Steamed hay for the prevention of severe equine asthma exacerbations. [PDF]
Equine Vet JAbstract Background Steaming hay reduces respirable particles and is commonly used to feed horses with asthma. However, it showed inconsistent benefits in clinical studies. Objectives (1) To assess the effects of steamed hay on lung function and airway inflammation in horses with severe equine asthma (SEA) in remission; (2) To compare these effects ...
Raïsky C +8 more
europepmc +4 more sources
Airway Hyperresponsiveness, but Not Bronchoalveolar Inflammatory Cytokines Profiles, Is Modified at the Subclinical Onset of Severe Equine Asthma [PDF]
Animals, 2023 Airway hyperresponsiveness (AHR) and inflammation are both observed in human and equine asthma. The aim of this study was to assess the timeline and relationship of both features at the subclinical onset of severe equine asthma (SEA).
Thibault Frippiat +2 more
doaj +4 more sources
Bronchoalveolar Lavage Cytology in Severe Equine Asthma: Cytocentrifugated versus Sediment Smear Preparations [PDF]
Veterinary Sciences, 2023 Equine asthma is a common respiratory disease that may affect horses of any age. The diagnosis of severe equine asthma (SEA) (historically referred as recurrent airway obstruction or RAO) is based mainly on the history of the animal and clinical signs ...
Maria Morini +7 more
doaj +4 more sources
Immunohistochemical Expression of Neurokinin-A and Interleukin-8 in the Bronchial Epithelium of Horses with Severe Equine Asthma Syndrome during Asymptomatic, Exacerbation, and Remission Phase [PDF]
Animals, 2021 Severe equine asthma (EA) syndrome is a chronic obstructive disease characterized by exaggerated contraction, inflammation, and structural alteration of the airways in adult horses, when exposed to airborne molds and particulate material. However, little
Maria Morini +6 more
doaj +4 more sources
Impaired response of the bronchial epithelium to inflammation characterizes severe equine asthma [PDF]
BMC Genomics, 2017 Background Severe equine asthma is a naturally occurring lung inflammatory disease of mature animals characterized by neutrophilic inflammation, bronchoconstriction, mucus hypersecretion and airway remodeling. Exacerbations are triggered by inhalation of
Laurence Tessier +6 more
doaj +7 more sources
Sequence variant analysis of RNA sequences in severe equine asthma [PDF]
PeerJ, 2018 Background Severe equine asthma is a chronic inflammatory disease of the lung in horses similar to low-Th2 late-onset asthma in humans. This study aimed to determine the utility of RNA-Seq to call gene sequence variants, and to identify sequence variants
Laurence Tessier +2 more
doaj +6 more sources
eQTL discovery and their association with severe equine asthma in European Warmblood horses [PDF]
BMC Genomics, 2018 Background Severe equine asthma, also known as recurrent airway obstruction (RAO), is a debilitating, performance limiting, obstructive respiratory condition in horses that is phenotypically similar to human asthma.
Victor C. Mason +4 more
doaj +6 more sources
Fluticasone/salmeterol reduces remodelling and neutrophilic inflammation in severe equine asthma [PDF]
Scientific Reports, 2017 Asthmatic airways are inflamed and undergo remodelling. Inhaled corticosteroids and long-acting β2-agonist combinations are more effective than inhaled corticosteroid monotherapy in controlling disease exacerbations, but their effect on airway ...
Michela Bullone +4 more
doaj +5 more sources
Multi-Kingdom Fecal Microbiota Alterations in Horses with Severe Equine Asthma [PDF]
MicroorganismsSevere equine asthma (SEA) is a chronic inflammation of airways affecting ~14–20% of adult horses in the Northern Hemisphere. SEA is characterized by a mixed phenotype of T helper cell responses with marked neutrophilia in the bronchoalveolar lavage ...
Rafaela Santos +9 more
doaj +3 more sources
Heart rate variability in horses with and without severe equine asthma [PDF]
Equine Veterinary JournalAbstract Background Equine asthma in severe form (severe equine asthma [sEA]) shares remarkable similarities with human asthma. Human studies detected changes in the autonomic nervous system function in asthmatic patients based on heart rate variability (HRV) analysis.
Zsófia Nyerges-Bohak +2 more
exaly +4 more sources