Experimental Challenge of Atlantic Cod (Gadus morhua) with a Brucella pinnipedialis Strain from Hooded Seal (Cystophora cristata). [PDF]
PLoS ONE, 2016 Pathology has not been observed in true seals infected with Brucella pinnipedialis. A lack of intracellular survival and multiplication of B. pinnipedialis in hooded seal (Cystophora cristata) macrophages in vitro indicates a lack of chronic infection in
Ingebjørg Helena Nymo +6 more
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Entry and elimination of marine mammal Brucella spp. by hooded seal (Cystophora cristata) alveolar macrophages in vitro. [PDF]
PLoS ONE, 2013 A high prevalence of Brucellapinnipedialis serology and bacteriology positive animals has been found in the Northeast Atlantic stock of hooded seal (Cystophoracristata); however no associated gross pathological changes have been identified. Marine mammal
Anett K Larsen +4 more
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Transcriptomes of Clusterin- and S100B-transfected neuronal cells elucidate protective mechanisms against hypoxia and oxidative stress in the hooded seal (Cystophora cristata) brain [PDF]
BMC Neuroscience, 2022 Background The hooded seal (Cystophora cristata) exhibits impressive diving skills and can tolerate extended durations of asphyxia, hypoxia and oxidative stress, without suffering from irreversible neuronal damage. Thus, when exposed to hypoxia in vitro,
Gerrit A. Martens +4 more
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Entrance and survival of Brucella pinnipedialis hooded seal strain in human macrophages and epithelial cells. [PDF]
PLoS ONE, 2013 Marine mammal Brucella spp. have been isolated from pinnipeds (B. pinnipedialis) and cetaceans (B. ceti) from around the world. Although the zoonotic potential of marine mammal brucellae is largely unknown, reports of human disease exist.
Anett K Larsen +4 more
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Transcriptome Analysis Identifies Key Metabolic Changes in the Hooded Seal (Cystophora cristata) Brain in Response to Hypoxia and Reoxygenation. [PDF]
PLoS ONE, 2017 The brain of diving mammals tolerates low oxygen conditions better than the brain of most terrestrial mammals. Previously, it has been demonstrated that the neurons in brain slices of the hooded seal (Cystophora cristata) withstand hypoxia longer than ...
Mariana Leivas Müller Hoff +4 more
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A review of
Veterinary Research, 2011 Brucella spp. were isolated from marine mammals for the first time in 1994. Two novel species were later included in the genus; Brucella ceti and Brucella pinnipedialis, with cetaceans and seals as their preferred hosts, respectively. Brucella spp.
Nymo Ingebjørg H +2 more
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The eyes of the deep diving hooded seal (Cystophora cristata) enhance sensitivity to ultraviolet light [PDF]
Biology Open, 2015 The mammalian visual range is approximately 400–700 nm, although recent evidence suggests varying ultraviolet (UV) extensions in diverse terrestrial species.
Chris Hogg +6 more
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Transcriptomes Suggest That Pinniped and Cetacean Brains Have a High Capacity for Aerobic Metabolism While Reducing Energy-Intensive Processes Such as Synaptic Transmission [PDF]
Frontiers in Molecular Neuroscience, 2022 The mammalian brain is characterized by high energy expenditure and small energy reserves, making it dependent on continuous vascular oxygen and nutritional supply. The brain is therefore extremely vulnerable to hypoxia. While neurons of most terrestrial
Cornelia Geßner +5 more
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Elevated antioxidant defence in the brain of deep-diving pinnipeds [PDF]
Frontiers in Physiology, 2022 While foraging, marine mammals undertake repetitive diving bouts. When the animal surfaces, reperfusion makes oxygen readily available for the electron transport chain, which leads to increased production of reactive oxygen species and risk of oxidative ...
Gerrit A. Martens +3 more
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Potential for flexible lactate shuttling between astrocytes and neurons to mitigate against diving-induced hypoxia [PDF]
Frontiers in NeuroanatomyFor most non-diving mammals, lack of O2 (hypoxia) has detrimental effects on brain function. Seals, however, display a series of systemic, cellular, and molecular adaptations that enable them to tolerate repeated episodes of severe hypoxia.
Chiara Ciccone +7 more
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