Results 91 to 100 of about 313,588 (356)
Regulation of Neuroinflammation by Microglial DUBA‐IRAK1‐IKKβ Signaling Loop
Advanced Science, EarlyView.The protein levels of deubiquitinating enzyme A (DUBA) are rapidly upregulated in microglia after activation of Toll‐like receptor 4 (TLR4). In turn, DUBA potentiates TLR4‐induced proinflammatory signal transduction in microglia by stabilizing interleukin‐1 receptor activated kinase 1 (IRAK1) through K48 deubiquitination.
Zhenhu Zhu +22 more
wiley +1 more source
, 2008 The multidrug-resistant (MDR) Salmonella enterica serotype Newport strain that produces CMY-2 β-lactamase(Newport MDR-AmpC) was the source of sporadic cases and outbreaks in humans in France during 2000–2005.
Achtman, M. +13 more
core +1 more source
EHV-1 Pathogenesis: Current in vitro Models and Future Perspectives [PDF]
, 2019 Primary infection and pathogenesis of equine herpesvirus type 1 (EHV-1) require an intricate interaction of virus with the mucosal epithelium, mononuclear cells and the vascular endothelium.
Azab, Walid +3 more
core +1 more source
Advanced Science, EarlyView.Psychological stress activates the sympathetic–adrenal axis, elevating norepinephrine (NE) and suppressing reproductive hormones, thereby impairing male reproduction. Excess NE overactivates and desensitizes β‐adrenergic receptors (β‐ARs), triggering Sertoli cell ferroptosis and disrupting spermatogenesis.
Lingyu Zhang +12 more
wiley +1 more source
Health Problems and Risk Factors Associated with Long Haul Transport of Horses in Australia
Animals, 2015 Equine transportation is associated with a variety of serious health disorders causing economic losses. However; statistics on horse transport are limited and epidemiological data on transport related diseases are available only for horses transported to
Barbara Padalino +6 more
doaj +1 more source
One‐Step Drug Screening System Utilizing Electrophysiological Activity in Multiple Brain Organoids
Advanced Science, EarlyView.This study presents a one‐step system that delivers different drug doses to brain organoids and monitors their neural activity using integrated 3D microelectrodes. By combining dose‐specific microfluidic delivery with high‐resolution electrophysiological recording, the platform enables simultaneous, real‐time screening of neural responses across ...
Hyogeun Shin +9 more
wiley +1 more source
Contree, 2017 African Horse Sickness (AHS) is a devastating, non-contagious, infectious, insect-borne disease of equids. AHS is endemic to sub-Saharan Africa. Culicoides midges (Diptera: Ceratopogonidae) act as vectors for the transmission of the causative agent ...
Danica Liebenberg +3 more
doaj +1 more source
Characteristic of Individual Indicators of Endogenous Intoxication in the Experimental Asthma Dynamics and Their Correction by Thiotriasolin [PDF]
, 2016 The aim of this work was to find out the specifics of changes in endogenous intoxication, middle mass molecules (MMM) and erythrocyte intoxication index (EII) in the blood of animals for experimental asthma in different periods of its development and to ...
Kolishetska, M. (Marta)
core +2 more sources
Advanced Science, EarlyView.A novel modified SIRT6 variant (dSIRT6) H133Y‐mediated enrichment technique unmasks 15 new human lysine‐myristoylated proteins. Notably, Sirtuin 6 (SIRT6) demyristoylation of activating transcription factor 2 (ATF2) at K296 orchestrates its nucleoplasmic translocation.
Runyang Feng +40 more
wiley +1 more source