Results 31 to 40 of about 124,917 (127)
Bronchial brush cytology, endobronchial biopsy, and SALSA immunohistochemistry in severe equine asthma. [PDF]
Vet Pathol, 2022 Horses with severe equine asthma (SEA), also known as heaves and recurrent airway obstruction, have persistent neutrophilic inflammation of the lower airways. Cytologic evaluation of bronchoalveolar lavage (BAL) fluid is commonly used to confirm the clinical diagnosis of SEA.
Lee GKC +6 more
europepmc +4 more sources
Efficacy of tamoxifen for the treatment of severe equine asthma. [PDF]
J Vet Intern Med, 2018 Abstract Background Tamoxifen, a selective estrogen receptor modulator, decreased airway neutrophilia and improved clinical signs in an experimental model of equine asthma, and induced neutrophilic apoptosis in vitro.
Mainguy-Seers S, Picotte K, Lavoie JP.
europepmc +4 more sources
Flow cytometric analysis of equine bronchoalveolar lavage fluid cells in horses with and without severe equine asthma. [PDF]
Vet Pathol, 2022 Severe equine asthma (SEA) is a common, debilitating lower airway inflammatory disorder of older horses. Alveolar macrophages (AMs) survey inhaled particulates from barn sources causing them to switch from an anti-inflammatory to a proinflammatory phenotype, resulting in neutrophil recruitment to the lung.
Kang H +6 more
europepmc +4 more sources
Steamed hay and alfalfa pellets for the management of severe equine asthma. [PDF]
Equine Vet JAbstract Background Steaming hay significantly reduces respirable particles and provides a palatable alternative to dry hay for horses with asthma, but there are few prospective studies demonstrating the clinical efficacy of steamed hay.
Symoens A +9 more
europepmc +3 more sources
Efficacy of inhaled budesonide for the treatment of severe equine asthma. [PDF]
Equine Vet J, 2019 Summary Background Corticosteroids are the most potent drugs for the control of severe equine asthma, but adverse effects limit their chronic systemic administration. Inhaled medications allow for drug delivery directly into the airways, reducing the harmful effects of these drugs.
Lavoie JP +7 more
europepmc +4 more sources
Frontiers in Immunology, 2022 Asthma encompasses a spectrum of heterogenous immune-mediated respiratory disorders sharing a similar clinical pattern characterized by cough, wheeze and exercise intolerance.
Pierre Janssen +8 more
doaj +1 more source
Within-Breath Oscillatory Mechanics in Horses Affected by Severe Equine Asthma in Exacerbation and in Remission of the Disease. [PDF]
Animals (Basel), 2021 Oscillometry is a technique that measures the resistance (R) and the reactance (X) of the respiratory system. In humans, analysis of inspiratory and expiratory R and X allows to identify the presence of tidal expiratory flow limitation (EFLt). The aim of this study was to describe inspiratory and expiratory R and X measured by impulse oscillometry ...
Stucchi L +4 more
europepmc +6 more sources
Gene Expression Profiles of the Immuno-Transcriptome in Equine Asthma
Animals, 2022 Background: Mild equine asthma (MEA) and severe equine asthma (SEA) are two of the most frequent equine airway inflammatory diseases, but knowledge about their pathogenesis is limited. The goal of this study was to investigate gene expression differences
Elisa Padoan +5 more
doaj +1 more source
Is inhaled immunotherapy more effective than environmental management when treating equine asthma?
Veterinary Evidence, 2021 PICO question In horses with severe equine asthma syndrome, is inhaled immunotherapy compared to environmental reduction of allergen exposure more effective in disease modification?
Amy Leather, Sarah Smith
doaj +1 more source
Frontiers in Veterinary Science, 2023 Equine asthma is a naturally occurring lung disease characterized by chronic, partially reversible airway obstruction, pulmonary remodeling, and lower airway inflammation.
Jane S. Woodrow +8 more
doaj +1 more source