Results 51 to 60 of about 1,644,938 (307)

Concepción didáctica para la disciplina contabilidad en el ciclo básico de la carrera Contabilidad y Finanzas de la Universidad de Pinar Del Río

open access: yesRevista Ciencias Pedagógicas e Innovación, 2017
La investigación está dirigida a proponer una concepción didáctica para el proceso de enseñanza-aprendizaje durante el ciclo básico para los estudiantes de primero y segundo año de la carrera de Contabilidad y Finanzas de la Universidad de Pinar del Río,
Reinaldo Castaño de Armas   +2 more
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Upstream horizontal mergers, bargaining, vertical contracts [PDF]

open access: yes, 2005
Contrary to the seminal paper of Horn and Wolinsky (1988), we demonstrate that upstream firms, which sell their products to competing downstream firms, do not always have incentives to merge horizontally. In particular, we show that when bargaining takes
Milliou, Chrysovalantou   +1 more
core   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

On the plastic collapse of horizontal saddle supported storage vessels [PDF]

open access: yes, 2003
The present paper summarises a comprehensive programme of work on collapse loads of horizontal cylindrical saddle supported storage vessels. A programme of tests was conducted on 40 model vessels that included both welded and loose saddles.
Tooth, A.S., Spence, J., Nash, D.H.
core   +2 more sources

Die großräumige Höhenströmung in der Hauptregenzeit feuchter und trockener Jahre über dem südamerikanischen Altiplano

open access: yesMeteorologische Zeitschrift, 1992
Auf der Basis täglicher Gitternetzfelder der horizontalen Windkomponenten im 200 hPa-Niveau für den Zeitraum 1968-1985 werden die großräumigen Höhenströmungsverhältnisse in der Hauptregenzeit (Januar bis März) der regenreichsten bzw.
J. Jacobeit
doaj   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Year-round correlation between mass and copulation duration in forest millipedes [PDF]

open access: yesArthropods, 2020
Correlates of diplopod size include diet, copulation duration, energy expense of copulation, oxygen consumption, precipitation, sex and temperature. Sexual Size Dimorphism (SSD) in the diplopod genus Centrobolus has a positive correlation with body size ...
Mark Cooper
doaj  

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

open access: yesMolecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler   +3 more
wiley   +1 more source

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