Results 221 to 230 of about 5,954,376 (381)

Menopausal Hormone Therapy and Long-term All-Cause and Cause-Specific Mortality: The Women’s Health Initiative Randomized Trials

Journal of the American Medical Association (JAMA), 2017
J. Manson, A. Aragaki, J. Rossouw, G. Anderson, R. Prentice, A. LaCroix, R. Chlebowski, B. Howard, C. Thomson, K. Margolis, C. Lewis, M. Stefanick, R. Jackson, K. Johnson, L. Martin, S. Shumaker, M. Espeland, J. Wactawski‐Wende   +17 more
semanticscholar   +1 more source

Human Bone‐Derived Endothelial Cells Mediate Bone Regeneration via Distinct Expression of KIT Ligand

Advanced Science, EarlyView.
Bone‐specific endothelial cells (b‐ECs) uniquely express KITLG, which recruits c‐Kit+/CD34+ hematopoietic progenitors (HPCs) to the osteovascular niche, initiating a cascade that culminates in the osteogenic differentiation of bone marrow‐derived mesenchymal stem cells (bm‐MSCs) and subsequent ossification.
Xiang Li, Hwan D. Kim, Allen C. Luo, Liyan Gong, Yonglin Zhu, Chin Nien Lee, Xuechong Hong, Christopher L. Sudduth, Michal Ad, Young‐Hyeon An, Mihn Jeong Park, Do‐Gyoon Kim, Arin K. Greene, Bonnie L. Padwa, Nathaniel S. Hwang, Ruei‐Zeng Lin, Juan M. Melero‐Martin   +16 more
wiley   +1 more source

Climacteric women's perspectives on menopause and hormone therapy: Knowledge gaps, fears, and the role of healthcare advice. [PDF]

PLoS One
Rodrigues MAH, Reis ZSN, Verona APA, Teixeira MC, Pappa GL, Soares Junior JM, da Silva Filho AL, Baracat EC, Maciel GAR.   +8 more
europepmc   +1 more source

The Nuclear Localization of ACLY Guards Early Embryo Development Through Recruiting P300 and HAT1 to Promote Histone Acetylation and Transcription

Advanced Science, EarlyView.
ACLY is vital for early embryo development. IGF‐1 activates AKT to phosphorylate ACLY, driving its nuclear localization and recruitment of HATs (P300/HAT1), boosting acetyl‐CoA production and histone acetylation for transcriptional activation. Conversely, ACLY deficiency (via knockdown, knockout, or AKT inhibition) reduces nuclear acetyl‐CoA, disrupts ...
Yerong Ma, Yingyi Zhang, Weijie Yang, Xiaomei Tong, Siya Liu, Yan Zhou, Mengjia Qiu, Huifang Jiang, Zhanhong Hu, Peipei Ren, Yan Rong, Mengru Lai, Jiamin Jin, Fei Huang, Liujian Ouyang, Feng Zhou, Heng‐Yu Fan, Yin‐Li Zhang, Songying Zhang   +18 more
wiley   +1 more source

A longitudinal analysis on the effect of hormone use on allostatic load in perimenopausal women

Aging and Health Research
Background: Allostatic load (AL), a measure of physiologic dysregulation across multiple systems, has been shown to increase as women age and go through menopause. While hormone use has been shown to help with the relief of menopausal symptoms, it is not
Pamela Lamisi Alebna, Joaquin Ignacio Armendano, Nasim Maleki   +2 more
doaj  

FINAL STATURE AFTER GROWTH HORMONE (GH) THERAPY IN RADIATION-INDUCED GH DEFICIENCY [PDF]

, 1988
Peter Clayton, Stephen M. Shalet, David Price   +2 more
openalex   +1 more source

The Non‐Canonical ChREBPα Activity Suppresses the Activation of Hepatic Stellate Cells and Liver Fibrosis by Antagonizing TGF‐β‐E2F1 Axis

Advanced Science, EarlyView.
Intrahepatic microenvironment greatly impacts duration and degree of HSCs activation and development of liver fibrosis. By inhibiting TGFβ‐E2F1‐driven production of profibrogenic factors (CTGF and THBS1), hepatocyte ChREBPα monitors hepatic microenvironment and suppresses the overactivation of HSCs.
Jian Zhang, Yuee Zhao, Gauthami Pulivendala, Qing Zhang, Liangyou Rui, Jiashi Gao, Huiwen Wang, Gary Zhang, Alli Nuotio‐Antar, Xin Tong, Lei Yin   +10 more
wiley   +1 more source

Hormone Therapy and Cardiovascular Disease

Taiwanese Journal of Obstetrics & Gynecology, 2007
Horng-Jyh Tsai, MD, FACOG
doaj   +1 more source

Reply: Reassessing CAC Risk Post-RRSO: The Overlooked Role of Hormone Therapy. [PDF]

JACC CardioOncol
Beekman MJ, Terra L, Heemskerk-Gerritsen BAM, Hooning MJ, Maas AHEM, van Leeuwen FE.   +5 more
europepmc   +1 more source

Maintenance of Unimplanted Fertilized Ova in Sprayed Rats. IV. Effects of Duration of Ovarian Hormone Deprivation and Progesterone Therapy Prior to the Deprivation [PDF]

, 1987
R. L. Cochrane
openalex   +1 more source