Results 121 to 130 of about 384,646 (364)
Engineering Assembloids to Mimic Graft‐Host Skeletal Muscle Interaction
Advanced Healthcare Materials, EarlyView.This study develops a graft‐host skeletal muscle assembloid model combining neuromuscular organoids with tissue‐engineered constructs. Pre‐seeding decellularized muscles with myogenic cells enhances cell migration and axon invasion from the organoid. The model exhibits regenerative capacity following acute damage, advancing the understanding of human ...
Lucia Rossi +13 more
wiley +1 more source
Evolution of bacterial genomes under horizontal gene transfer [PDF]
arXiv, 2011 Unraveling the evolutionary forces shaping bacterial diversity can today be tackled using a growing amount of genomic data. While the genome of eukaryotes is highly stable, bacterial genomes from cells of the same species highly vary in gene content. This huge variation in gene content led to the concepts of the distributed genome of bacteria and their
arxiv
Horizontal gene transfer contributes to plant evolution : the case of Agrobacterium T-DNAs [PDF]
, 2017 Horizontal gene transfer (HGT) can be defined as the acquisition of genetic material from another organism without being its offspring. HGT is common in the microbial world including archaea and bacteria, where HGT mechanisms are widely understood and ...
Gheysen, Godelieve +2 more
core +1 more source
Advanced Healthcare Materials, EarlyView.The scaffold‐free Anchored Cell Sheet Engineering platform is used to create three‐dimensional (3D) in vitro models of skeletal muscle tissue that replicate key features of Duchenne and Myotonic dystrophies. These personalized tissue models, validated by histological, immunostaining, and proteomics analyses, accurately mimic disease phenotypes and ...
Alireza Shahin‐Shamsabadi +1 more
wiley +1 more source
Counting and sampling gene family evolutionary histories in the duplication-loss and duplication-loss-transfer models [PDF]
arXiv, 2019 Given a set of species whose evolution is represented by a species tree, a gene family is a group of genes having evolved from a single ancestral gene. A gene family evolves along the branches of a species tree through various mechanisms, including - but not limited to - speciation, gene duplication, gene loss, horizontal gene transfer.
arxiv
Morphogenic Growth 3D Printing
Advanced Materials, EarlyView.I additive manufacturing process exploits the spatial propagation of a polymerization reaction front to produce 3D polymer parts 10× faster and 1000× more energy efficient than the fastest stereolithography. In contrast with existing 3D printing, this morphogenic process is inspired by biological “growth and form” due to the self‐directed propagation ...
Yun Seong Kim +10 more
wiley +1 more source
Normalizing Kernels in the Billera-Holmes-Vogtmann Treespace [PDF]
arXiv, 2015 As costs of genome sequencing have dropped precipitously, development of efficient bioinformatic methods to analyze genome structure and evolution have become ever more urgent. For example, most published phylogenomic studies involve either massive concatenation of sequences, or informal comparisons of phylogenies inferred on a small subset of ...
arxiv
The Gossip Paradox: why do bacteria share genes? [PDF]
arXiv, 2020 Bacteria, in contrast to eukaryotic cells contain two types of genes: chromosomal genes that are fixed to the cell, and plasmids that are mobile genes, easily shared to other cells. The sharing of plasmid genes between individual bacteria and between bacterial lineages has contributed vastly to bacterial evolution, allowing specialized traits to `jump ...
arxiv
Horizontal gene transfer in human pathogens [PDF]
Critical Reviews in Microbiology, 2013 Horizontal gene transfer has a tremendous impact on the genome plasticity, adaptation and evolution of bacteria. Horizontally transferred mobile genetic elements are involved in the dissemination of antibiotic resistance and virulence genes, thus contributing to the emergence of novel "superbugs".
openaire +3 more sources
Measuring degradation of transgenic DNA and screening for horizontal gene transfer from GMO-plant material during composting [PDF]
, 2004 The experiments show that composting of GM plant residues greatly increases the rate of degradation of transgenic DNA compared to the rate for plant residues left in the soil.
Magid, Jakob +2 more
core