Results 111 to 120 of about 886,828 (304)

Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni   +19 more
wiley   +1 more source

Supporting Technology of Shale Gas Horizontal Well Cementing Tool

open access: yesShiyou jixie, 2016
To meet the special requirement of shale gas horizontal well cementing,and to address the issues like difficult casing running in shale gas horizontal well,poor casing centralization in horizontal section,and casing float collar and float shoe close ...
Zhou Zhanyun   +5 more
doaj  

Impact of Plasma p‐tau181 on Cognition, Motor Phenotypes, and Disease Course in ALS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Phosphorylated tau181 (p‐tau181), an Alzheimer's disease biomarker, was recently evaluated in amyotrophic lateral sclerosis (ALS). We investigated plasma p‐tau181 in 202 ALS/ALS‐FTD patients and 94 healthy controls, assessing cognitive performance, motor function, and longitudinal dynamics.
Elisabeth Kasper   +25 more
wiley   +1 more source

Horizontal gene transfer and evolution of antibiotic gene clusters [PDF]

open access: yes
Genome sequencing projects from diverse bacteria and the release of genetically engineered microorganisms make the topic of horizontal gene transfer (HGT) fashionable.
Kallifidas, Dimitrios
core  

Electroencephalographic Normalization as a Biomarker of Clinical Recovery in Down Syndrome Regression Disorder

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Down syndrome regression disorder is a syndrome characterized by subacute loss of cognitive, behavioral, and functional abilities in individuals with Down syndrome. Electroencephalography abnormalities are frequently observed during evaluation, but it remains unclear whether these findings represent a dynamic marker of disease ...
Jonathan D. Santoro   +14 more
wiley   +1 more source

PRODUCTIVITY INDEX IN HORIZONTAL WELL

open access: yes
The work in this project studied the productivity index of horizontal wells in the Mabruk (west Mabruk) oil field. Different aspects of horizontal wells were reviewed; including drilling and completion technologies, limitations and applications ...
Wanis Salem Abdal   +1 more
core   +1 more source

On Single Well Forced Gradient Tracer Tests: Implications of Aquifer Physical Heterogeneity and Tracer Behaviour [PDF]

open access: yes, 2010
Single well forced gradient tracer tests are a potential cost-effective approach to estimate in situ aquifer contaminant fate and transport parameters for use in natural attenuation assessments and remediation schemes.
Barns, Gareth L
core  

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