Results 61 to 70 of about 2,176,365 (198)

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

A report from a conference jointly organised by the European Academy of Cancer Sciences and the Pontifical Academy of Sciences, The Vatican, November 16–17, 2018

open access: yesMolecular Oncology, 2019
Cancer is a massive challenge with a significant impact on society, healthcare systems, the economy and an increasing number of patients and their families.
European Academy of Cancer Sciences
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Science Diplomacy in Horizon Europe Program: Taiwan’s TSMC as an Example for strengthening EU-Taiwan Relations [PDF]

open access: yesRevista UNISCI
In this article, the author first introduces Taiwan's science diplomacy and its initial involvement in the EU's Horizon Europe programme, the EU's current flagship initiative for scientific innovation.
Adolfo Yinshi Wu
doaj  

Biodiversity Genomics Europe (BGE) Project – Abridged Grant Proposal [PDF]

open access: yesResearch Ideas and Outcomes
The Biodiversity Genomics Europe (BGE) Project has the overarching aim of accelerating the use of genomic science to enhance understanding of biodiversity, monitor biodiversity change, and guide interventions to address its decline.
Dimitris Koureas   +68 more
doaj   +3 more sources

A Semantic Mapping of Food Systems Research and Innovation in Horizon Europe: Insights from FOOD2030 Pathways and Food Systems Thematic Clustering [PDF]

open access: yes
openAs the first strategic plan of Horizon Europe (HE)—the European Union’s flagship Framework Program for Research and Innovation (R&I)— concluded in December 2024, it became essential to assess its alignment with key policy frameworks.
NERI, FEDERICO
core  

Funding Research in Horizon 2020: Europe's Most Valuable Strategic Resource

open access: yes, 2016
Science Europe expresses strong concern that the research funding budget be maximised in Horizon 2020 so that Europe can fully realise its target of becoming a smart, sustainable and inclusive economy.
Science Europe
core   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

Clinical Impact of NOTCH3 Variant Location After First Stroke in CADASIL

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Despite its monogenic origin, Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy exhibits marked variability in clinical expression and severity. Variants in the NOTCH3 gene, within epidermal growth factor‐like repeat domains 1–6 or 7–34, are known to influence disease onset, but their impact ...
Léa Aguilhon   +5 more
wiley   +1 more source

Quantitative MRI Uncovers Subtle Cortical Damage in Myelin Oligodendrocyte Glycoprotein Antibody‐Associated Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine whether myelin‐sensitive quantitative MRI reveals microstructural abnormalities in normal‐appearing cortex (NACtx) in myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), indicating that conventional MRI underestimates remission residual cortical injury.
Valentina Camera   +20 more
wiley   +1 more source

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