Results 91 to 100 of about 891,157 (304)
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
FEBS Open Bio, EarlyView.Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
A method for analysing fluid structure interactions on a horizontal axis tidal turbine [PDF]
, 2011 Free stream tidal turbines are rotating bodies in fast flowing tidal currents, and as such are exposed to fluctuating loads from the surrounding fluid.
Nicholls-Lee, R.F. +2 more
core
Key Technologies and Understanding of Shale Gas Horizontal Well Drilling of Well JY10HF
Shiyou jixie, 2019 Well JY10HF is the first exploratory shale gas horizontal well in the Jinfoshan fault slope of Nanchuan. The developed fracture and cave, large dip angle and poor drillability make it easy to be faced with lost circulation, wellbore collapse, inclination
Fan Hua, Long Zhiping
doaj
FEBS Open Bio, EarlyView.Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
Horizontal Equity: New Measures, Unclear Principles [PDF]
Alan Auerbach and Kevin Hassett offer a new measure of horizontal equity (HE) that is designed to overcome deficiencies in prior indexes. There is, however, a fundamental problem that their effort shares with their predecessors' attempts: the underlying ...
Louis Kaplow
core
SELECTING OPTIMAL DESIGN OF A HORIZONTAL WELL BY NUMERICAL MODELING [PDF]
, 2022 Computer aided design of a horizontal well without flush tubes providing optimal operating conditions with regard to varying pressure along horizontal well length, to the presence of deviated and slant segments is considered.
Lyubov G. Korshunova +4 more
core +1 more source
Well spacing optimization technology for coalbed methane horizontal wells
Meitian dizhi yu kantanBackgroundWell spacing design directly affects the resource utilization and exploitation benefits of blocks. Rational well spacing design plays a significant role in the commercial exploitation of coalbed methane (CBM) fields.
Yuting WANG +10 more
doaj +1 more source
FEBS Open Bio, EarlyView.The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
Horizontal Well Drilling Technique for Zahaquan Tight Oil
Shiyou jixie, 2016 To improve the overall tight oil development benefits,the first tight oil horizontal well was deployed in Qinghai Oilfield.But the long drilling period has impacted the tight oil development program with horizontal well.The key reasons of long horizontal
Hu Gui +6 more
doaj