Results 51 to 60 of about 80,852 (330)
Joint Estimates of Heterozygosity and Runs of Homozygosity for Modern and Ancient Samples
Genetics, 2019 Both the total amount and the distribution of heterozygous sites within individual genomes are informative about the genetic diversity of the population they belong to.
Gabriel Renaud +4 more
semanticscholar +1 more source
PLoS ONE, 2017 Domestication and the subsequent selection of animals for either economic or morphological features can leave a variety of imprints on the genome of a population.
D. Purfield +3 more
semanticscholar +1 more source
The footprint of recent and strong demographic decline in the genomes of Mangalitza pigs
Animal, 2019 The Mangalitza pig breed has suffered strong population reductions due to competition with more productive cosmopolitan breeds. In the current work, we aimed to investigate the effects of this sustained demographic recession on the genomic diversity of ...
V.A. Bâlteanu +6 more
doaj +1 more source
BMC Genomics, 2018 While autozygosity as a consequence of selection is well understood, there is limited information on the ability of different methods to measure true inbreeding.
M. Forutan +5 more
semanticscholar +1 more source
Combined linkage and homozygosity for hydranencephaly.
, 2023 Combined linkage and homozygosity for hydranencephaly.
José Suárez Sánchez-Andrade (16426153) +12 more
core +1 more source
Pedigree-Based Description of Danubia Alba Rabbit Breed Lines
AnimalsThe diversity of livestock animal breeds is an integral part of global biodiversity and requires careful management for sustainability and future availability. Avoiding inbreeding is a crucial aspect of mating of breeding animals.
János Posta +5 more
doaj +1 more source
Frontiers in Genetics, 2020 The Norwegian White sheep (NWS) and New Zealand Terminal Sire Composite (NZC) sheep breeds have been developed based on crossing of multiple breeds, mainly of Northern European origin.
Hinayah Rojas Oliveira +8 more
doaj +1 more source
Long runs of homozygosity are reliable genomic markers of inbreeding depression
Trends in Ecology & EvolutionA long-standing goal in ecological, evolutionary, and conservation genetics is to identify genomic correlates of fitness and inbreeding depression. Over the past several years, a growing body of theoretical and empirical work in diverse mammal and bird ...
Christopher C. Kyriazis +2 more
semanticscholar +1 more source
Proceedings of the National Academy of Sciences of the United States of America, 2019 Significance Only ∼5% of individuals infected with Mycobacterium tuberculosis develop clinical TB in their lifetime. We previously reported that homozygosity for the P1104A variant of the TYK2 gene, found in ∼1/600 Europeans and ∼1/5,000 individuals from
G. Kerner +10 more
semanticscholar +1 more source
Association of Hemochromatosis HFE p.C282Y Homozygosity With Hepatic Malignancy.
Journal of the American Medical Association (JAMA), 2020 Importance Hereditary hemochromatosis is predominantly caused by the HFE p.C282Y homozygous pathogenic variant. Liver carcinoma and mortality risks are increased in individuals with clinically diagnosed hereditary hemochromatosis, but risks are unclear ...
J. Atkins +6 more
semanticscholar +1 more source