Bayesian Mendelian randomization methods for index trait bias correction in subsequent trait genome-wide association studies. [PDF]
Adhikari N +3 more
europepmc +1 more source
Humans are not unique: difficult birth is common in placental mammals
ABSTRACT Human childbirth is widely presumed to be uniquely difficult and dangerous compared to birth in other mammals. Tight fetopelvic proportions can result in obstructed labour and contribute to high rates of maternal and neonatal mortality. Ideas summarised under the ‘obstetrical dilemma’ have contributed to this assumption by explaining difficult
Nicole D. S. Grunstra
wiley +1 more source
Thyroid Disease in Horses-Retrospective Case Series on Patients Examined for Thyroid Disease in an Equine University Clinic (2009-2024). [PDF]
Stoeckle SD, Stage HJ, Gehlen H.
europepmc +1 more source
Ahmed I and "tuhfetü'l-mülûk ve's-selâtin": a period manuscript on horses, horsemanship and hunting [PDF]
Artan, Tulay, Artan, Tülay
core
ABSTRACT Background Chronic thromboembolic pulmonary disease (CTEPD) leads to chronic total occlusions (CTOs) of the pulmonary arteries in a minority of patients. Treatment of CTOs with balloon pulmonary angioplasty (BPA) may substantially improve patient hemodynamics but presents unique technical challenges and has previously been associated with a ...
Elliot J. Stein +4 more
wiley +1 more source
ABSTRACT Fluorouracil‐platinum(IV) prodrugs represent a novel class of multimechanistic chemotherapeutics with enhanced anticancer potential. The prodrugs PtIVP‐5FUMeOBut and PtIV56‐5FUMeOBut were actualized by derivatising the clinical drug 5‐fluorouracil (5FU) and coordinating it to platinum(IV) complexes, leveraging the established cytotoxicity of ...
Maria George Elias +9 more
wiley +1 more source
A multidisciplinary approach to the detection of and response to West Nile virus in the Netherlands between 2020 and 2023: best practices, challenges and opportunities. [PDF]
de Best PA +8 more
europepmc +1 more source
This work introduces the concept of pseudoglucosinolates (psGSLs) and reports the synthesis and evaluation of nitroreductase‐responsive psGSLs. These compounds represent a complementary prodrug strategy to natural glucosinolates (GSLs) for the controlled release of isothiocyanates (ITCs), enabling bio‐responsive protein labeling, as demonstrated in ...
Claire C. Jimidar +13 more
wiley +1 more source
Serial postoperative peritoneal fluid analyses in horses with naturally-occurring strangulating and non-strangulating gastrointestinal lesions. [PDF]
Granello ME +4 more
europepmc +1 more source

