Results 111 to 120 of about 1,600,619 (301)

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Honor y clase: una producción violenta de masculinidades honorables del narcotráfico y la narcocultura en México

open access: yesA&H, 2021
El narcotráfico y la narcocultura en México repercuten en millones de personas y las masculinidades intervienen en la dinámica de estos fenómenos. El objetivo de esta investigación consistió en comprender cómo las nociones de clase y honor producen ...
Marco Alejandro Núñez-González
doaj  

Stolen Valor & the First Amendment: Does Trademark Infringement Law Leave Congress an Opening? [PDF]

open access: yes, 2012
This paper elaborates an argument the authors presented in an amicus brief filed in United States v. Alvarez, the Stolen Valor case. The paper contends that Congress could constitutionally protect the Congressional Medal of Honor as a collective ...
Greabe, John M., Richey, Susan
core   +2 more sources

Cosmological singularity

open access: yes, 2009
The talk at international conference in honor of Ya. B. Zeldovich 95th Anniversary, Minsk, Belarus, April 2009. The talk represents a review of the old results and contemporary development on the problem of cosmological singularity.Comment: to appear in ...
Belinski, V.
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Alice in Wonderland for G4G13 [PDF]

open access: yes, 2017
Each of the ten different letters in the title is used exactly three times to form the words in the circles. Martin Gardner\u27s famous work The Annotated Alice was first published in 1960 and we honor him in this ...
Estroff, Todd Wilk   +2 more
core   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Subordinación remunerada y autonomía económica: modalidades de especialización laboral de africanos y sus descendientes libres en la ciudad de La Plata, siglo XVII

open access: yesFronteras de la Historia, 2020
El ordenamiento de la mano de obra llevado a cabo por Francisco de Toledo en el virreinato del Perú (1574) impuso para los africanos y sus descendientes libres la obligación de asentarse con amos conocidos, bajo subordinación remunerada, con el objetivo ...
Dina Camacho
doaj  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

open access: yesMolecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

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