Results 141 to 150 of about 384,646 (364)
Microbiome, 2018 The ubiquity of horizontal gene transfer in the living world, especially among prokaryotes, raises interesting and important scientific questions regarding its effects on the human holobiont i.e., the human and its resident bacterial communities ...
Ramakrishnan Sitaraman
doaj +1 more source
Advanced Theory and Simulations, EarlyView.This study analyses the electronic structure of five‐electron spherical quantum dots with penetrable confinement potential. Spatial confinement and the influence of potential barrier height give rise to the unique properties of quantum dots. These effects lead to profound changes in their energy spectra and optical properties which play a key role in ...
Yusuf Yakar, Bekir Çakır, Ayhan Özmen
wiley +1 more source
Molecular & Cellular Oncology, 2018 Horizontal gene transfer is known to occur in bacteria and archaea whereas higher organisms including mammals undergo vertical transfer. Our recent results demonstrate horizontal transfer of mitochondrial DNA (mtDNA) from normal host cells to tumor cells
Michael V. Berridge +2 more
doaj +1 more source
Advanced Science, EarlyView.AAV2.7m8 serotype combined with the gfaABC1D promoter targets infection of supporting cells (SCs). AAV2.7m8‐gfaABC1D‐Gjb2 administration to mice results in excessive immune responses. The combination of AAV2.7m8‐gfaABC1D‐Gjb2 with dexamethasone (DEX) shows a synergistic effect and enhances the gene therapy effect in a conditional Cx26 null mice model ...
Xiaohui Wang +8 more
wiley +1 more source
Mathematical modeling of evolution of horizontally transferred genes [PDF]
arXiv, 2005 We describe a stochastic birth-and-death model of evolution of horizontally transferred genes in microbial populations. The model is a generalization of the stochastic model described by Berg and Kurland and includes five parameters: the rate of mutational inactivation, selection coefficient, immigration rate (i.e., rate of arrival of a novel sequence ...
arxiv
Advanced Science, EarlyView.Traditional Chinese Medicine (TCM), while holistic and historically esteemed, faces challenges in “miracle cures” due to slow onset, long cycles, and difficulty controlling quality. This study obtains the active ingredients, glabridin (GLA) and puerarin (PUE), from Ge‐Gen Decoction (GGD), developing a safe and effective drug delivery system, GLA‐PUE ...
Jianhong Qi +7 more
wiley +1 more source
Advanced Science, EarlyView.Iron deficiency reduces monocyte dendritic cell progenitor (MDP) numbers by inhibiting migration and proliferation while promoting apoptosis, subsequently reducing downstream common dendritic cell precursors (CDP) and dendritic cell (DC). Impaired DCs enter the lungs via blood circulation, where reduced antigen presentation impairs T‐cell activation ...
Quanzhong Ren +8 more
wiley +1 more source
Evolution and Horizontal Transfer of dUTPase-Encoding Genes in Viruses and Their Hosts [PDF]
, 1999 Angela M. Baldo, Marcella A. McClure
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Forbidden Time Travel: Characterization of Time-Consistent Tree Reconciliation Maps [PDF]
arXiv, 2017 In the absence of horizontal gene transfer it is possible to reconstruct the history of gene families from empirically determined orthology relations, which are equivalent to event-labeled gene trees. Knowledge of the event labels considerably simplifies the problem of reconciling a gene tree T with a species trees S, relative to the reconciliation ...
arxiv