The Immune Mechanisms of Severe Equine Asthma—Current Understanding and What Is Missing [PDF]
Severe equine asthma is a chronic respiratory disease of adult horses, occurring when genetically susceptible individuals are exposed to environmental aeroallergens.
Joana Simões +2 more
doaj +4 more sources
Airway Hyperresponsiveness, but Not Bronchoalveolar Inflammatory Cytokines Profiles, Is Modified at the Subclinical Onset of Severe Equine Asthma [PDF]
Airway hyperresponsiveness (AHR) and inflammation are both observed in human and equine asthma. The aim of this study was to assess the timeline and relationship of both features at the subclinical onset of severe equine asthma (SEA).
Thibault Frippiat +2 more
doaj +4 more sources
Decision Making in Severe Equine Asthma—Diagnosis and Monitoring [PDF]
Decision making consists of gathering quality data in order to correctly assess a situation and determine the best course of action. This process is a fundamental part of medicine and is what enables practitioners to accurately diagnose diseases and ...
Joana Simões, Paula Tilley
doaj +4 more sources
Immunohistochemical Expression of Neurokinin-A and Interleukin-8 in the Bronchial Epithelium of Horses with Severe Equine Asthma Syndrome during Asymptomatic, Exacerbation, and Remission Phase [PDF]
Severe equine asthma (EA) syndrome is a chronic obstructive disease characterized by exaggerated contraction, inflammation, and structural alteration of the airways in adult horses, when exposed to airborne molds and particulate material. However, little
Maria Morini +6 more
doaj +4 more sources
Intradermal Testing Results in Horses Affected by Mild-Moderate and Severe Equine Asthma [PDF]
Equine asthma is an inflammatory respiratory disorder, classified as mild-moderate (MEA) and severe (SEA). SEA is characterized by recurrent exacerbations, consisting of dyspnea, coughing and exercise intolerance; MEA causes poor performance, occasional ...
Chiara Maria Lo Feudo +5 more
doaj +4 more sources
The Dynamics of Circulating Immune Complexes in Horses with Severe Equine Asthma [PDF]
Non-invasive diagnostic biomarkers of equine asthma syndrome (EAS) from blood or urine are sought. The aim of this study was to assess the absorbance of circulating immune complexes (CICs) during the exacerbation, remission, and treatment of an asthma ...
Malwina Slowikowska +4 more
doaj +4 more sources
Co-Occurrence of Severe Equine Asthma and Palatal Disorders in Privately Owned Pleasure Horses [PDF]
According to the “unified or united airway disease” theory, diseases in the upper and lower airways frequently co-occur because they represent a single morphological and functional unit. Palatal disorders (PDs) and severe equine asthma (SEA) are frequent
Natalia Kozłowska +3 more
doaj +4 more sources
Inhalative Nanoparticulate CpG Immunotherapy in Severe Equine Asthma: An Innovative Therapeutic Concept and Potential Animal Model for Human Asthma Treatment [PDF]
Severe equine asthma is the most common globally widespread non-infectious equine respiratory disease (together with its mild and moderate form), which is associated with exposure to hay dust and mold spores, has certain similarities to human asthma, and
John Klier +3 more
doaj +2 more sources
Bronchoalveolar Lavage Cytology in Severe Equine Asthma: Cytocentrifugated versus Sediment Smear Preparations [PDF]
Equine asthma is a common respiratory disease that may affect horses of any age. The diagnosis of severe equine asthma (SEA) (historically referred as recurrent airway obstruction or RAO) is based mainly on the history of the animal and clinical signs ...
Maria Morini +7 more
doaj +2 more sources
Differences in Redox Biomarkers in Bronchoalveolar Lavage Fluid of Leisure Horses With and Without Severe Equine Asthma: Preliminary Results [PDF]
Equine asthma is a common chronic respiratory disease characterized by airway inflammation and oxidative imbalance, particularly in its severe form.
Francesca Bindi +8 more
doaj +2 more sources

