Results 61 to 70 of about 881,069 (299)
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
FEBS Open Bio, EarlyView.Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
Detection of nanoseismic events related to slope instabilities in the quarry district of Coreno Ausonio (Italy) [PDF]
, 2016 Le cave per l’estrazione di materiale roccioso rappresentano contesti in cui possono aver luogo eventi di instabilità gravitativa causati dalle continue sollecitazioni cui sono soggette le pareti produttive, principalmente connesse alle vibrazioni dovute
FIORUCCI, MATTEO +3 more
core +1 more source
Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina +11 more
wiley +1 more source
Sensors, 2011 Deep displacement observation is one basic means of landslide dynamic study and early warning monitoring and a key part of engineering geological investigation.
Xiong Li +5 more
doaj +1 more source
Cracking the Code: Genotype–Phenotype Correlation Models in Sarcoglycanopathies
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Sarcoglycanopathies are among the most severe limb‐girdle muscular dystrophies (LGMD), though milder presentations have been described. These diseases are primarily caused by missense variants, but the limited predictability of their effect on protein maturation, complex formation, and transport has hindered reliable genotype ...
Leonela Luce +72 more
wiley +1 more source
Movement Disorders in Aicardi–Goutières Syndrome and Response to Immunomodulation
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT This study characterizes movement disorders and treatment responses in seven children with Aicardi–Goutières syndrome (AGS). We retrospectively evaluated motor phenotypes, neuroimaging, and interferon signatures in patients treated with baricitinib or anifrolumab. Spasticity affected all patients, while dystonia was present in 4/7.
Enrique Gonzalez Saez‐Diez +10 more
wiley +1 more source
Nuclear Engineering and Technology, 2017 In order to monitor the pipe thinning caused by flow-accelerated corrosion (FAC) that occurs in coolant piping systems, a shear horizontal ultrasonic pitch-catch waveguide technique was developed for accurate pipe wall thickness monitoring.
Yong-Moo Cheong +2 more
doaj +1 more source
Unrest at Domuyo Volcano, Argentina, detected by geophysical and geodetic data and morphometric analysis [PDF]
, 2019 New volcanic unrest has been detected in the Domuyo Volcanic Center (DVC), to the east of the Andes Southern Volcanic Zone in Argentina. To better understand this activity, we investigated new seismic monitoring data, gravimetric and magnetic campaign ...
Acosta, Gemma +6 more
core +1 more source
Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni +19 more
wiley +1 more source
Monitoring of the water particle velocity field near the seabed under different wave and tidal scenarios: a real case [PDF]
, 2015 Monitoring of water particle velocity on the sea bed is crucial to study morphological shore changes in a coast at intermediate and shallow water depth under progressive surface waves and tidal flow current. Therefore, 3-D particle velocity was monitored
Khan-Mozahedy, A.B.M. +2 more
core +1 more source