Results 41 to 50 of about 1,927,081 (168)

Giant Multinucleated Cells Are Associated with Mastocytic Inflammatory Signature Equine Asthma

Animals, 2022
Equine asthma is currently diagnosed by the presence of increased neutrophil (>5%), mast cell (>2%), and/or eosinophil (>1%) differential cell count. Macrophages are normal resident cells within the alveoli.
Ilaria Basano, Alessandra Romolo, Giulia Iamone, Giulia Memoli, Barbara Riccio, Jean-Pierre Lavoie, Barbara Miniscalco, Michela Bullone   +7 more
doaj   +1 more source

Omalizumab: clinical use for the management of asthma [PDF]

, 2012
Omalizumab, a humanized monoclonal antibody that binds circulating IgE antibody, is a treatment option for patients with moderate to severe allergic asthma whose asthma is poorly controlled with inhaled corticosteroids and inhaled long-acting ß2 agonist ...
Rekha Chaudhuri, Neil C. Thomson, Thomson, N.C., Chaudhuri, R.   +3 more
core   +1 more source

Severely Asthmatic Horses Residing in a Mediterranean Climate Shed a Significantly Lower Number of Parasite Eggs Compared to Healthy Farm Mates

Animals, 2023
The relationship between helminth infection and allergic diseases has long intrigued the scientific community. This interaction was previously studied in a horse family with high incidence of severe equine asthma and in non-related severely asthmatic ...
Joana Simões, José Paulo Sales Luís, Luís Madeira de Carvalho, Paula Tilley   +3 more
doaj   +1 more source

Problematic severe asthma in children, not one problem but many: a GA(2)LEN initiative

, 2010
Although most children with asthma are easy to treat with low doses of safe medications, many remain symptomatic despite every therapeutic effort.
Hedlin G, Lødrup Carlsen K, PERONI, Diego, Problematic Severe Asthma in Childhood Initiative group, Bush A   +4 more
core   +2 more sources

Lung Function Variation during the Estrus Cycle of Mares Affected by Severe Asthma

Animals, 2022
While the prevalence of asthma is higher in boys than in girls during childhood, this tendency reverses at puberty, suggesting an effect of sex hormones on the disease pathophysiology.
Sophie Mainguy-Seers, Mouhamadou Diaw, Jean-Pierre Lavoie   +2 more
doaj   +1 more source

CHI3L1 polymorphisms, cord blood YKL-40 levels and later asthma development [PDF]

, 2016
Single nucleotide polymorphisms (SNPs) in chitinase 3-like 1 (CHI3L1), the gene encoding YKL-40, and increased serum YKL-40 levels are associated with severe forms of asthma. It has never been addressed whether SNPs in CHI3L1 and cord blood YKL-40 levels
Gorlanova, Olga, Olga Gorlanova, Latzin, Philipp, Frey, Urs, Jakob Usemann, Urs Frey, Philipp Latzin, Dominik Hartl, Mack, Ines, Hartl, Dominik, Schmidt, Anne, Röösli, Martin, Ines Mack, Usemann, Jakob, Martin Röösli, Anne Schmidt   +15 more
core   +2 more sources

EGF-induced bronchial epithelial cells drive neutrophil chemotactic and anti-apoptotic activity in asthma [PDF]

, 2013
Chronic damage and repair of the bronchial epithelium are features of asthma. We have previously reported that ex vivo stimulation of normal bronchial epithelial cells with epidermal growth factor (EGF), a key factor of epithelial repair, enhances the ...
Donna E Davies, Cornelius Victoria, Grégory Seumois, Lau, LC, Karl J Staples, Cornelius, Victoria, Dorinsky, P, Victoria Cornelius, Davies Donna E., Dinesh Bagmane (457229), Staples, Karl J., Uddin, Mohib, Ratko Djukanović, Pandurangan Vijayanand, Victoria Cornelius (457230), Lau, Laurie C., Mohib Uddin (457226), Karl J. Staples (457228), Bagmane, Dinesh, Ratko Djukanović (457232), Paul Dorinsky, Pandurangan Vijayanand (277869), Djukanović Ratko, Lau, Laurie C, Grégory Seumois (5656213), Lau Laurie C., Staples, KJ, Vijayanand, P, Vijayanand, Pandurangan, Laurie C. Lau (457227), Seumois, G, Uddin, M, Staples, Karl J, Davies, Donna E, Staples Karl J., Davies, DE, Donna E. Davies (137702), Seumois Grégory, Djukanović, R, Dinesh Bagmane, Djukanović, Ratko, Cornelius, V, Davies, Donna E., Laurie C Lau, Dorinsky Paul, Paul Dorinsky (457231), Dorinsky, Paul, Seumois, Grégory, Bagmane Dinesh, Uddin Mohib, Bagmane, D, Mohib Uddin, Vijayanand Pandurangan   +52 more
core   +2 more sources

Some Genetic and Environmental Effects on Equine Asthma in Polish Konik Horses

Animals, 2021
Current knowledge of the genetic and environmental backgrounds of equine asthma seems to be insufficient, especially for primitive horse breeds. The main objectives of this study were to estimate the effects of sex, birth period, stud, parentage line and
Alicja Borowska, Daria Wolska, Artur Niedzwiedz, Hieronim Borowicz, Zbigniew Jaworski, Marta Siemieniuch, Tomasz Szwaczkowski   +6 more
doaj   +1 more source

Long term (5 Year) safety of bronchial thermoplasty: Asthma Intervention Research (AIR) trial [PDF]

, 2011
<b>Background:</b> Bronchial thermoplasty (BT) is a bronchoscopic procedure that improves asthma control by reducing excess airway smooth muscle.
Rubin AS, Rubin Adalberto S, Rubin, A.S., Paul A Corris, D. McCormack (7660568), Adalberto S Rubin, Siersted, HC, Gerard Cox, G. Cox (7598651), Shargill, N.S., Narinder S Shargill, Niven, Robert M, Ronald Olivenstein, Laviolette, M., Robert M Niven, Siersted, H.C., Corris, PA, Rubin, Adalberto S., Corris Paul A, Olivenstein R, Olivenstein Ronald, Olivenstein, R, Shargill, NS, McCormick, D., Rubin, AS, Neil C Thomson, Shargill Narinder S, null null, Laviolette M, Laviolette, M, Rubin, Adalberto S, Olivenstein, R., the AIR Trial Study Group (7660574), AIR Trial Study Group, N.C. Thomson (7660550), Pavord, I.D., Shargill NS, Corris, Paul A., Pavord Ian D, Pavord, Ian D., Niven, RM, Shargill, Narinder S., Michel Laviolette, Thomson, Neil C., David McCormack, N.S. Shargill (7660571), R.M. Niven (7660556), Corris, Paul A, P.A. Corris (7660559), Corris PA, Pavord ID, Corris, P.A., Laviolette Michel, Cox, G, Niven RM, Cox, Gerard, Niven, Robert M., H.C. Siersted (7660562), McCormack David, Pavord, ID, Siersted Hans, Ian D Pavord, McCormack, D, McCormack D, Thomson, N.C., Siersted, Hans Christian, Ian D. Pavord (7582361), Siersted, Hans C., A.S. Rubin (7660553), McCormack, David, Olivenstein, Ronald, Thomson Neil C, R. Olivenstein (7660565), Thomson, NC, Laviolette, Michel, Thomson, Neil C, Niven, R.M., Hans Christian Siersted, Thomson NC, Niven Robert M, Shargill, Narinder S, Cox Gerard, Cox G, Pavord, Ian D, M. Laviolette (3501599), Cox, G., Siersted HC   +86 more
core   +2 more sources

Severe asthma is associated with a remodeling of the pulmonary arteries in horses.

PLoS ONE, 2020
Pulmonary hypertension and cor pulmonale are complications of severe equine asthma, as a consequence of pulmonary hypoxic vasoconstriction. However, as pulmonary hypertension is only partially reversible by oxygen administration, other etiological ...
Serena Ceriotti, Michela Bullone, Mathilde Leclere, Francesco Ferrucci, Jean-Pierre Lavoie   +4 more
doaj   +1 more source