ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan +9 more
wiley +1 more source
Substitution of additives in horseradish sauce: technological strategies and efficacy
An additive-free horseradish sauce was produced by replacing citric acid and sulfites, commonly used as acidifying, and antimicrobial/anti-browning agents, respectively.
Flavia Bianchi +5 more
doaj +1 more source
Objective The goal was to assess the diagnostic performance of three novel autoantibodies (NA) for Sjögren disease (SjD) by comparing NA prevalence in patients with SjD, other autoimmune rheumatic diseases (ARDs), nonspecific chronic sialadenitis (CS), and controls.
Chadwick R. Johr +5 more
wiley +1 more source
Peroxidase-mediated cross-linking of bovine a-lactalbumin
The research presented in this thesis aimed at controlling the horseradish peroxidase-catalyzed cross-linking of bovine α lactalbumin and the implications of this cross-linking for the foam stabilizing properties. Attention is also given to microreactors
Heijnis, W.H.
core
Impact of an Ionic Liquid Solution on Horseradish Peroxidase Activity
Horseradish peroxidase (HRP) is an important enzyme for industrial purposes due to its ability to oxidize pollutants from wastewater. A previous report indicated that peroxidases can have up to a 20% increase in the initial enzymatic activity in an ...
G. Andrés, Cisneros +2 more
core +1 more source
Comparison of chromogens for the determination of horseradish peroxidase as a marker in enzyme immunoassay [PDF]
4-aminoantipyrine were compared as chromogens for the determination of horseradish peroxidase. Highest sensitivity in the determination of horseradish peroxidase-IgG conjugates in dissolved form was obtained with o-phenylenedia-mine.
Bärbel Porstmann +5 more
core +1 more source
LC-MSMS based screening of emerging pollutant degradation by different peroxidases
Background The presence of a wide range of bioactive organic pollutants in wastewater and municipal water sources is raising concerns about their potential effects on humans.
Khadega A. Almaqdi +4 more
doaj +1 more source
Electrochemical Behaviors of Horseradish Peroxidase on MoS2 Nanosheets Modified Electrode
In this paper molybdenum disulfide (MoS2) nanosheets and horseradish peroxidase (HRP) modified electrode was prepared with ionic liquid 1-hexylpyridinium hexafluorophosphate based carbon ionic liquid electrode (CILE). UV-Vis and FT-IR spectra showed that
Wen Zheng +5 more
doaj +1 more source
β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio +11 more
wiley +1 more source
Localization of brain stem motoneurons innervating the laryngeal muscles in the rufous horseshoe bat,rhinolophus rouxi [PDF]
The motoneurons innervating the laryngeal muscles were localized in the rufous horseshoe bat,Rhinolophus rouxi, using the HRP method. HRP was applied to the cricothyroid muscle and to the cut end of the recurrent laryngeal nerve. Labeled motoneurons were
Rübsamen, R. +2 more
core +1 more source

