Results 31 to 40 of about 53,467 (254)

Immunoglobulin Depletion and Recovery Following Blinatumomab in Infants With KMT2A‐Rearranged ALL

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Adding blinatumomab to standard chemotherapy for infants with KMT2A‐rearranged acute B‐cell lymphoblastic leukemia (KMT2A‐r B‐ALL) improves outcomes. Although blinatumomab impairs immunoglobulin G (lgG) production, increasing infection susceptibility, IgG recovery remains poorly understood.
Miguel Vieira Martins, Paola de Lorenzo, Rishi S. Kotecha, Andishe Attarbaschi, Gabriele Escherich, Karsten Nysom, Jan Stary, Alina Ferster, Benoit Brethon, Franco Locatelli, Martin Schrappe, Peggy E. Scholte‐van Houtem, Maria G. Valsecchi, Rob Pieters, Inge M. van der Sluis   +14 more
wiley   +1 more source

EU–China research cooperation under a “de-risking” framework: the securitisation of knowledge in EU science policy (2021–2025)

Asian Review of Political Economy
Using developments in EU–China research cooperation between 2021 and 2025 as an empirical window, this article examines how the EU’s de-risking agenda is reconfiguring research governance through the securitisation of knowledge exchange.
Yang Li, Ting Long
doaj   +1 more source

Horizon Europe: Open Science is the 'new' normal

, 2021
Starting from 2021, with the kickoff of the European Commission framework programme Horizon Europe, Open Science is expected to be the modus operandi in science. This presentation, given at the  Åpen forskning: Delta i European Open Science Cloud organised on may 26, 2021 form the Research Council of Norway, is presenting the Open Science strategy of ...
openaire   +4 more sources

Change in Mental Health and Resilience in Childhood Cancer Survivors After Attending a Person‐Centred State‐of‐the‐Art Late Effects Clinic—on Behalf of the PanCareFollowUp Consortium

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Person‐centred follow‐up care based on evidence‐based clinical practice guidelines and providing individualised information should help to inform and reassure survivors about their medical and psychosocial situation and provide treatment and support where needed.
Gisela Michel, Mieke Rijken, Marietta Kokla, Charlotte Sleurs, Jurgen Lemiere, Line Elmerdahl Frederiksen, Luzius Mader, Cecilia Follin, Sara Oberti, Jeanette Falck Winther, Selina R. van den Oever, Leontien C. M. Kremer, Helena J. H. van der Pal, Peter Spreeuwenberg, Eline Bouwman, Jeroen te Dorsthorst, Samira Essiaf, Elizabeth A. M. (Lieke) Feijen, Hannah Gsell, Riccardo Haupt, Maria van Helvoirt, Rosella P. M. G. Hermens, Lars Hjorth, Tomas Kepak, Katerina Kepakova, Anita Kienesberger, Monica Muraca, Marleen Renard, Carina Schneider, Roderick Skinner, Anne Uyttebroeck, Deveny Vanrusselt, Sabine Verschueren, Jacqueline Loonen, Saskia M. F. Pluijm, Katharina Roser, the PanCareFollowUp consortium   +36 more
wiley   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin, Berrak Itır Aylı, Nüket Paksoy   +2 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Institutional leadership and regional contagion: Causal drivers of European research performance in the education sector

Management şi Marketing
Participation in the European Union’s Framework Programs such as Horizon Europe has become a strategic priority for higher and secondary education (HES) institutions, yet the underlying determinants of funding success remain difficult to disentangle due ...
Saftiuc Bogdan-Paul, Proșcanu Cosmin Adrian, Teodorescu Cosmin   +2 more
doaj   +1 more source

Open Science and Research Data Management in Horizon Europe

Journal of Research Management and Administration
What is new? Open Science is considered the “modus operandi” within the EU’s Horizon Europe research funding programme. However, researchers and institutions often struggle to navigate its legal provisions and practical requirements on open ...
Daniel Spichtinger
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Sustainable Urban Areas for 2030 in a Post-COVID-19 Scenario: Focus on Innovative Research and Funding Frameworks to Boost Transition towards 100 Positive Energy Districts and 100 Climate-Neutral Cities

Energies, 2021
Cities generate about 85% of the EU’s GDP. As such, they are key players in shaping and providing technological and social innovations but also environmental impact.
Paola Clerici Maestosi, Maria Beatrice Andreucci, Paolo Civiero   +2 more
doaj   +1 more source