Results 11 to 20 of about 6,835,633 (348)

Addition of docetaxel, zoledronic acid, or both to first-line long-term hormone therapy in prostate cancer (STAMPEDE): survival results from an adaptive, multiarm, multistage, platform randomised controlled trial

Lancet, The, 2016
Summary Background Long-term hormone therapy has been the standard of care for advanced prostate cancer since the 1940s. STAMPEDE is a randomised controlled trial using a multiarm, multistage platform design.
Nicholas D. James, Nicholas D. James, M. Sydes, N. Clarke, M. Mason, D. Dearnaley, M. Spears, A. Ritchie, C. Parker, J. Russell, G. Attard, J. Bono, W. Cross, Robert Jones, G. Thalmann, C. Amos, D. Matheson, R. Millman, M. Alzouebi, S. Beesley, A. Birtle, S. Brock, R. Cathomas, P. Chakraborti, S. Chowdhury, A. Cook, T. Elliott, J. Gale, S. Gibbs, J. Graham, J. Hetherington, R. Hughes, R. Laing, F. McKinna, D. McLaren, J. O’Sullivan, O. Parikh, C. Peedell, A. Protheroe, A. Robinson, N. Srihari, R. Srinivasan, J. Staffurth, S. Sundar, S. Tolan, D. Tsang, J. Wagstaff, M. Parmar   +47 more
semanticscholar   +3 more sources

Hormone Therapy, Mental Health, and Quality of Life Among Transgender People: A Systematic Review

Journal of the Endocrine Society, 2021
We sought to systematically review the effect of gender-affirming hormone therapy on psychological outcomes among transgender people. We searched PubMed, Embase, and PsycINFO through June 10, 2020 for studies evaluating quality of life (QOL), depression,
Kellan E. Baker, L. Wilson, Ritu Sharma, Vadim Dukhanin, K. McArthur, K. Robinson   +5 more
semanticscholar   +1 more source

Preoperative Hormone Therapy in the Treatment of Breast Cancer: What Do We Know So Far?

Креативная хирургия и онкология, 2022
Breast cancer is the most common malignant disease in the world. One of the methods of treating breast cancer is neoadjuvant chemotherapy. Neoadjuvant chemotherapy (NCT) is now the standard of care for locally advanced breast cancer.
V. V. Vorotnikov, R. A. Pakhomova, A. V. Soinov, A. S. Gunina, I. V. Kopytich, M. G. Tsoi, S. A. Abdugafforov   +6 more
doaj   +1 more source

Risks, Benefits, and Treatment Modalities of Menopausal Hormone Therapy: Current Concepts

Frontiers in Endocrinology, 2021
Menopausal hormone therapy (HT) prescribing practices have evolved over the last few decades guided by the changing understanding of the treatment’s risks and benefits.
Jaya M Mehta, J. Kling, J. Manson
semanticscholar   +1 more source

Menopausal hormone therapy and women’s health: An umbrella review

PLoS Medicine, 2021
Background There remains uncertainty about the impact of menopausal hormone therapy (MHT) on women’s health. A systematic, comprehensive assessment of the effects on multiple outcomes is lacking.
Guo-Qiang Zhang, Jin-Liang Chen, Ying Luo, Maya B. Mathur, P. Anagnostis, U. Nurmatov, M. Talibov, Jing Zhang, C. Hawrylowicz, M. Lumsden, H. Critchley, A. Sheikh, B. Lundbäck, Cecilia Lässer, Hannu Kankaanranta, S. H. Lee, B. Nwaru   +16 more
semanticscholar   +1 more source

Menopausal hormone therapy for the management of osteoporosis.

Best practice & research. Clinical endocrinology & metabolism, 2021
Postmenopausal osteoporosis is a frequent clinical condition which affects nearly 1 in 3 women. Estrogen deficiency leads to rapid bone loss which is maximal within the first 2-3 years after the menopause transition and can be prevented by menopause ...
A. Gosset, J. Pouillès, F. Trémollieres   +2 more
semanticscholar   +1 more source

A systematic review of psychosocial functioning changes after gender-affirming hormone therapy among transgender people

Nature Human Behaviour, 2022
This systematic review assessed the state and quality of evidence for effects of gender-affirming hormone therapy on psychosocial functioning. Forty-six relevant journal articles (six qualitative, 21 cross-sectional, 19 prospective cohort) were ...
D. Doyle, T. Lewis, M. Barreto
semanticscholar   +1 more source

Bioidentical Hormone Therapy [PDF]

Mayo Clinic Proceedings, 2011
The change in hormonal milieu associated with perimenopause and menopause can lead to a variety of symptoms that can affect a woman's quality of life. Postmenopausal hormone therapy (HT) is an effective, well-tolerated treatment for these symptoms. However, combined HT consisting of conjugated equine estrogen and medroxyprogesterone acetate has been ...
Julia A, Files, Marcia G, Ko, Sandhya, Pruthi   +2 more
openaire   +2 more sources

RETRACTED: Effect of Weekly Long-Acting Growth Hormone Replacement Therapy Compared to Daily Growth Hormone on Children With Short Stature: A Meta-Analysis

Frontiers in Endocrinology, 2021
BackgroundWe performed a meta-analysis to evaluate the efficacy and safety of weekly long-acting growth hormone replacement therapy compared to daily growth hormone in children with short stature.MethodsA systematic literature search up to April 2021 was
Liyan Ma, Liangyi Li, Wen Pan, Congfu Huang, Limei Liu, Xiaoxiao Zhang, Xiaoxiao Zhang   +6 more
doaj   +1 more source

Recommended Hormone Therapy in Menopause: Concepts, Controversies and Approach to Treatment.

Endocrine reviews, 2021
Hormone therapy (HT) is an effective treatment for menopausal symptoms, including vasomotor symptoms and genitourinary syndrome of menopause. Randomized trials also demonstrate positive effects on bone health, and age-stratified analyses indicate more ...
V. A. Flores, L. Pal, Joann E Manson
semanticscholar   +1 more source