Results 21 to 30 of about 150,727 (214)
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin +2 more
wiley +1 more source
Il finanziamento Venture Capital: implicazioni della definizione di Piccola e Media Impresa
Argomenti: Rivista di Economia, Cultura e Ricerca Sociale, 2021 Questo lavoro analizza la definizione di Piccola e Media Impresa (PMI) della Commissione Europea e la confronta con definizioni affini adottate dalle organizzazioni internazionali. L’analisi approfondisce come la definizione dei termini di partecipazione
Andrea Bellucci, Gianluca Gucciardi
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FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Drivers for Clustering and Inter-Project Collaboration—A Case of Horizon Europe Projects
Administrative SciencesThis paper investigates the drivers and dynamics of clustering and inter-project collaboration within the framework of the Horizon Europe and Horizon 2020 projects.
Takwa Benissa, Anish Patil
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Conceptual Design of a Modular Floating Multi-Purpose Island
Frontiers in Marine Science, 2021 The design of a modular floating multi-purpose island inherently involves interaction within a group with a large range of backgrounds such as engineering, architecture, sociology, climate modeling, and more.
Ingo Drummen, Gerrit Olbert
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FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Building knowledge-based economy in the EU: methodological background and policy solutions [PDF]
International Economic Policy, 2018 The purpose of this paper is to highlight some major theoretical concepts, related to the notion of the knowledge-based economy, and to analyze EU policies, aimed at strengthening R&D potential and technologies commercialization of the EU member-states.
Lukasz Jablonski +2 more
doaj +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source