Low-Frequency Horizontal Transfer of an Element Containing the Chlorocatechol Degradation Genes from Pseudomonas sp. Strain B13 to Pseudomonas putida F1 and to Indigenous Bacteria in Laboratory-Scale Activated-Sludge Microcosms [PDF]
Roald Ravatn+2 more
openalex +1 more source
Overview of the Genetic Deafness Commons (GDC), integrating data from the Chinese Deafness Genetics Consortium (CDGC) and 51 public databases. The GDC provides tools for variant search, functional predictions, and gene‐disease visualization, offering insights into 201 hearing loss genes and facilitating novel gene discovery and clinical applications ...
Hui Cheng+11 more
wiley +1 more source
Modulation of Horizontal Gene Transfer in Pathogenic Bacteria by In Vivo Signals [PDF]
Stephanie F. Mel, John J. Mekalanos
openalex +1 more source
Nanotherapy for Neural Retinal Regeneration
Nanotechnology enhances ophthalmic treatments by improving drug delivery and regenerating ocular tissues, combating vision loss from retinal diseases through innovative nano‐systems. This review outlines ocular anatomy, pathology, immune microenvironment, and barriers, detailing nanocarrier characteristics, classification, and preparation methods, and ...
Chuyao Yu+11 more
wiley +1 more source
Horizontal gene transfer drives extreme physiological change in Haloarchaea [PDF]
The haloarchaea are aerobic, heterotrophic, photophosphorylating prokaryotes, whose supposed closest relatives and ancestors, the methanogens, are CO2-reducing, anaerobic chemolithotrophs. Using two available haloarchaeal genomes we firstly confirmed the methanogenic ancestry of the group and then investigated those individual genes in the haloarchaea ...
arxiv
Evidence of Horizontal Transfer of the Eco O109I Restriction-Modification Gene to Escherichia coli Chromosomal DNA [PDF]
Keiko Kita+5 more
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By investigating auditory hyperexcitability in a mouse model for hereditary deafness, this study identified a subpopulation of afferent neurons of the auditory nerve marked by Otogl expression. Despite their apparently normal hearing, Otogl+/− mice display poor activation of afferent neurons processing loud sounds and an elevation of the middle the ear
Mathilde Gagliardini+24 more
wiley +1 more source
The chromosomal organization of horizontal gene transfer in bacteria
Horizontal gene transfer (HGT) is an important mechanism for genome evolution and adaptation in bacteria. Here, Oliveira and colleagues find HGT hotspots comprising ~ 1% of the chromosomal regions in 80 bacterial species.
Pedro H. Oliveira+3 more
doaj +1 more source
Reconstruction of time-consistent species trees [PDF]
The history of gene families -- which are equivalent to event-labeled gene trees -- can to some extent be reconstructed from empirically estimated evolutionary event-relations containing pairs of orthologous, paralogous or xenologous genes. The question then arises as whether inferred event-labeled gene trees are "biologically feasible" which is the ...
arxiv
Horizontal gene transfer among microbial genomes: new insights from complete genome analysis [PDF]
Jonathan A. Eisen
openalex +1 more source