerskirch+3 more
openalex +1 more source
ABSTRACT This study aims to elucidate the role of the ZSWIM7 gene in the etiology of infertility, focusing on its potential association with premature ovarian insufficiency and azoospermia. We investigated an 18‐year‐old female patient who presented with primary amenorrhea, hypoplasia of the uterus and ovaries, Tanner stage II breast and pubic hair ...
Denise M. Christofolini+8 more
wiley +1 more source
Homologous sequences other than insertion elements can serve as recombination sites in plasmid drug resistance gene amplification [PDF]
Brian C. Peterson, R H Rownd
openalex +1 more source
Research advancements and evaluation of multifactor‐induced murine models for gastric cancer
Murine models for gastric cancer. Abstract As one of the most prevalent gastrointestinal malignancies in humans, gastric cancer (GC) is often detected at an advanced stage, resulting in a poor prognosis and ranking it the fifth leading cause of cancer‐related deaths.
Yiqing Wang+5 more
wiley +1 more source
Stimulation of recombination between homologous sequences on plasmid DNA and chromosomal DNA in Escherichia coli by N-acetoxy-2-acetylaminofluorene. [PDF]
C Luisi-DeLuca+2 more
openalex +1 more source
A two-phase approach for detecting recombination in nucleotide sequences
Genetic recombination can produce heterogeneous phylogenetic histories within a set of homologous genes. Delineating recombination events is important in the study of molecular evolution, as inference of such events provides a clearer picture of the ...
Beiko, Robert G.+2 more
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