Results 51 to 60 of about 124,917 (127)

Metalloproteinases and their Inhibitors under the Course of Immunostimulation by CPG-ODN and Specific Antigen Inhalation in Equine Asthma

Mediators of Inflammation, 2019
Objectives. Inhalation of immunostimulatory bacterial DNA segments (cytosine-phosphate-guanosine-oligodeoxynucleotides, CpG-ODN) normalizes clinical and cytologic parameters in severe equine asthma.
Ann Kristin Barton, Tarek Shety, John Klier, Sabine Geis, Ralf Einspanier, Heidrun Gehlen   +5 more
doaj   +1 more source

Tracheal wash culture is not associated with bronchial infection, remodelling or inflammation in horses with asthma

Equine Veterinary Journal, EarlyView.
Abstract Background Antimicrobials are commonly prescribed for the treatment of equine asthma, despite limited evidence supporting their use. Tracheal wash (TW) bacterial culture results are known to influence antimicrobial prescription decisions. Objectives To determine whether a positive TW bacterial culture in horses with asthma is associated with ...
Laurence Leduc, Guillaume St‐Jean, Jean‐Pierre Lavoie   +2 more
wiley   +1 more source

Oscillometric assessment of bronchodilator response in horses with severe asthma during remission

Equine Veterinary Journal, EarlyView.
Abstract Background During clinical remission of severe equine asthma (SEA), affected animals can be challenging to distinguish from healthy horses. In humans, the degree of bronchodilation achieved with a β2‐adrenergic bronchodilator is helpful in differentiating asthmatics from healthy subjects.
Séléna de Wasseige, Sophie Mainguy‐Seers, Jean‐Pierre Lavoie   +2 more
wiley   +1 more source

Bronchial but not Tracheal Smooth Muscle is Hypercontractile in an Equine Model of Severe Asthma [PDF]

Biophysical Journal, 2015
Asthma is an inflammatory disease of the airways characterized by airway hyperresponsiveness, an exaggerated bronchoconstrictive response of airway smooth muscle (ASM) to stimuli. However, whether asthmatic ASM is mechanically different from non-asthmatic ASM is still unclear.
Matusovsky, Oleg S., Kachmar, Linda, Ipgma, Gijs, Zitouni, Nedjma, Bates, Genevieve, Lavoie, Jean-Pierre, Lauzon, Anne-Marie   +6 more
openaire   +1 more source

Equine alveolar macrophages and monocyte-derived macrophages respond differently to an inflammatory stimulus

PLoS ONE, 2023
Alveolar macrophages (AMs) are the predominant innate immune cell in the distal respiratory tract. During inflammatory responses, AMs may be supplemented by blood monocytes, which differentiate into monocyte-derived macrophages (MDMs).
Heng Kang, Gary Kwok Cheong Lee, Dorothee Bienzle, Luis G. Arroyo, William Sears, Brandon N. Lillie, Janet Beeler-Marfisi   +6 more
doaj   +2 more sources

Tapeworm testing: Coprological and antibody‐based approaches across colic types in a German equine hospital population

Equine Veterinary Education, EarlyView.
Summary Background The association between tapeworm infection and equine colic is established, but gaps remain regarding specific colic types. Objectives To assess the relationship between tapeworm test results and equine colic types: The study aimed to determine if ileocaecal disorders (IC) are more frequently associated with Anoplocephala spp ...
K. L. Adamasky, K. Drozdzewska, P. Schmitz, N. Peczak, K. L. Lightbody, J. B. Matthews, M. K. Nielsen, R. Merle, G. von Samson‐Himmelstjerna, H. Gehlen   +9 more
wiley   +1 more source

Response to equine cardiac adverse events during sports

Equine Veterinary Education, EarlyView.
Summary Cardiac adverse events and sudden death are a feared scenario for equine veterinarians, with serious consequences for animal health, riders' safety and the social licence to operate equestrian sports. The response to equine cardiac adverse events (CAEs) during sports is poorly defined.
C. Navas de Solis, J. Keen, A. Decloedt, B. Delvescovo, K. Hopster, K. Mitchell, J. Slack, G. van Loon, G. Van Steenkiste, L. Nath   +9 more
wiley   +1 more source

Redox Biomarker Variations With Severity of Asthma in Horses Across Different Sample Types

Journal of Veterinary Internal Medicine
Background The contribution of redox imbalance to equine asthma (EA) pathogenesis remains unclear. Objectives (1) validate and measure a panel of redox biomarkers in the tracheal wash (TW) and bronchoalveolar lavage (BAL) samples from horses with ...
Sanni Hansen, Nina D. Otten, Jose Joaquin Ceron, Luis Guillermo González‐Arostegui, Camila Peres‐Rubio   +4 more
doaj   +1 more source

Field‐applicable low‐intensity exercise induces bronchodilation in horses with severe asthma

Equine Veterinary Journal, EarlyView.
Abstract Background Airway dysfunction in severe equine asthma (SEA) often results in early retirement or euthanasia of affected horses. Exercise‐induced bronchodilation occurs in horses with SEA after intense treadmill exercise, but the effects of a lighter, field‐applicable, training regimen remain largely unexplored.
Sophie Mainguy‐Seers, Sarah‐Maude Grondin, Jean‐Pierre Lavoie   +2 more
wiley   +1 more source

Pulmonary Remodeling in Equine Asthma: What Do We Know about Mediators of Inflammation in the Horse?

Mediators of Inflammation, 2016
Equine inflammatory airway disease (IAD) and recurrent airway obstruction (RAO) represent a spectrum of chronic inflammatory disease of the airways in horses resembling human asthma in many aspects. Therefore, both are now described as severity grades of
Ann Kristin Barton, Heidrun Gehlen
doaj   +1 more source