Results 41 to 50 of about 319,696 (309)

Mapping the impacts of climate change on vector-borne diseases : application to Orbiviruses [PDF]

open access: yes, 2010
Climate impacts vector-borne disease transmission through a complex interplay of influences on all the actors involved: the vector, the host and the pathogen.
Baylis, Matthew   +4 more
core  

In vitro susceptibility of 120 strains of Neisseria gonorrhoeae isolated in Kyrghyzstan. [PDF]

open access: yes, 2002
BACKGROUND: The World Health Organization has established a worldwide program for gonococcal antimicrobial surveillance, but so far no data on gonococcal susceptibility in Central Asia are available.
Boireaux, C   +4 more
core   +2 more sources

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

Effect of a Histone Demethylase Inhibitor on Equine Herpesvirus-1 Activity In Vitro

open access: yesFrontiers in Veterinary Science, 2018
Equine herpesvirus type 1 (EHV-1) is a ubiquitous and highly contagious pathogen that causes a range of disease severities with outbreaks of notable economic impact.
Rebecca L. Tallmadge   +4 more
doaj   +1 more source

Retinal glycoprotein enrichment by concanavalin a enabled identification of novel membrane autoantigen synaptotagmin-1 in equine recurrent uveitis. [PDF]

open access: yes, 2012
Complete knowledge of autoantigen spectra is crucial for understanding pathomechanisms of autoimmune diseases like equine recurrent uveitis (ERU), a spontaneous model for human autoimmune uveitis. While several ERU autoantigens were identified previously,
A Lux   +68 more
core   +2 more sources

[Crazy horse disease].

open access: yesRevista chilena de infectologia : organo oficial de la Sociedad Chilena de Infectologia, 2019
With the apparition of the crazy cows disease at the end of twentieth century, great was the temptation for denominate "crazy horses disease" an ancient enzootic encephalo-myelitis, known from the 17th century and now named "Borna disease" in 1970, because severe outbreaks affecting horses in this city of Germany since 1885.
openaire   +2 more sources

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

open access: yesAging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey   +12 more
wiley   +1 more source

Prevalence of respiratory pathogens in nasal swabs from horses with acute respiratory disease in Belgium [PDF]

open access: yes, 2016
Contagious respiratory infections are an important cause of respiratory disease in horses, resulting in impaired pulmonary function, poor performance and sometimes severe illness.
Amory, H   +7 more
core  

Pneumonia Caused by Klebsiella spp. in 46 Horses. [PDF]

open access: yes, 2015
BackgroundKlebsiella spp. are implicated as a common cause of bacterial pneumonia in horses, but few reports describe clinical presentation and disease progression.Hypothesis/objectivesTo describe the signalment, clinicopathologic data, radiographic and ...
Aleman, M   +7 more
core   +1 more source

Microfluidic Platform for Multiparametric Profiling of Fibrin Permeability, Fibrinolysis, and Cell Invasion

open access: yesAdvanced Functional Materials, EarlyView.
This paper introduces a single‐channel H‐junction microfluidic assay that profiles fibrin's evolving function in repair and thrombosis by measuring, in one ∼3 µL gel, permeability, fibrinolysis kinetics, fibroblast invasion, and clot extension in real time.
Halston Deal   +9 more
wiley   +1 more source

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