Results 271 to 280 of about 651,783 (359)

Limited association between HRR gene alterations and HRD in molecular tumor board cancer samples: Who should be tested for HRD?

International Journal of Cancer, EarlyView.
What's New? Currently, no published data on homologous recombination deficiency (HRD) testing in the setting of molecular tumor boards exist. This study in a cohort of 237 patients encompassing 24 different tumor entities assessed by a molecular tumor board shows that inactivating alterations of BRCA1/2 are not always associated with an elevated ...
Christoph Schubart, Lars Tögel, Maria Giulia Carta, Philip Hetzner, Lina Helbig, Charlotte Zaglas, Maria Ziegler, Robert Stöhr, Annett Hölsken, Juliane Hoyer, Fulvia Ferrazzi, Clemens Neufert, Sebastian Lettmaier, Marianne Pavel, Henriette Golcher, Sarina K. Mueller, Florian Fuchs, Carla E. Schulmeyer, Matthias W. Beckmann, Bernd Wullich, Abbas Agaimy, Andre Reis, Arndt Hartmann, Norbert Meidenbauer, Silvia Spoerl, Florian Haller, Evgeny A. Moskalev   +26 more
wiley   +1 more source

Boosting CRISPR-Cas9 efficiency through enhanced homologous recombination. [PDF]

Mol Ther Nucleic Acids
Kim SH, Yoon S, Kim KP.
europepmc   +1 more source

Coupling of Homologous Recombination and the Checkpoint by ATR.

Molecules and Cells, 2017
R. Buisson, Joshi Niraj, Amélie Rodrigue, Chu Kwen Ho, J. Kreuzer, T. Foo, Émilie J.-L. Hardy, G. Dellaire, W. Haas, B. Xia, J. Masson, L. Zou   +11 more
semanticscholar   +1 more source

Promotion of DNA end resection by BRCA1-BARD1 in homologous recombination. [PDF]

Nature
Salunkhe S, Daley JM, Kaur H, Tomimatsu N, Xue C, Raina VB, Jasper AM, Rogers CM, Li W, Zhou S, Mojidra R, Kwon Y, Fang Q, Ji JH, Badamchi Shabestari A, Fitzgerald O, Dinh H, Mukherjee B, Habib AA, Hromas R, Mazin AV, Wasmuth EV, Olsen SK, Libich DS, Zhou D, Zhao W, Greene EC, Burma S, Sung P.   +28 more
europepmc   +1 more source

Construction of Reporter Phage T4::Nluc and Its Application in the Detection of Escherichia coli in Urinary Tract Infections

iLABMED, EarlyView.
A reporter phage T4::Nluc was constructed using the CRISPR/Cas9 system combined with homologous recombination and was applied for the detection of clinical Escherichia coli in urinary tract infections (UTIs). T4::Nluc exhibited superior sensitivity and specificity, and had a short detection time, making it a powerful tool for diagnosing UTIs.
Zhiyun Hao, Minwei Li, Qiang Zhao, Liye Wang, Ting Liu, Chi Wang, Chengbin Wang   +6 more
wiley   +1 more source

Comprehensive analysis of the mitochondrial genome of <i>Iris domestica</i> emphasizing multichromosomal organization and repeat-mediated homologous recombination. [PDF]

Front Plant Sci
Ouyang L, Li X, Wang R, Chen Y, Wang S, Wang J, Tian Y.   +6 more
europepmc   +1 more source

Distribution of exchanges upon homologous recombination of exogenous DNA in Xenopus laevis oocytes.

, 1994
Dana Carroll, Chris W. Lehman, S Jeong-Yu, Paul R. Dohrmann, Renee J. Dawson, Jonathan K. Trautman   +5 more
openalex   +2 more sources

Homologous Recombination

Definitions, 2019
Robert G. Lloyd, K. Brooks
semanticscholar   +1 more source

A human skin microbiome reference catalog and the skin microbial landscape of plateau adults

iMetaOmics, EarlyView.
Understanding the skin microbiome is crucial for elucidating its role in health and disease. However, comprehensive studies on the genetic and functional diversity of the skin microbiome in individuals living in extreme environments remain scarce. This work explores the unique characteristics and functional adaptations of the plateau skin microbiome ...
Yi Liu, Zhiming Li, Chao Zhang, Bo Li, Weiwei Jiang, Hang Li, Lei Zhang, Hefu Zhen, Shujun Bao, Xiong Li, Yinuo Liu, Xianzhen Chen, Jinxia Du, Jingjing Xia, Jiucun Wang, Ruijin Guo, Yuzhe Sun, Bo Pan, Wenzhi Lei, Liang Xiao, Jin Zhao, Xin Jin, Wenwei Zhang, Xiaogang Liu, Jian Wang, Min Chen, Wanqing Liao, Wenjie Fang, Chao Nie, Weihua Pan   +29 more
wiley   +1 more source

Multifaceted roles of H2B mono-ubiquitylation in D-loop metabolism during homologous recombination repair. [PDF]

Nucleic Acids Res
Hung SH, Liang Y, Heyer WD.
europepmc   +1 more source