Results 51 to 60 of about 1,927,081 (168)

Modulatory role of regulatory T cells in a murine model of severe equine asthma. [PDF]

open access: yesBMC Vet Res, 2017
It is accepted that T regulatory cells (Treg) control different types of immune responses. In connection with this role, we have recently described an important increase in CD4+, CD25high, Foxp3+ lymphocytes in the airway system of horses coursing with an exacerbation of severe equine asthma (EA). To explore the potential role of this population in the
Henríquez C   +6 more
europepmc   +5 more sources

Metalloproteinases and their Inhibitors under the Course of Immunostimulation by CPG-ODN and Specific Antigen Inhalation in Equine Asthma

open access: yesMediators of Inflammation, 2019
Objectives. Inhalation of immunostimulatory bacterial DNA segments (cytosine-phosphate-guanosine-oligodeoxynucleotides, CpG-ODN) normalizes clinical and cytologic parameters in severe equine asthma.
Ann Kristin Barton   +5 more
doaj   +1 more source

Managing the pediatric patient with refractory asthma: a multidisciplinary approach [PDF]

open access: yes, 2017
Children with asthma that is refractory to high levels of prescribed treatment are described as having problematic severe asthma. Those in whom persistent symptoms result from a failure of basic asthma management are described as having “difficult asthma”
Winch, D   +21 more
core   +1 more source

Pulmonary vascular remodeling occurs in severe equine asthma.

open access: yes, 2016
Severe equine asthma (heaves) is a chronic genetic-environmental condition characterized by airway neutrophilic inflammation leading to airway obstruction, lung tissue remodeling and hypoxemia (Bullone, 2015). Hypoxemia triggers pulmonary vasoconstriction, resulting in higher vascular resistance and development of pulmonary hypertension (PH).
S. Ceriotti   +5 more
openaire   +3 more sources

A community study of factors related to poorly controlled asthma among Brazilian urban children. [PDF]

open access: yes, 2012
BACKGROUND: Asthma constitutes a serious public health problem in many regions of the world, including the city of Salvador, State of Bahia-Brazil. The purpose of this study was to analyse the factors associated with poor asthma control.
Cruz, Alvaro A.   +30 more
core   +1 more source

Characteristics of Severe Asthma Patients and Predictors of Asthma Control in the Swiss Severe Asthma Registry [PDF]

open access: yes, 2023
BACKGROUND Asthma is a chronic airway disease, affecting over 300 million people worldwide. 5-10% of patients suffer from severe asthma and account for 50% of asthma-related financial burden. Availability of real-life data about the clinical course of
Jaun, Fabienne   +29 more
core   +2 more sources

Allergic rhinitis and its impact on asthma (ARIA): achievements in 10 years and future needs [PDF]

open access: yes, 2012
Allergic rhinitis (AR) and asthma represent global health problems for all age groups. Asthma and rhinitis frequently coexist in the same subjects.
Kaliner, M.A.   +999 more
core   +1 more source

A Twin Study of Early-Childhood Asthma in Puerto Ricans [PDF]

open access: yes, 2013
Background:The relative contributions of genetics and environment to asthma in Hispanics or to asthma in children younger than 3 years are not well understood.Objective:To examine the relative contributions of genetics and environment to early-childhood ...
Canino Glorisa   +39 more
core   +1 more source

Tracheal wash culture is not associated with bronchial infection, remodelling or inflammation in horses with asthma

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background Antimicrobials are commonly prescribed for the treatment of equine asthma, despite limited evidence supporting their use. Tracheal wash (TW) bacterial culture results are known to influence antimicrobial prescription decisions. Objectives To determine whether a positive TW bacterial culture in horses with asthma is associated with ...
Laurence Leduc   +2 more
wiley   +1 more source

A Portable Fluorometer Detects Significantly Elevated Cell-Free DNA in Tracheal Wash and Bronchoalveolar Lavage Fluid in Horses with Severe Asthma

open access: yesAnimals
Severe equine asthma (sEA) is characterized by increased lower airway neutrophils that contribute to dysregulated inflammation through the release of cytokines, reactive oxygen species and neutrophil extracellular traps (NETs).
Bethanie L. Cooper   +7 more
doaj   +1 more source

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