Results 91 to 100 of about 29,662 (265)

ASSESSMENT OF SAFETY OF HORMONAL CONTRACEPTIVES USING PATIENT MEDICAL HISTORY

open access: yesВестник медицинского института «Реавиз»: Реабилитация, врач и здоровье, 2020
According to the National Project ‘Demography,’ cumulative birth rate per 1 woman should increase from 1.62 in 2017 to 1.70 in 2024. From an ethical point of view, the use of hormonal contraceptives is unacceptable due to their abortive effect.
E. A. Lebedeva   +2 more
doaj  

Hydrogel‐based drug delivery systems for intracerebral hemorrhage with therapeutic advances and emerging roles of the bone–brain axis

open access: yesInterdisciplinary Medicine, EarlyView.
Hydrogel‐based drug delivery systems offer a promising approach for treating intracerebral hemorrhage (ICH) by overcoming blood‐brain barrier limitations, enabling precise, sustained release of neuroprotective and anti‐inflammatory agents. These systems enhance treatment efficacy, but challenges remain in biosafety, drug penetration, and scalability ...
Haojun Shi   +18 more
wiley   +1 more source

Non-Contraceptive Benefits of Oral Hormonal Contraceptives

open access: yesInternational Journal of Endocrinology and Metabolism, 2012
It is becoming evident that oral hormonal contraceptives-besides being well established contraceptives-seem to become important medications for many functional or organic disturbances. So far, clinical effectiveness has been shown for treatment as well as prevention of menstrual bleeding disorders and menstrual-related pain symptoms.
openaire   +5 more sources

Tannic Acid Mitigates Monosodium Glutamate‐Induced Cortical Damage by Modulating Synaptic and Calcium‐Related Gene and Protein Expression

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Neurotoxicity induced by excessive glutamatergic signaling is associated with synaptic dysfunction, calcium imbalance, and oxidative stress, which are key molecular events implicated in several neurodegenerative conditions. Monosodium glutamate (MSG), a common flavor enhancer, may exert neurotoxic effects, particularly on synaptic integrity ...
Medine Sibel Karagac   +2 more
wiley   +1 more source

Melanoma Cells Exposed to Clomiphene Citrate Respond With Cell Cycle Arrest and Reduced Invasiveness

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Epidemiological studies have suggested that clomiphene citrate (CC) exposure may increase the risk of malignant melanoma, but mechanisms are unknown. We investigated the effects of CC on melanoma cell line A375. Cells were treated with CC at 2, 20, 200, and 2000 ng/mL, followed by assessment of cell viability and metabolism, cell cycle ...
Thaís S. Ribeiro   +8 more
wiley   +1 more source

Accessory Cavitated Uterine Malformation (ACUM): A Case Series

open access: yesJournal of Clinical Ultrasound, EarlyView.
Accessory cavitated uterine malformation (ACUM) can be misdiagnosed as other uterine pathologies, such as mullerian anomalies, adenomyosis or fibroids. Imaging, particularly gynecological ultrasound plays a fundamental role in identifying this condition.
Luis Felipe Aravena   +8 more
wiley   +1 more source

New Horizons in Male Contraception: Clinical, Cultural and Technological Innovation Aspects

open access: yesSexes
Background/Objectives: The main contraceptive options for men are condoms, vasectomy and coitus interruptus. Clinical and preclinical trials are being conducted to develop a new male contraceptive (NMC), which can be either hormonal or non-hormonal.
Lucca Moisés Santiago Silva   +6 more
doaj   +1 more source

Mapping the subgingival HerBiome and HisBiome over the human healthspan

open access: yesJournal of Periodontology, EarlyView.
Abstract Background Understanding the intricate relationship between sex, age, and the oral microbiome is crucial for deciphering the onset and progression of numerous age‐related oral and systemic diseases. Methods Subgingival plaque was collected from 781 periodontally and systemically healthy females and 160 males spanning 0 to 80 years.
Rahul Nikam   +3 more
wiley   +1 more source

Exploring the association between vitamin C intake and gingival bleeding tendency in healthy, non‑deficient young adults

open access: yesJournal of Periodontology, EarlyView.
Abstract Background The aim of this study is to investigate the relationship between reported vitamin C intake and gingival bleeding severity. Methods In this cross‐sectional study, 336 participants were screened, and 262 (118 females, 144 males) were eligible. Vitamin C intake was derived from the Food Frequency Questionnaire (FFQ).
Thijs M. H. de Jong   +4 more
wiley   +1 more source

Improving nutritional assessment in pediatric anorexia nervosa: Clinical value of key serum biomarkers

open access: yesJournal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Reliable biochemical markers of starvation are needed to improve detection and monitoring of starvation in pediatric anorexia nervosa (AN), thus we explored new and revisited old potential serum biochemical markers. Methods In this prospective cohort study we included 65 pediatric patients with AN.
Ante Vidović   +8 more
wiley   +1 more source

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