Results 41 to 50 of about 360,347 (313)

Microenvironmental Reprogramming by 3D Anisotropic Cardiac Extracellular Matrix Induces Nuclear Remodeling and Epigenetic Maturation of Chemically Induced Cardiomyocytes

open access: yesAdvanced Functional Materials, EarlyView.
A 3D anisotropic hydrogel derived from heart extracellular matrix guides cytoskeletal alignment and nuclear remodeling in reprogrammed cardiomyocyte‐like cells. This study reveals how matrix alignment modulates nuclear envelope dynamics and chromatin state, triggering transcriptional and functional maturation.
Seung Ju Seo   +7 more
wiley   +1 more source

Aggression, Erection, and Masturbation in Feral Pottoka Ponies and Implications for Equine Welfare

open access: yesAnimals, 2022
Erection and masturbation in horses are considered unwanted behaviors in training contexts, despite recognition that these are naturally occurring behaviors that are integral to the welfare of male horses.
Katherine Grillaert
doaj   +1 more source

Natural Biomaterials for Osteochondral Repair: From Source to Strategy

open access: yesAdvanced Healthcare Materials, EarlyView.
Biological origin‐guided overview of natural biomaterials and therapeutic strategies for osteochondral tissue engineering. The circular diagram categorizes representative materials and strategies into plant/algae‐derived, microbial‐derived, animal‐derived, and human‐derived sources, centered on an osteochondral defect repair model.
Hengyu Liu   +5 more
wiley   +1 more source

TBX3 and ASIP genotypes reveal discrepancies in officially recorded coat colors of Hucul horses

open access: yesAnimal, 2019
Although only a few specific pigmentation types are allowed within the Hucul horse registry, accurate determination of particular coat colors can be uncertain due to the presence of variation in color shades and segregation of multiple dun dilution ...
M. Mackowski   +3 more
doaj   +1 more source

Dexime: A Selectively Enzyme‐Degradable Hydrogel for Protein Therapeutic Release

open access: yesAdvanced Materials, EarlyView.
A dextrin‐oxime hydrogel (dexime) is produced using ketone or aldehyde modified dextrin and tetra‐oxyamine modified poly(ethylene glycol). The rheological and mechanical properties of dexime are tunable. Dexime is injectable, cytocompatible, hydrolytically stable, and selectively degradable by α‐amylase.
Quinton E. A. Sirianni   +5 more
wiley   +1 more source

Genetic diversity in Hucul and Polish primitive horse breeds [PDF]

open access: yesArchives Animal Breeding, 2015
Pedigree and molecular data were used to evaluate genetic diversity in the Polish populations of the Polish primitive horse (also known as Polish Konik) and Hucul breeds over the time period of 30 years (1980–2011).
M. Mackowski   +3 more
doaj   +1 more source

Mechanically Spatio‐Chimeric Fibrin Assembly Enables Vascular‐Integrated Muscle Reconstruction for Volumetric Muscle Loss Repair

open access: yesAdvanced Materials, EarlyView.
SPARC (spatio‐chimeric, plasma‐based, anisotropic, and shear‐responsive construct) that integrates myogenic and vascular microenvironments within a single construct. The dual‐modulus matrix directs aligned myotube formation and endothelial network development, enabling a vascularized muscle implant that seamlessly anastomoses with host tissue and ...
Su Hyun Jung   +6 more
wiley   +1 more source

Conductive Hydrogels for Exogenous Sensing and Cell Fate Control

open access: yesAdvanced Materials, EarlyView.
We engineer electrically conductive hydrogels by combining sulfated glycosaminoglycans with semiconducting polymers. These hydrogels bind bioactive proteins, including growth factors, whose release or retention can be modulated by low‐voltage stimulation. The hydrogels are also integrated as 3D channels in organic electrochemical transistors as part of
Teuku Fawzul Akbar   +15 more
wiley   +1 more source

The Frequency of Errors in Determining Age Based on Selected Features of the Incisors of Icelandic Horses

open access: yesAnimals, 2019
The structure and changes occurring to horses’ teeth during ontogeny are not only used to assess the degree of somatic maturity but also the development of universal patterns and is therefore used to determine the age of horses. Research shows that
Jarosław Łuszczyński   +3 more
doaj   +1 more source

Social Licence to Operate: What Can Equestrian Sports Learn from Other Industries?

open access: yesAnimals, 2022
The concept of ‘social licence to operate’ (SLO) is relevant to all animal-use activities. An SLO is an intangible, implicit agreement between the public and an industry/group.
Janet Douglas   +2 more
doaj   +1 more source

Home - About - Disclaimer - Privacy