Results 301 to 310 of about 137,826 (378)

Unravelling the molecular basis of PARP inhibitor resistance in prostate cancer with homologous recombination repair deficiency [PDF]

Nabila Zaman, Atar Singh Kushwah, Anagha Badriprasad, Goutam Chakraborty   +3 more
openalex   +1 more source

Cellular Mechanism and Key Insights in Allergen Immunotherapy for Allergic Rhinitis

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Allergic rhinitis (AR) arises from immune responses mediated by immunoglobulin E (IgE) to inhaled allergens, representing one of the most prevalent chronic conditions worldwide. Although AR may not be a serious ailment, it holds clinical relevance as it underpins numerous complications, serves as a major risk factor for suboptimal asthma ...
Zhe Wang, Teng‐Fei Li, Tian‐Yu Wang, Huan‐Hai Liu   +3 more
wiley   +1 more source

Genomic and transcriptomic data reveal molecular differences between homologous recombination deficiency subgroups in Chinese ovarian cancer patients. [PDF]

Hum Genomics
Wang H, Zhao W, Zhou W, Wang N, Li Y, Qin K, Jia J, Wang J, Song C, Yu Y, Zhang F, Cui X, Zhao L, Luo H, Zhang Z.   +14 more
europepmc   +1 more source

Genetic engineering for SIT application: a fruit fly‐focused review

Insect Science, EarlyView.
Abstract Sterile insect technique (SIT) has become a key component of efficient pest control. Fruit fly pests from the Drosophilidae and Tephritidae families pose a substantial and overwhelmingly increasing threat to the agricultural industry, aggravated by climate change and globalization among other contributors.
Serafima Davydova, Danheng Yu, Angela Meccariello   +2 more
wiley   +1 more source

Molecular mechanisms of sex determination in Lepidoptera: current status and perspectives

Insect Science, EarlyView.
The genetic basis of sex determination in Lepidoptera was discovered in 2014 in the silkworm Bombyx mori. In this model species, the W chromosome‐derived small piRNA called Fem piRNA downregulates the expression of a Z‐linked gene, Masculinizer (Masc), which leads to the default female‐specific splicing of the doublesex gene (dsxF) and thus to female ...
František Marec, Atsuo Yoshido, Arjen E. van′t Hof   +2 more
wiley   +1 more source

Homologous recombination deficiency testing in ovarian cancer: the diagnostic experience of a referral Italian institution. [PDF]

Pathologica
Pepe F, Russo G, Cefaliello A, Lamia MR, Buonaiuto R, Crimaldi G, Scimone C, Palumbo L, Roscigno G, Parente P, De Finis MC, Fiordelisi F, Marchetti C, Giampaolino P, De Angelis C, Bianco R, Troncone G, Malapelle U.   +17 more
europepmc   +1 more source

Neoclassical development of genetic sexing strains for insect pest and disease vector control

Insect Science, EarlyView.
The sterile insect technique has been effectively used for decades, and an important component is the availability of sex separation systems, in particular genetic sexing strains. Classical approaches, such as irradiation‐induced chromosomal translocations, have yielded stable strains for species like the Mediterranean fruit fly.
Giovanni Petrucci, Maria‐Eleni Gregoriou, Philippos Aris Papathanos, Marc F. Schetelig, Zhijian Tu, Kostas Bourtzis   +5 more
wiley   +1 more source

The impact of homologous recombination deficiency on the prognosis of epithelial ovarian cancer. [PDF]

Clin Transl Med
Su H, Wang Y, Chao X, Wu H, You Y, Zhao S, Wang F, Sun B, Zhang Z, Wu M, Zhao Z, Li L.   +11 more
europepmc   +1 more source

Data Sheet 4_EXO1 overexpression induces homologous recombination deficiency and enhances PARP inhibitor sensitivity in ER-positive breast cancer: modulation by N4BP2L2-Mediated restoration.pdf

Runa Sugiyama (22617761), Anna S. Sedukhina (22617764), Eri Sato (3353912), Ayako Yamaura (22617770), Kimino Minagawa (13006248), Sookhee Pae (22617773), Ena Imai (22617776), Ankita Chawla (11652879), Ziran Xu (3226602), Mihika Chakraborty (22617779), Satori Gonoi (22617815), Jotaro Yamaoka (22617818), Kazuo Yudo (22617821), Koichiro Tsugawa (697601), Ko Sato (697604)   +14 more
openalex   +1 more source