Alveolar macrophage phenotypes in severe equine asthma. [PDF]
Vet J, 2020 Because the alveolar macrophage (AM) phenotype of horses with severe equine asthma (SEA) is unknown, the cytokines expressed by M1- and M2-polarized AM were determined and the hypothesis that natural hay/straw challenge (NC) induces divergent AM phenotypes in control horses and horses with SEA was tested.
Wilson ME +3 more
europepmc +4 more sources
The Role of Thoracic Ultrasonography and Airway Endoscopy in the Diagnosis of Equine Asthma and Exercise-Induced Pulmonary Hemorrhage [PDF]
Veterinary Sciences, 2021 Chiara Maria Lo Feudo +2 more
exaly +2 more sources
An Integrative miRNA-mRNA Expression Analysis Reveals Striking Transcriptomic Similarities between Severe Equine Asthma and Specific Asthma Endotypes in Humans. [PDF]
, 2020 Severe equine asthma is an incurable obstructive respiratory condition affecting 10-15% of horses in temperate climates. Upon exposure to airborne antigens from hay feeding, affected horses show neutrophilic airway inflammation and bronchoconstriction ...
Jean-Pierre Lavoie +13 more
core +1 more source
Bronchoalveolar Lavage Cytology in Severe Equine Asthma: Cytocentrifugated versus Sediment Smear Preparations. [PDF]
Vet Sci, 2023 Equine asthma is a common respiratory disease that may affect horses of any age. The diagnosis of severe equine asthma (SEA) (historically referred as recurrent airway obstruction or RAO) is based mainly on the history of the animal and clinical signs ...
Morini M +7 more
europepmc +3 more sources
Equine asthma in Brazil – a scoping review
Research, Society and Development, 2022 Asthma is a chronic respiratory disease that can occur in horses of different breeds and ages. While its occurrence has been reported in many countries, its occurrence across Brazil is unclear. This review aimed to gather information about equine asthma from studies performed in Brazil by different groups and investigate a variety of horse populations.
Tiago Marcelo Oliveira +3 more
openaire +2 more sources
Efficacy of tamoxifen for the treatment of severe equine asthma [PDF]
Journal of Veterinary Internal Medicine, 2018 Abstract Background Tamoxifen, a selective estrogen receptor modulator, decreased airway neutrophilia and improved clinical signs in an experimental model of equine asthma, and induced neutrophilic apoptosis in vitro.
Sophie Mainguy-Seers +2 more
openaire +2 more sources
Neutrophil gelatinase‐associated lipocalin as a potential biomarker for equine asthma [PDF]
Equine Veterinary Journal, 2023 Abstract Background Studies in people have found neutrophil gelatinase‐associated lipocalin (NGAL) concentrations are increased in asthma and can be used to distinguish between asthma subtypes. NGAL has not yet been investigated in equine asthma (EA).
Sanni Hansen +4 more
openaire +3 more sources
BMC Veterinary Research, 2019 Background Mild equine asthma is a common inflammatory airway disease of the horse. The primary treatment of mild equine asthma is corticosteroids. The purpose of this study was to investigate the effects of injected dexamethasone on relative IL-1β, IL-4,
Stephanie L. Bond +2 more
doaj +1 more source
Leukotriene B4 in equine asthma syndrome: what do we know so far? [PDF]
Pesquisa Veterinária Brasileira, 2019 : The term “equine asthma syndrome” (EAS) was recently proposed due to the resemblance of the equine disease to human asthma. Leukotrienes cause constriction of the bronchi, especially in the lower airways and increase mucus secretion in the respiratory ...
Juliana N.P. Otaka +6 more
doaj +1 more source
Equine Asthma in a Comparative Perspective: Cardiovascular and Neurological Manifestations of Asthma Across Different Species. [PDF]
Animals (Basel)Asthma is a multifactorial respiratory disease that naturally occurs in horses, humans, and cats, presenting common clinical signs and species-specific mechanisms. This review addresses the impact of asthma on the cardiovascular and neurological systems, with a primary focus on horses.
Dlugopolska D +2 more
europepmc +5 more sources