Results 101 to 110 of about 43,307 (224)
Plant, Cell &Environment, EarlyView.ABSTRACT Surface immune receptors such as flagellin‐sensitive 2 (FLS2) are critical for plant defence, and their accumulation at the plasma membrane is tightly controlled by the endomembrane system. Here, we identify the Arabidopsis thaliana prenylated Rab acceptor PRA1.F3 as a positive regulator required for efficient accumulation of FLS2 at the ...
Sung Hee Jo +4 more
wiley +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend ACE I/D genotype, enzyme activity and integrated physiological adaptations. Upper panel: Conceptual framework linking the ACE I/D polymorphism (left) with circulating/tissue ACE activity (centre; violin plots based on hypothetical data for illustration) and strength/power versus endurance phenotypes (right).
Tórur Sjúrðarson +1 more
wiley +1 more source
Matrix games between full siblings in Mendelian populations.
PLoS ONEWe develop a model that integrates evolutionary matrix game theory with Mendelian genetics. Within this framework, we define the genotype dynamics that describes how the frequencies of genotypes change in sexual diploid populations.
József Garay +4 more
doaj +1 more source
Caenorhabditis elegans as an in vivo model system for human inherited primary arrhythmia syndromes
The Journal of Physiology, EarlyView.Abstract figure legend Most genes involved in inherited primary arrhythmia syndromes (IPAS) are conserved in Caenorhabditis elegans, where genetic manipulation enables functional characterization of variants, identification of regulatory proteins, and in vivo drug testing.
Antoine Delinière +6 more
wiley +1 more source
Neuropsychopharmacology Reports, Volume 46, Issue 3, September 2026.In our exploratory hypothesis‐generating study using patients with postoperative pain and cancer pain, for rs10781468 in the GNAQ gene, the minor allele was associated with reduced opioid consumption and an increased pain threshold. ABSTRACT Background G protein–coupled receptors, the largest class of cell surface receptors, are ubiquitously expressed ...
Hiroaki Owada +15 more
wiley +1 more source
American Journal of Medical Genetics Part A, Volume 200, Issue 7, Page 1691-1695, July 2026.ABSTRACT Wilson disease (WD) is an autosomal recessive disorder of copper metabolism caused by ATP7B mutations. Diagnosis is usually straightforward in symptomatic patients, but can be challenging in children and adolescents with mild liver disease, borderline urinary copper excretion, or inconclusive genetic findings.
Emanuele Nicastro +10 more
wiley +1 more source
Alzheimer's &Dementia, Volume 22, Issue 7, July 2026.Abstract INTRODUCTION Obstructive sleep apnea (OSA) is a potential risk factor for cognitive impairment and dementia; however, its contribution in midlife and interactions with APOE ε4 remain unclear. METHODS Participants were 2795 cognitively unimpaired, middle‐aged adults enrolled in the Healthy Brain Project. OSA status was determined by self‐report.
Gabriel T. Abdelmessih +4 more
wiley +1 more source
Evidence of APOE4‐related brain vulnerabilities in verbal memory systems in midlife women
Alzheimer's &Dementia, Volume 22, Issue 7, July 2026.Abstract INTRODUCTION Women carrying the apolipoprotein E4 (APOE4) allele have a greater risk of Alzheimer's disease (AD) from ages 65‐75 years compared to men, yet the effects of APOE4 on cognitive and neuroimaging outcomes among midlife women remain poorly understood.
Katrina A. Wugalter +6 more
wiley +1 more source
Genetic Variability in OXTR Polymorphism and Infant Reactivity to Ostracism Experiences
Developmental Psychobiology, Volume 68, Issue 4, July 2026.ABSTRACT The oxytocin system is central to regulating social behaviors, with genetic variations in the oxytocin receptor gene (OXTR), particularly the rs53576 single nucleotide polymorphism (SNP), linked to individual differences in emotional reactivity and social cognition. GG genotype carriers typically show heightened sensitivity to social dynamics,
Testa Alessia +6 more
wiley +1 more source
Ecology and Evolution, Volume 16, Issue 7, July 2026.This study demonstrated multiple paternity in the potato cyst nematode Globodera pallida: all females were polyandrous. Moreover, the female mating rate with different males appeared to remain stable, i.e., an average of seven fathering males, throughout the adaptation process to a masculinizing potato resistance.
Magali Esquibet +5 more
wiley +1 more source