Results 61 to 70 of about 1,352,103 (351)

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

open access: yesAging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey   +12 more
wiley   +1 more source

Aggression, Erection, and Masturbation in Feral Pottoka Ponies and Implications for Equine Welfare

open access: yesAnimals, 2022
Erection and masturbation in horses are considered unwanted behaviors in training contexts, despite recognition that these are naturally occurring behaviors that are integral to the welfare of male horses.
Katherine Grillaert
doaj   +1 more source

Microfluidic Platform for Multiparametric Profiling of Fibrin Permeability, Fibrinolysis, and Cell Invasion

open access: yesAdvanced Functional Materials, EarlyView.
This paper introduces a single‐channel H‐junction microfluidic assay that profiles fibrin's evolving function in repair and thrombosis by measuring, in one ∼3 µL gel, permeability, fibrinolysis kinetics, fibroblast invasion, and clot extension in real time.
Halston Deal   +9 more
wiley   +1 more source

Genetic diversity in Hucul and Polish primitive horse breeds [PDF]

open access: yesArchives Animal Breeding, 2015
Pedigree and molecular data were used to evaluate genetic diversity in the Polish populations of the Polish primitive horse (also known as Polish Konik) and Hucul breeds over the time period of 30 years (1980–2011).
M. Mackowski   +3 more
doaj   +1 more source

Microenvironmental Reprogramming by 3D Anisotropic Cardiac Extracellular Matrix Induces Nuclear Remodeling and Epigenetic Maturation of Chemically Induced Cardiomyocytes

open access: yesAdvanced Functional Materials, EarlyView.
A 3D anisotropic hydrogel derived from heart extracellular matrix guides cytoskeletal alignment and nuclear remodeling in reprogrammed cardiomyocyte‐like cells. This study reveals how matrix alignment modulates nuclear envelope dynamics and chromatin state, triggering transcriptional and functional maturation.
Seung Ju Seo   +7 more
wiley   +1 more source

Lysosome‐Acidifying Nanoparticles Rescue A30P α‐Synuclein Induced Neuronal Death in Cellular and Drosophila Models of Parkinson's Disease

open access: yesAdvanced Healthcare Materials, EarlyView.
Lysosome‐targeted acidic nanoparticles based on a biodegradable poly(ethylene tetrafluorosuccinate‐co‐succinate) copolymer are engineered to restore impaired lysosomal acidification through pH‐responsive intracellular degradation. Localized acid release enhances autophagic proteolysis, reduces α‐synuclein accumulation, and preserves dopaminergic neuron
Chih Hung Lo   +6 more
wiley   +1 more source

The Frequency of Errors in Determining Age Based on Selected Features of the Incisors of Icelandic Horses

open access: yesAnimals, 2019
The structure and changes occurring to horses’ teeth during ontogeny are not only used to assess the degree of somatic maturity but also the development of universal patterns and is therefore used to determine the age of horses. Research shows that
Jarosław Łuszczyński   +3 more
doaj   +1 more source

Social Licence to Operate: What Can Equestrian Sports Learn from Other Industries?

open access: yesAnimals, 2022
The concept of ‘social licence to operate’ (SLO) is relevant to all animal-use activities. An SLO is an intangible, implicit agreement between the public and an industry/group.
Janet Douglas   +2 more
doaj   +1 more source

From Grain to Feed [PDF]

open access: yes, 2010
Horse beans are used as an example of grain, which have potentials to substitute fish meal in fish feed. After several grinding and fractionation steps it was possible to obtain a protein-rich horse bean fraction with a yield of 19 %.
Hansen, Jonas H., Petersen, Hanne T.
core  

SiO2‐CaOCME/Poly(Tetrahydrofuran)/Poly(Caprolactone) 3D‐Printed Scaffolds Drive Human‐Bone Marrow Stromal Cell Osteogenic Differentiation

open access: yesAdvanced Healthcare Materials, EarlyView.
3D printed hybrid scaffolds combining bioactive silica–calcium chemistry with elastic polymers guide human bone stem cells to form bone. The scaffolds support cell survival, organization, and invasion while releasing osteogenic ions. Together, architecture and composition drive bone‐specific gene expression, extracellular matrix organization, and ...
David R. Sory   +3 more
wiley   +1 more source

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