Equine Asthma: Current Understanding and Future Directions [PDF]
Frontiers in Veterinary Science, 2020 The 2019 Havemeyer Workshop brought together researchers and clinicians to discuss the latest information on Equine Asthma and provide future research directions. Current clinical and molecular asthma phenotypes and endotypes in humans were discussed and
Laurent Couetil +14 more
doaj +13 more sources
The Most Common Environmental Risk Factors for Equine Asthma—A Narrative Review [PDF]
AnimalsEquine asthma is a popular subject of research. Many factors influencing the methods used to improve the welfare of asthmatic horses remain unclear. This study reviews scientific articles published after 2000 to collect the most important information on ...
Dorota Witkowska
exaly +5 more sources
Gene Expression Profiles of the Immuno-Transcriptome in Equine Asthma [PDF]
Animals, 2022 Background: Mild equine asthma (MEA) and severe equine asthma (SEA) are two of the most frequent equine airway inflammatory diseases, but knowledge about their pathogenesis is limited. The goal of this study was to investigate gene expression differences
Elisa Padoan +5 more
doaj +5 more sources
Initial Investigation of Molecular Phenotypes of Airway Mast Cells and Cytokine Profiles in Equine Asthma [PDF]
Frontiers in Veterinary Science, 2023 Equine asthma is a naturally occurring lung disease characterized by chronic, partially reversible airway obstruction, pulmonary remodeling, and lower airway inflammation.
Elizabeth Lennon +2 more
exaly +4 more sources
The Immune Mechanisms of Severe Equine Asthma—Current Understanding and What Is Missing [PDF]
Animals, 2022 Severe equine asthma is a chronic respiratory disease of adult horses, occurring when genetically susceptible individuals are exposed to environmental aeroallergens.
Paula Tilley, Joana Simões
exaly +4 more sources
Neuroimmune Mechanisms in Equine Asthma: Primary Inflammatory Triggers, Neuroimmune Modulation and Chronic Airway Remodelling [PDF]
AnimalsEquine asthma is a chronic inflammatory disease of the lower respiratory tract, primarily associated with inhalation of organic dust, microbial particles and environmental aeroantigens.
Małgorzata Wierzbicka +2 more
doaj +2 more sources
Inhalative Nanoparticulate CpG Immunotherapy in Severe Equine Asthma: An Innovative Therapeutic Concept and Potential Animal Model for Human Asthma Treatment [PDF]
Animals, 2022 Severe equine asthma is the most common globally widespread non-infectious equine respiratory disease (together with its mild and moderate form), which is associated with exposure to hay dust and mold spores, has certain similarities to human asthma, and
John Klier +3 more
doaj +2 more sources
Differences in Redox Biomarkers in Bronchoalveolar Lavage Fluid of Leisure Horses With and Without Severe Equine Asthma: Preliminary Results [PDF]
AnimalsEquine asthma is a common chronic respiratory disease characterized by airway inflammation and oxidative imbalance, particularly in its severe form.
Francesca Bindi +8 more
doaj +2 more sources
Investigation of nasal epithelial cells as a surrogate for bronchial epithelial cells in the research of equine asthma. [PDF]
PLoS ONE, 2023 Equine asthma, previously known as Recurrent Airway Obstruction (RAO) or Inflammatory Airway Disease (IAD), is an often-debilitating condition that may severely affect both performance and quality of life.
Diane Frances Lee +3 more
doaj +2 more sources
Airway Hyperresponsiveness, but Not Bronchoalveolar Inflammatory Cytokines Profiles, Is Modified at the Subclinical Onset of Severe Equine Asthma [PDF]
Animals, 2023 Airway hyperresponsiveness (AHR) and inflammation are both observed in human and equine asthma. The aim of this study was to assess the timeline and relationship of both features at the subclinical onset of severe equine asthma (SEA).
Thibault Frippiat +2 more
doaj +2 more sources