Results 61 to 70 of about 232,178 (355)

Estrogenic/Progestin therapy and the development of Vestibular Schwannoma: A systematic review and meta-analysis

open access: yesBrazilian Journal of Otorhinolaryngology
Objective: Compare the risk of developing Vestibular schwannoma in patients prescribed Hormone Therapy (HT). Methods: We performed a systematic review in accordance with the Preferred Reporting Items for Systematic reviews and Meta-Analysis (PRISMA), the
Maria Vitória Graça Couto de Campos Amaral   +1 more
doaj   +1 more source

The menopause and hormone replacement therapy [PDF]

open access: yes, 2014
Hormone replacement therapy can ease the symptoms of the menopause. The National Institute of Health and Care Excellence (NICE) is developing guidelines on the diagnosis and management of menopause, which are due for release in October 2015.
Nuttall, Dilyse
core   +1 more source

Functional Integration of Different‐Sex Gonad Transplants Into the Adult Mouse Hypothalamic Pituitary Gonadal Axis

open access: yesAdvanced Biology, EarlyView.
This study introduces and investigates different‐sex gonad transplants in a mouse model of gender‐affirming hormone therapy. Ovaries and testes implanted into gonadectomized adults exhibit gametogenesis and steroidogenesis independent of the sex of the host.
Daniel R. Pfau   +8 more
wiley   +1 more source

The Controversial History of Hormone Replacement Therapy

open access: yesMedicina, 2019
The history of hormone replacement therapy (HRT) started in the 1960s, with very high popularity in the 1990s. The first clinical trials on HRT and chronic postmenopausal conditions were started in the USA in the late 1990s. After the announcement of the
Angelo Cagnacci, Martina Venier
doaj   +1 more source

WISDOM: history and early demise - was it inevitable?

open access: yes, 2007
In 1989, the UK Medical Research Council (MRC) agreed that, if feasible, a randomized controlled trial to assess the long-term risks and benefits of hormone replacement therapy (HRT) was a priority.
Darbyshire, J, Meade, T, Vickers, M
core   +1 more source

Primary Human Tissue Models for Metabolic Dysfunction‐Associated Liver Disease ‐ toward Streamlining Drug Discovery with Patient‐Derived Assays

open access: yesAdvanced Biology, EarlyView.
The review provides a critical up‐to‐date overview of the current landscape of human in vitro models for fatty liver disease, including spheroids, organoids, organ‐on‐a‐chip systems, bioprinted liver constructs and precision‐cut liver slices. Their utility for faithfully modeling different stages of MASLD and MASH are evaluated and their compatibility ...
Sonia Youhanna   +6 more
wiley   +1 more source

Hormone Replacement Therapy, Likely Neither Angel Nor Demon. [PDF]

open access: yesPLoS ONE, 2015
A decline in breast cancer incidence has been attributed to the reduction in hormone replacement therapy (HRT) prescriptions since the publication of the landmark WHIT paper in 2003.
Mitchell S Wachtel   +3 more
doaj   +1 more source

3D Bioprinting of Thick Adipose Tissues with Integrated Vascular Hierarchies

open access: yesAdvanced Functional Materials, Volume 35, Issue 12, March 18, 2025.
An advanced 3D bioprinting technique is used here to create thick adipose tissues with a central, vessel and extensive branching. The construct is made using alginate, gelatin and collagen‐based bioinks. Flow through the complex vessel network is demonstrated as well as its successful integration with a femoral artery following implantation in a rat ...
Idit Goldfracht   +5 more
wiley   +1 more source

Decreased risk of breast cancer associated with oral bisphosphonate therapy [PDF]

open access: yes, 2012
Preclinical studies and adjuvant trials using bisphosphonates have found them to have an antitumor effect. Although major advances have been made in chemoprevention strategies with selective estrogen receptor modulators and aromatase inhibitors, their ...
Brufsky, A, Mathew, A
core   +2 more sources

Hormone replacement therapy and the breast

open access: yesSurgical Oncology, 2001
Increasing numbers of women are using hormone replacement therapy (HRT) in their 50s and 60s. Oestrogen alone or oestrogen and progestogen combined given in this age group increase breast density and this has the effect of reducing both the sensitivity and specificity of breast screening in HRT users.
openaire   +4 more sources

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