Results 41 to 50 of about 410,463 (191)

Omalizumab: clinical use for the management of asthma [PDF]

, 2012
Omalizumab, a humanized monoclonal antibody that binds circulating IgE antibody, is a treatment option for patients with moderate to severe allergic asthma whose asthma is poorly controlled with inhaled corticosteroids and inhaled long-acting ß2 agonist ...
Rekha Chaudhuri, Neil C. Thomson, Thomson, N.C., Chaudhuri, R.   +3 more
core   +1 more source

Clinical effect of corticosteroids in asthma-affected horses: A quantitative synthesis [PDF]

, 2018
There are limited findings from low-powered studies based on few number of subjects with equine asthma. Furthermore, no studies have been performed to assess a meaningful clinically detectable impact of corticosteroids in equine ...
P. Roncada, Calzetta, L, Rogliani, P., Calzetta L, P. Rogliani, M.G. Matera, C. Page, Roncada P, Urbani, A, Page, C, Matera, M G, Matera, Mg, C. Piras, Urbani A, Page C, Piras, C., Soggiu A, Piras C, Roncada, P, Matera MG, Matera, M. G., Soggiu, A., Piras, C, L. Calzetta, Urbani, A., Rogliani P, Pistocchini, E., Page, C., Pistocchini, E, Soggiu, A, Rogliani, P, A. Urbani, E. Pistocchini, A. Soggiu, Pistocchini E, Calzetta, L., Roncada, P.   +36 more
core   +1 more source

Metalloproteinases and their Inhibitors under the Course of Immunostimulation by CPG-ODN and Specific Antigen Inhalation in Equine Asthma

Mediators of Inflammation, 2019
Objectives. Inhalation of immunostimulatory bacterial DNA segments (cytosine-phosphate-guanosine-oligodeoxynucleotides, CpG-ODN) normalizes clinical and cytologic parameters in severe equine asthma.
Ann Kristin Barton, Tarek Shety, John Klier, Sabine Geis, Ralf Einspanier, Heidrun Gehlen   +5 more
doaj   +1 more source

Lung Function Variation during the Estrus Cycle of Mares Affected by Severe Asthma

Animals, 2022
While the prevalence of asthma is higher in boys than in girls during childhood, this tendency reverses at puberty, suggesting an effect of sex hormones on the disease pathophysiology.
Sophie Mainguy-Seers, Mouhamadou Diaw, Jean-Pierre Lavoie   +2 more
doaj   +1 more source

Equine Asthma in a Comparative Perspective: Cardiovascular and Neurological Manifestations of Asthma Across Different Species. [PDF]

Animals (Basel)
Asthma is a multifactorial respiratory disease that naturally occurs in horses, humans, and cats, presenting common clinical signs and species-specific mechanisms. This review addresses the impact of asthma on the cardiovascular and neurological systems, with a primary focus on horses.
Dlugopolska D, Siwinska N, Noszczyk-Nowak A.   +2 more
europepmc   +5 more sources

Impaired response of the bronchial epithelium to inflammation characterizes severe equine asthma

BMC Genomics, 2017
Background Severe equine asthma is a naturally occurring lung inflammatory disease of mature animals characterized by neutrophilic inflammation, bronchoconstriction, mucus hypersecretion and airway remodeling. Exacerbations are triggered by inhalation of
Laurence Tessier, Olivier Côté, Mary Ellen Clark, Laurent Viel, Andrés Diaz-Méndez, Simon Anders, Dorothee Bienzle   +6 more
doaj   +1 more source

Equine Asthma new definitions, diagnosis and management / Tumor markers in equine medicine / Computer-assisted surgery for horses – Potential clinical applications from "head to toe"?

, 2022
Gerber Vinzenz: Equine Asthma new definitions, diagnosis and management Unger Lucia: Tumor markers in equine medicine Koch Christoph: Computer-assisted surgery for horses – Potential clinical applications from "head to toe"
Unger, Lucia, Koch, Christoph, Gerber, Vinzenz   +2 more
core   +1 more source

Inadequate specialist care referrals for high risk asthma patients in the UK: an adult population-based cohort 2006-2017 [PDF]

, 2019
Objective: To improve asthma morbidity and mortality in the UK, national asthma guidelines recommend referral to specialist care for the following high risk groups, after a hospital admission for asthma, ≥3 courses of oral corticosteroids (OCS) in 12 ...
walker, samantha, Bloom, ci, Quint, jk
core   +1 more source

Heart rate variability in horses with and without severe equine asthma. [PDF]

Equine Vet J
Abstract Background Equine asthma in severe form (severe equine asthma [sEA]) shares remarkable similarities with human asthma. Human studies detected changes in the autonomic nervous system function in asthmatic patients based on heart rate variability (HRV) analysis.
Nyerges-Bohák Z, Kovács L, Povázsai Á, Hamar E, Póti P, Ladányi M.   +5 more
europepmc   +3 more sources

A comparison of nanoparticulate CpG immunotherapy with and without allergens in spontaneously equine asthma‐affected horses, an animal model

Immunity, Inflammation and Disease, 2018
Introduction New therapeutic strategies to modulate the immune response of human and equine allergic asthma are still under extensive investigation. Immunomodulating agents stimulating T‐regulatory cells offer new treatment options beyond conventional ...
John Klier, Sabine Geis, Jeanette Steuer, Katharina Geh, Sven Reese, Sebastian Fuchs, Ralf S. Mueller, Gerhard Winter, Heidrun Gehlen   +8 more
doaj   +1 more source