Results 291 to 300 of about 766,679 (374)
What do the results of this study add? We expanded the clinical phenotype spectrum of fetuses with 16p13.11 deletion and duplication and conducted a preliminary evaluation of prenatal ultrasound findings in conjunction with postnatal clinical phenotypes. The primary manifestations observed in fetuses with 16p13.11 deletion and duplication are likely to
Xiaojin Luo+9 more
wiley +1 more source
PARP inhibitors elicit a cellular senescence mediated inflammatory response in homologous recombination proficient cancer cells. [PDF]
Kamii M+13 more
europepmc +1 more source
Abstract Affinity photolabeling is a smart method to study noncovalent and transient interactions and provide a submolecular picture of the contacts between interacting partners. In this review, we will focus on the identification of peptide partners using photoaffinity labeling coupled to mass spectrometry in different contexts such as in vitro with a
Astrid Walrant, Emmanuelle Sachon
wiley +1 more source
HMCES corrupts replication fork stability during base excision repair in homologous recombination-deficient cells. [PDF]
Peña-Gómez MJ+9 more
europepmc +1 more source
Lysobacter antibioticus OH13 and its antibiotic myxin effectively control rice bacterial leaf streak (BLS) under greenhouse conditions and in field trials. OH13 alters the rhizosphere microbiome, enriching beneficial bacteria. Myxin production was boosted 3.19‐fold via mutagenesis and optimization, highlighting the potential of OH13 as a sustainable ...
Junjing Chen+5 more
wiley +1 more source
Germline variants analysis of Chinese breast cancer patients reveals numerous alterations in homologous recombination genes. [PDF]
Jiang Z+8 more
europepmc +1 more source
Poly(ADP‐ribose) polymerase 1 (PARP‐1) is vital for DNA repair. A computational workflow integrating AI‐driven virtual screening (TransFoxMol, KarmaDock, AutoDock Vina) and molecular dynamics identified novel PARP‐1 inhibitors with promising efficacy and minimized side effects.
Guan Wang+3 more
wiley +1 more source
Salt-inducible kinase 2 confers radioresistance in colorectal cancer by facilitating homologous recombination repair. [PDF]
Meng Y+8 more
europepmc +1 more source