Results 71 to 80 of about 56,064 (298)

A Blood‐Derived Factor Rescues ALS: Platelet Factor 4 Activates OPTN‐Dependent Autophagy to Clear SOD1 Aggregates Independently of PINK1

open access: yesAdvanced Science, EarlyView.
Systemic platelet factor 4 (PF4) is significantly depleted in amyotrophic lateral sclerosis (ALS). Peripheral PF4 replenishment restores central proteostasis by driving OPTN‐dependent, PINK1‐independent selective autophagy in motor neurons. This intervention effectively clears toxic SOD1 aggregates, blunts glial activation, and preserves neuromuscular ...
Qingjian Xie   +12 more
wiley   +1 more source

Substrate Engineering of SWCNT p–n Junctions for Dual‐Mode Power Generation and Heat‐Flux Sensing

open access: yesAdvanced Science, EarlyView.
Through substrate engineering alone, a single‐walled carbon nanotube p–n junction device switches between two functions under uniform infrared irradiation. A low‐absorbance substrate sustains a central hot junction for continuous power generation, whereas high‐absorbance substrates transiently invert the temperature gradient for sensitive heat‐flux ...
Ryota Tamai   +3 more
wiley   +1 more source

Preliminary estimation of optimal sample size for assessing the recruitment of Mesodesma donacium (Lamarck, 1818) on beaches of central-north Chile: Application of the power analysis

open access: yesCiencias Marinas, 2003
This work presents a preliminary study to estimate the optimal sample size for the assessment of recruitment of Mesodesma donacium, an important bivalve that supports an intensive fishery in the most important bays of northern Chile.
MA Ortiz, WB Stotz
doaj   +1 more source

Endothelial YAP Signaling Promotes Blood‐Spinal Cord Barrier Repair in Mice After Spinal Cord Injury

open access: yesAdvanced Science, EarlyView.
Endothelial YAP is required for blood‐spinal cord barrier repair after spinal cord injury. YAP‐dependent vascular repair is associated with ANGPT1/PI3K/AKT signaling in vivo and may involve endothelial‐pericyte paracrine interactions. By supporting vascular remodeling, tight junction restoration, restored pericyte coverage, and astrocyte‐vascular ...
Jiawei Wang   +14 more
wiley   +1 more source

Vol. 6: Horns

open access: yes, 1959
Stamps from around the world depicting horns and horn playing. Collectors sheet, Israel; Universal Postal Union, Sweden; Bugler, New Zealand; Post Horns, Switzerland (1959)

core   +1 more source

A SEBACEOUS HORN. [PDF]

open access: yesThe Lancet, 1917
n ...
openaire   +1 more source

Loss of SHP1 in Spinal Astrocytes Triggers T‐Lymphocyte Infiltration and Nociceptive Hypersensitivity

open access: yesAdvanced Science, EarlyView.
Astrocyte‐specific SHP1 deletion disrupts astrocyte–vascular interactions and compromises BBB integrity while enhancing STAT1‐dependent CXCL10 expression. These changes synergistically promote peripheral CD4+ and CD8+ T‐cell infiltration into the SDH. The infiltrating T cells secrete IFN‐γ, which in turn activates microglia.
Lan‐Xing Yi   +7 more
wiley   +1 more source

GROSS PATHOLOGICAL CHANGES IN UTERINE HORNS OF BUFFALOES SLAUGHTERED AT HYDERABAD ABATTOIR

open access: yesPakistan Veterinary Journal, 2001
Gross pathological changes in 1, Iterine horns of buffaloes slaughtered during 1994-95 in Hyderabad abattoir were studied. For this purpose, uterine horns of 100 female buffaloes of various age groups, including 35 heifers, 25 adults and 40 aged ...
W.M. Bhatti, M.S. Phulan, R. Rind and N. M. Soomro
doaj  

Shedding New Light on Cutaneous Horns: A Comprehensive Review and Pitfall of Management

open access: yesIndian Journal of Dermatology
A cutaneous horn, also known as cornu cutaneum, is an uncommon protuberance of highly compacted keratinous material from the stratum corneum, resembling an animal horn.
Leo Wan   +3 more
doaj   +1 more source

SemanticST: A Scalable Multi‐Contextual Graph Learning Framework for Uncovering Spatial Niches and Robust Multi‐Sample Integration in Spatial Transcriptomics

open access: yesAdvanced Science, EarlyView.
Technical limitations often let dominant signals overshadow rare cell types and fine‐grained heterogeneity in spatial transcriptomics. SemanticST, a graph neural network using multi‐semantic graph fusion and a novel min‐cut loss, recovers these subtle patterns.
Roxana Zahedi   +7 more
wiley   +1 more source

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