Results 71 to 80 of about 517,121 (357)

Genome Sequence, Comparative Analysis, and Population Genetics of the Domestic Horse

Science, 2009
A Horse Is a Horse, of Course The history of horse domestication is closely tied to the history of the human society. Wade et al. (p. 865) report on the sequencing and provide a single nucleotide polymorphism map of the horse (Equus caballus) genome ...
C. Wade, E. Giulotto, S. Sigurdsson, Monica Zoli, S. Gnerre, F. Imsland, T. Lear, D. Adelson, E. Bailey, R. Bellone, H. Blöcker, O. Distl, Robert C. Edgar, Manuel Garber, T. Leeb, E. Mauceli, J. MacLeod, M. Penedo, J. Raison, Ted Sharpe, J. Vogel, L. Andersson, D. Antczak, T. Biagi, M. Binns, B. Chowdhary, S. J. Coleman, G. Valle, Sarah Fryc, G. Guérin, T. Hasegawa, E. Hill, J. Jurka, A. Kiialainen, G. Lindgren, Jinze Liu, E. Magnani, J. Mickelson, J. Murray, S. Nergadze, R. Onofrio, S. Pedroni, M. Piras, T. Raudsepp, M. Rocchi, K. Røed, O. Ryder, S. Searle, L. Skow, J. Swinburne, A. Syvänen, T. Tozaki, S. Valberg, M. Vaudin, J. White, M. Zody, E. Lander, K. Lindblad-Toh   +57 more
semanticscholar   +1 more source

Germanane Quantum Dots Promote Metabolic Reprogramming of Immune Cells Toward Regulatory T Cells and Suppress Inflammation In Vitro and In Vivo

Advanced Functional Materials, EarlyView.
Metabolic changes in immune cells direct the phenotype and function of the host immune system. Smart nanomaterials must target metabolic pathways to direct immune cell fate. This study reports the fabrication and first application of germanane quantum dots (GeHQDs) to modulate inflammation in vitro and in vivo.
Abhay Srivastava, Alireza Rafieerad, Weiang Yan, Keshav Narayan Alagarsamy, Qingdong Guan, Leena Regi Saleth, Michel Aliani, Sanjiv Dhingra   +7 more
wiley   +1 more source

Horse Pancreatic Ribonuclease [PDF]

European Journal of Biochemistry, 1974
Horse ribonuclease was purified after acid extraction of pancreas by ammonium sulfate fractionation and chromatography on CM‐cellulose. It is a glycoprotein with an average molecular weight of about 18000. The pure enzyme was chromatographically and electrophoretically heterogeneous due to the heterogeneity of the carbohydrate moiety.The amino‐acid ...
SCHEFFER, AJ, BEINTEMA, JJ
openaire   +3 more sources

RNA‐Micelles as Self‐Assembling Structures for Efficient Co‐Delivery of Synergistic siRNA and Nucleoside Analogues to Treat CRC Lung Metastasis

Advanced Functional Materials, EarlyView.
Two kinds of self‐assembled RNA micelles were used to co‐deliver synergistic siRNA and nucleoside analogues for the treatment of colorectal cancer lung metastases. Near‐complete elimination of lung cancer metastases was confirmed in an orthotopic lung metastasis model constructed using human colorectal cancer lung metastases patient surgical samples to
Kai Jin, Piotr Rychahou, Daniel W. Binzel, B. Mark Evers, Peixuan Guo   +4 more
wiley   +1 more source

Features of the free radical status of the follicular fluid of mares in the process of folliculogenesis

Siberian Journal of Life Sciences and Agriculture
Background.  The maturation of germ cells is a complex and multilevel process. To increase the effectiveness of assisted reproductive technologies in horses, a detailed study of the mechanisms of regulation of folliculogenesis is necessary. Purpose. A
Valery V. Kalashnikov, Lyudmila F. Lebedeva, Olga V. Bakovetskaya, Anna A. Terekhina, Elena V. Solodova, Yulia V. Abalenikhina, Aleksey V. Shchulkin   +6 more
doaj   +1 more source

Astrocyte‐Guided Maturation of Neural Constructs in a Modular Biosynthetic Hydrogel for Biohybrid Neurotechnologies

Advanced Functional Materials, EarlyView.
A modular biosynthetic PVA–gelatin hydrogel crosslinked via visible‐light thiol‐ene chemistry is engineered as a coating for neural electrodes. Optimizing matrix composition and mechanical properties enables the hydrogel to support astrocytic populations that guide neural differentiation and functional maturation.
Martina Genta, Sofia Peressotti, Roberto Portillo‐Lara, Josef Goding, Rylie Green   +4 more
wiley   +1 more source

Horsing Around—A Dataset Comprising Horse Movement [PDF]

Data, 2019
Movement data were collected at a riding stable over seven days. The dataset comprises data from 18 individual horses and ponies with 1.2 million 2-s data samples, of which 93,303 samples have been tagged with labels (labeled data). Data from 11 subjects were labeled. The data from six subjects and six activities were labeled more extensively.
Jacob W. Kamminga, Lara M. Janßen, Nirvana Meratnia, Paul J. M. Havinga   +3 more
openaire   +2 more sources

A Critical Review of Horse-Related Risk: A Research Agenda for Safer Mounts, Riders and Equestrian Cultures

Animals, 2015
While the importance of improving horse-related safety seems self-evident, no comprehensive study into understanding or reducing horse-related risk has been undertaken. In this paper, we discuss four dimensions of horse-related risk: the risk itself, the
K. Thompson, P. McGreevy, P. McManus
semanticscholar   +1 more source

Geometrically Tunable Scaffold‐Free Muscle Bioconstructs for Treating Volumetric Muscle Loss

Advanced Healthcare Materials, EarlyView.
Volumetric muscle loss is associated with traumatic muscle resulting in permanent functional impairment. Mold‐based, scaffold‐free, high‐density muscle tissue bioconstructs are developed in customizable geometric shapes and sizes. The transplanted rectangular solid‐shaped muscle bioconstructs improved muscle force recovery and tissue regeneration in ...
Bugra Ayan, Gaoxian Chen, Ishita Jain, Sha Chen, Gladys Chiang, Caroline Hu, Renato Reyes, Beu P. Oropeza, Ngan F. Huang   +8 more
wiley   +1 more source

Metallofullerenol Sc3N@C80(OH)18: A New Generation Radioprotector Protecting Human Erythrocytes Against Multiple Biochemical Damage Modes Upon Gamma Irradiation, Identifying It as a Scavenger of Short‐ and Long‐Lived Radicals

Advanced Healthcare Materials, EarlyView.
Metallofullerenol Sc3N@C80(OH)18 demonstrates strong radioprotective properties as a scavenger of both short‐ and long‐lived radicals. The study reveals protection of human erythrocytes from γ‐radiation–induced biochemical damage via post‐irradiation removal of primary and secondary reactive oxidants, supported by pulse radiolysis kinetics.
Jacek Grebowski, Maciej Studzian, Szymon Lekki‐Porebski, Anna Konarska, Marian Wolszczak, Grzegorz Litwinienko, Lukasz Pulaski   +6 more
wiley   +1 more source